A review of environmental toxicant analysis by using multidimensional gas chromatography and comprehensive GC
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| Title: | A review of environmental toxicant analysis by using multidimensional gas chromatography and comprehensive GC |
|---|---|
| Authors: | Marriott, Philip J.1 philip.marriott@rmit.edu.au, Haglund, Peter2, Ong, Ruby C.Y.1 |
| Source: | Clinica Chimica Acta. Feb2003, Vol. 328 Issue 1/2, p1. 19p. |
| Subjects: | Pollutants, Gas chromatography |
| Abstract: | The purpose of this review is to highlight the developments in coupled-column gas chromatography methods for qualitative analysis of selected environmental toxicants such as dioxin, polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), etc. In particular, the new technique of GC×GC will be introduced, and its role, and the promise it offers to this field is discussed. The benefits of enhanced separation to quantitative analysis will be considered.In order to perform an accurate risk assessment, both the dose and biological effects of environmental toxicants have to be determined with a high degree of certainty. This is most often achieved by using chromatographic methods. Given the complexity of most environmental sample extracts, single-column gas chromatography is unable to fully resolve all the components of interest frequently leading to a positive bias in the reported concentrations. Advanced separation tools, such as multidimensional gas chromatography (MDGC), were investigated quite early and demonstrated improvements in separation. However, limitations in the number of target analytes that could be analyzed in a single run as well as insufficient robustness lead to a continued interest in alternative solutions. The parallel development of mass spectrometric identification and quantification strategies proved useful in many cases, although it frequently failed to provide positive identification of chromatographically unresolved isomeric compounds. More recently, comprehensive two-dimensional gas chromatography (GC×GC) may offer a solution to that problem, especially because it offers enhanced resolution for complex mixtures containing trace level environmental toxicants. [Copyright &y& Elsevier] |
| Copyright of Clinica Chimica Acta is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 9144982 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/S0009-8981(02)00382-0 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 19 StartPage: 1 Subjects: – SubjectFull: Pollutants Type: general – SubjectFull: Gas chromatography Type: general Titles: – TitleFull: A review of environmental toxicant analysis by using multidimensional gas chromatography and comprehensive GC Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Marriott, Philip J. – PersonEntity: Name: NameFull: Haglund, Peter – PersonEntity: Name: NameFull: Ong, Ruby C.Y. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2003 Type: published Y: 2003 Identifiers: – Type: issn-print Value: 00098981 Numbering: – Type: volume Value: 328 – Type: issue Value: 1/2 Titles: – TitleFull: Clinica Chimica Acta Type: main |
| ResultId | 1 |
