Feasibility study into use of elemental impurities of sulfamide for use in characterizing different vendors by inductively coupled plasma/mass spectrometry.
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| Title: | Feasibility study into use of elemental impurities of sulfamide for use in characterizing different vendors by inductively coupled plasma/mass spectrometry. |
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| Authors: | Hondrogiannis, Ellen1 EHondrogiannis@towson.edu, Schmidt, Andrew1, Iannaconi, Frank1, Ehrlinger, Erin1 |
| Source: | Forensic Science International. 2013, Vol. 232 Issue 1-3, p56-59. 4p. |
| Subjects: | Sulfamide, Impurity-dislocation interactions, Mass spectrometry, Neurotoxic agents, Feasibility studies |
| Abstract: | Inductively coupled plasma-mass spectrometery (ICP-MS) was used to quantitate elemental impurities in sulfamide from seven common vendors, Acros, Aldrich, Alfa-Aesar, Fluka (Lot #1 and Lot #2), Maybridge, Pfaltz and Bauer, and Spectrum (Lot #1 and Lot #2) with the goal of using these impurities to differentiate the sulfamide samples and link the sulfamide back to its vendor. This attribution of the sulfamide back to its vendor is forensically relevant since sulfamide is a precursor to the deadly neurotoxin, tetramethylenedisulfotetramine (TETS). Solution ICP mass spectra identified statistically different concentrations of Cu, Fe, Ni, and Zn among some of the vendors and even in the same lots of the same vendor. These elemental concentrations were entered into discriminant functions which resulted in successful discrimination among the vendors. The two lots of Spectrum were also differentiated while one lot of Fluka was misclassified as the other Fluka lot. These preliminary results indicate the feasibility of using inorganic impurities to cluster vendors with the potential for association or disassociation of an unknown back to a vendor. [ABSTRACT FROM AUTHOR] |
| Copyright of Forensic Science International is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 90327046 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Feasibility study into use of elemental impurities of sulfamide for use in characterizing different vendors by inductively coupled plasma/mass spectrometry. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Hondrogiannis%2C+Ellen%22">Hondrogiannis, Ellen</searchLink><relatesTo>1</relatesTo><i> EHondrogiannis@towson.edu</i><br /><searchLink fieldCode="AR" term="%22Schmidt%2C+Andrew%22">Schmidt, Andrew</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Iannaconi%2C+Frank%22">Iannaconi, Frank</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ehrlinger%2C+Erin%22">Ehrlinger, Erin</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Forensic+Science+International%22">Forensic Science International</searchLink>. 2013, Vol. 232 Issue 1-3, p56-59. 4p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Sulfamide%22">Sulfamide</searchLink><br /><searchLink fieldCode="DE" term="%22Impurity-dislocation+interactions%22">Impurity-dislocation interactions</searchLink><br /><searchLink fieldCode="DE" term="%22Mass+spectrometry%22">Mass spectrometry</searchLink><br /><searchLink fieldCode="DE" term="%22Neurotoxic+agents%22">Neurotoxic agents</searchLink><br /><searchLink fieldCode="DE" term="%22Feasibility+studies%22">Feasibility studies</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Inductively coupled plasma-mass spectrometery (ICP-MS) was used to quantitate elemental impurities in sulfamide from seven common vendors, Acros, Aldrich, Alfa-Aesar, Fluka (Lot #1 and Lot #2), Maybridge, Pfaltz and Bauer, and Spectrum (Lot #1 and Lot #2) with the goal of using these impurities to differentiate the sulfamide samples and link the sulfamide back to its vendor. This attribution of the sulfamide back to its vendor is forensically relevant since sulfamide is a precursor to the deadly neurotoxin, tetramethylenedisulfotetramine (TETS). Solution ICP mass spectra identified statistically different concentrations of Cu, Fe, Ni, and Zn among some of the vendors and even in the same lots of the same vendor. These elemental concentrations were entered into discriminant functions which resulted in successful discrimination among the vendors. The two lots of Spectrum were also differentiated while one lot of Fluka was misclassified as the other Fluka lot. These preliminary results indicate the feasibility of using inorganic impurities to cluster vendors with the potential for association or disassociation of an unknown back to a vendor. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Forensic Science International is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.forsciint.2013.07.001 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 4 StartPage: 56 Subjects: – SubjectFull: Sulfamide Type: general – SubjectFull: Impurity-dislocation interactions Type: general – SubjectFull: Mass spectrometry Type: general – SubjectFull: Neurotoxic agents Type: general – SubjectFull: Feasibility studies Type: general Titles: – TitleFull: Feasibility study into use of elemental impurities of sulfamide for use in characterizing different vendors by inductively coupled plasma/mass spectrometry. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hondrogiannis, Ellen – PersonEntity: Name: NameFull: Schmidt, Andrew – PersonEntity: Name: NameFull: Iannaconi, Frank – PersonEntity: Name: NameFull: Ehrlinger, Erin IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2013 Type: published Y: 2013 Identifiers: – Type: issn-print Value: 03790738 Numbering: – Type: volume Value: 232 – Type: issue Value: 1-3 Titles: – TitleFull: Forensic Science International Type: main |
| ResultId | 1 |
