Bibliographic Details
| Title: |
Chaperonin-mediated protein folding at the surface of groEL through a `molten globule'-like... |
| Authors: |
Martin, J., Langer, T. |
| Source: |
Nature. 7/4/1991, Vol. 352 Issue 6330, p36. 7p. 6 Black and White Photographs, 1 Diagram, 1 Chart, 14 Graphs. |
| Subjects: |
Protein research |
| Abstract: |
Presents the reproduction of the chaperonin-dependent folding of two monomeric enzymes, dihydrofolate reductase (DHFR) and rhodanese, using the groEL and groES proteins of `Escherichia coli.' GroEL stabilizing a `molten globule'-like state; DHFRfolding through a more compact intermediate; GroES and folding at the groEL surface; ATP requirement at folding. |
| Database: |
Engineering Source |
