Reversed phase free ion selective radiotracer extraction (RP-FISRE): A new tool to assess the dynamic stabilities of metal (-organic) complexes, for complex half-lives spanning six orders of magnitude.
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| Title: | Reversed phase free ion selective radiotracer extraction (RP-FISRE): A new tool to assess the dynamic stabilities of metal (-organic) complexes, for complex half-lives spanning six orders of magnitude. |
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| Authors: | van der Meer, Astrid1 A.J.G.M.vandermeer@tudelft.nl, Breeman, Wouter A.P.2, Wolterbeek, Bert1 |
| Source: | Applied Radiation & Isotopes. Dec2013, Vol. 82, p28-35. 8p. |
| Subjects: | Radioactive tracers, Dynamic stability, Metal complexes, Elution (Chromatography), Performance evaluation, Solid phase extraction |
| Abstract: | Abstract: This paper introduces reversed phase free ion selective radiotracer extraction (RP-FISRE) as a new tool to assess the stability of metal complexes, as illustrated by the assessment of the stability of [177Lu]Lu-DOTA-octreotate. To this end, the TUDelft-developed FISRE, where the released metal is column-retained and the complex eluted, was changed into RP-FISRE, where the complex is column-retained and the released metal is eluted. This change in the approach allows for studies to be performed with high stability complexes. This paper presents RP-FISRE, the strength of the radiotracer approach, and the first-ever k d data on the release of 177Lu from [177Lu]Lu-DOTA-octreotate. [Copyright &y& Elsevier] |
| Copyright of Applied Radiation & Isotopes is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 91970843 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Reversed phase free ion selective radiotracer extraction (RP-FISRE): A new tool to assess the dynamic stabilities of metal (-organic) complexes, for complex half-lives spanning six orders of magnitude. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22van+der+Meer%2C+Astrid%22">van der Meer, Astrid</searchLink><relatesTo>1</relatesTo><i> A.J.G.M.vandermeer@tudelft.nl</i><br /><searchLink fieldCode="AR" term="%22Breeman%2C+Wouter+A%2EP%2E%22">Breeman, Wouter A.P.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Wolterbeek%2C+Bert%22">Wolterbeek, Bert</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Applied+Radiation+%26+Isotopes%22">Applied Radiation & Isotopes</searchLink>. Dec2013, Vol. 82, p28-35. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Radioactive+tracers%22">Radioactive tracers</searchLink><br /><searchLink fieldCode="DE" term="%22Dynamic+stability%22">Dynamic stability</searchLink><br /><searchLink fieldCode="DE" term="%22Metal+complexes%22">Metal complexes</searchLink><br /><searchLink fieldCode="DE" term="%22Elution+%28Chromatography%29%22">Elution (Chromatography)</searchLink><br /><searchLink fieldCode="DE" term="%22Performance+evaluation%22">Performance evaluation</searchLink><br /><searchLink fieldCode="DE" term="%22Solid+phase+extraction%22">Solid phase extraction</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract: This paper introduces reversed phase free ion selective radiotracer extraction (RP-FISRE) as a new tool to assess the stability of metal complexes, as illustrated by the assessment of the stability of [177Lu]Lu-DOTA-octreotate. To this end, the TUDelft-developed FISRE, where the released metal is column-retained and the complex eluted, was changed into RP-FISRE, where the complex is column-retained and the released metal is eluted. This change in the approach allows for studies to be performed with high stability complexes. This paper presents RP-FISRE, the strength of the radiotracer approach, and the first-ever k d data on the release of 177Lu from [177Lu]Lu-DOTA-octreotate. [Copyright &y& Elsevier] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Applied Radiation & Isotopes is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.apradiso.2013.06.021 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 28 Subjects: – SubjectFull: Radioactive tracers Type: general – SubjectFull: Dynamic stability Type: general – SubjectFull: Metal complexes Type: general – SubjectFull: Elution (Chromatography) Type: general – SubjectFull: Performance evaluation Type: general – SubjectFull: Solid phase extraction Type: general Titles: – TitleFull: Reversed phase free ion selective radiotracer extraction (RP-FISRE): A new tool to assess the dynamic stabilities of metal (-organic) complexes, for complex half-lives spanning six orders of magnitude. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: van der Meer, Astrid – PersonEntity: Name: NameFull: Breeman, Wouter A.P. – PersonEntity: Name: NameFull: Wolterbeek, Bert IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2013 Type: published Y: 2013 Identifiers: – Type: issn-print Value: 09698043 Numbering: – Type: volume Value: 82 Titles: – TitleFull: Applied Radiation & Isotopes Type: main |
| ResultId | 1 |
