Time-of-flight angiography: a viable alternative to contrast-enhanced MR angiography and fat-suppressed T1w images for the diagnosis of cervical artery dissection?
Saved in:
| Title: | Time-of-flight angiography: a viable alternative to contrast-enhanced MR angiography and fat-suppressed T1w images for the diagnosis of cervical artery dissection? |
|---|---|
| Authors: | Coppenrath, E.1, Lummel, N.2, Linn, J.2, Lenz, O.1, Habs, M.3, Nikolaou, K.1, Reiser, M.1, Dichgans, M.4, Pfefferkorn, T.3, Saam, T.1 tobias.saam@med.lmu.de |
| Source: | European Radiology. Oct2013, Vol. 23 Issue 10, p2784-2792. 9p. 4 Black and White Photographs, 3 Charts. |
| Subjects: | Time-of-flight measurements, Magnetic resonance angiography, Arterial diseases, Magnetic resonance imaging, Vertebral artery dissections, Cerebrovascular disease, Diagnosis |
| Abstract: | Objectives: To compare the use of an unenhanced high-resolution time-of-flight MR angiography sequence (Hr-TOF MRA) with fat-suppressed axial/coronal T1-weighted images and contrast-enhanced angiography (standard MRI) for the diagnosis of cervical artery dissection (cDISS). Methods: Twenty consecutive patients (9 women, 11 men, aged 24-66 years) with proven cDISS on standard MRI underwent Hr-TOF MRA at 3.0 T using dedicated surface coils. Sensitivity (SE), specificity (SP), positive and negative predictive values (PPV, NPV), Cohen's kappa (к) and accuracy of Hr-TOF MRA were calculated using the standard protocol as the gold standard. Image quality and diagnostic confidence were assessed on a four-point scale. Results: Image quality was rated better for standard MRI ( P = 0.02), whereas diagnostic confidence did not differ significantly ( P = 0.27). There was good agreement between Hr-TOF images and the standard protocol for the presence/absence of cDISS, with к = 0.95 for reader 1 and к = 0.89 for reader 2 ( P < 0.001). This resulted in SE, SP, PPV, NPV and accuracy of 97 %, 98 %, 97 %, 98 % and 97 % for reader 1 and 93 %, 96 %, 93 %, 96 % and 95 % for reader 2. Conclusions: Hr-TOF MRA can be used to diagnose cDISS with excellent agreement compared with the standard protocol. This might be useful in patients with renal insufficiency or if contrast-enhanced MR angiography is of insufficient image quality. Key Points: • New magnetic resonance angiography sequences are increasingly used for vertebral artery assessment. • A high-resolution time-of-flight sequence allows the diagnosis of cervical artery dissection. • This technique allows the diagnosis without intravenous contrast medium. • It could help in renal insufficiency or when contrast-enhanced MRA fails. [ABSTRACT FROM AUTHOR] |
| Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 90169460 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Time-of-flight angiography: a viable alternative to contrast-enhanced MR angiography and fat-suppressed T1w images for the diagnosis of cervical artery dissection? – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Coppenrath%2C+E%2E%22">Coppenrath, E.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Lummel%2C+N%2E%22">Lummel, N.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Linn%2C+J%2E%22">Linn, J.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Lenz%2C+O%2E%22">Lenz, O.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Habs%2C+M%2E%22">Habs, M.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Nikolaou%2C+K%2E%22">Nikolaou, K.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Reiser%2C+M%2E%22">Reiser, M.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Dichgans%2C+M%2E%22">Dichgans, M.</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Pfefferkorn%2C+T%2E%22">Pfefferkorn, T.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Saam%2C+T%2E%22">Saam, T.</searchLink><relatesTo>1</relatesTo><i> tobias.saam@med.lmu.de</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Radiology%22">European Radiology</searchLink>. Oct2013, Vol. 23 Issue 10, p2784-2792. 9p. 4 Black and White Photographs, 3 Charts. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Time-of-flight+measurements%22">Time-of-flight measurements</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+angiography%22">Magnetic resonance angiography</searchLink><br /><searchLink fieldCode="DE" term="%22Arterial+diseases%22">Arterial diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Vertebral+artery+dissections%22">Vertebral artery dissections</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebrovascular+disease%22">Cerebrovascular disease</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis%22">Diagnosis</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objectives: To compare the use of an unenhanced high-resolution time-of-flight MR angiography sequence (Hr-TOF MRA) with fat-suppressed axial/coronal T1-weighted images and contrast-enhanced angiography (standard MRI) for the diagnosis of cervical artery dissection (cDISS). Methods: Twenty consecutive patients (9 women, 11 men, aged 24-66 years) with proven cDISS on standard MRI underwent Hr-TOF MRA at 3.0 T using dedicated surface coils. Sensitivity (SE), specificity (SP), positive and negative predictive values (PPV, NPV), Cohen's kappa (к) and accuracy of Hr-TOF MRA were calculated using the standard protocol as the gold standard. Image quality and diagnostic confidence were assessed on a four-point scale. Results: Image quality was rated better for standard MRI ( P = 0.02), whereas diagnostic confidence did not differ significantly ( P = 0.27). There was good agreement between Hr-TOF images and the standard protocol for the presence/absence of cDISS, with к = 0.95 for reader 1 and к = 0.89 for reader 2 ( P < 0.001). This resulted in SE, SP, PPV, NPV and accuracy of 97 %, 98 %, 97 %, 98 % and 97 % for reader 1 and 93 %, 96 %, 93 %, 96 % and 95 % for reader 2. Conclusions: Hr-TOF MRA can be used to diagnose cDISS with excellent agreement compared with the standard protocol. This might be useful in patients with renal insufficiency or if contrast-enhanced MR angiography is of insufficient image quality. Key Points: • New magnetic resonance angiography sequences are increasingly used for vertebral artery assessment. • A high-resolution time-of-flight sequence allows the diagnosis of cervical artery dissection. • This technique allows the diagnosis without intravenous contrast medium. • It could help in renal insufficiency or when contrast-enhanced MRA fails. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=90169460 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00330-013-2891-1 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 2784 Subjects: – SubjectFull: Time-of-flight measurements Type: general – SubjectFull: Magnetic resonance angiography Type: general – SubjectFull: Arterial diseases Type: general – SubjectFull: Magnetic resonance imaging Type: general – SubjectFull: Vertebral artery dissections Type: general – SubjectFull: Cerebrovascular disease Type: general – SubjectFull: Diagnosis Type: general Titles: – TitleFull: Time-of-flight angiography: a viable alternative to contrast-enhanced MR angiography and fat-suppressed T1w images for the diagnosis of cervical artery dissection? Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Coppenrath, E. – PersonEntity: Name: NameFull: Lummel, N. – PersonEntity: Name: NameFull: Linn, J. – PersonEntity: Name: NameFull: Lenz, O. – PersonEntity: Name: NameFull: Habs, M. – PersonEntity: Name: NameFull: Nikolaou, K. – PersonEntity: Name: NameFull: Reiser, M. – PersonEntity: Name: NameFull: Dichgans, M. – PersonEntity: Name: NameFull: Pfefferkorn, T. – PersonEntity: Name: NameFull: Saam, T. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2013 Type: published Y: 2013 Identifiers: – Type: issn-print Value: 09387994 Numbering: – Type: volume Value: 23 – Type: issue Value: 10 Titles: – TitleFull: European Radiology Type: main |
| ResultId | 1 |
