An analytical model to predict interstitial lubrication of cartilage in migrating contact areas.
Saved in:
| Title: | An analytical model to predict interstitial lubrication of cartilage in migrating contact areas. |
|---|---|
| Authors: | Moore, A. C.1, Burris, D. L.1,2 dlburris@udel.edu |
| Source: | Journal of Biomechanics. 2014, Vol. 47 Issue 1, p148-153. 6p. |
| Subjects: | Extracellular fluid, Cartilage, Tribology, Biomimetic chemicals, Biomechanics, Osteoarthritis |
| Abstract: | For nearly a century, articular cartilage has been known for its exceptional tribological properties. For nearly as long, there have been research efforts to elucidate the responsible mechanisms for application toward biomimetic bearing applications. It is now widely accepted that interstitial fluid pressurization is the primary mechanism responsible for the unusual lubrication and load bearing properties of cartilage. Although the biomechanics community has developed elegant mathematical theories describing the coupling of solid and fluid (biphasic) mechanics and its role in interstitial lubrication, quantitative gaps in our understanding of cartilage tribology have inhibited our ability to predict how tribological conditions and material properties impact tissue function. This paper presents an analytical model of the interstitial lubrication of biphasic materials under migrating contact conditions. Although finite element and other numerical models of cartilage mechanics exist, they typically neglect the important role of the collagen network and are limited to a specific set of input conditions, which limits general applicability. The simplified approach taken in this work aims to capture the broader underlying physics as a starting point for further model development. In agreement with existing literature, the model indicates that a large Peclet number, Pe, is necessary for effective interstitial lubrication. It also predicts that the tensile modulus must be large relative to the compressive modulus. This explains why hydrogels and other biphasic materials do not provide significant interstitial pressure under high Pe conditions. The model quantitatively agrees with in-situ measurements of interstitial load support and the results have interesting implications for tissue engineering and osteoarthritis problems. This paper suggests that a low tensile modulus (from chondromalacia or local collagen rupture after impact, for example) may disrupt interstitial pressurization, increase shear stresses, and activate a condition of progressive surface damage as a potential precursor of osteoarthritis. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 93306494 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: An analytical model to predict interstitial lubrication of cartilage in migrating contact areas. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Moore%2C+A%2E+C%2E%22">Moore, A. C.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Burris%2C+D%2E+L%2E%22">Burris, D. L.</searchLink><relatesTo>1,2</relatesTo><i> dlburris@udel.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Biomechanics%22">Journal of Biomechanics</searchLink>. 2014, Vol. 47 Issue 1, p148-153. 6p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Extracellular+fluid%22">Extracellular fluid</searchLink><br /><searchLink fieldCode="DE" term="%22Cartilage%22">Cartilage</searchLink><br /><searchLink fieldCode="DE" term="%22Tribology%22">Tribology</searchLink><br /><searchLink fieldCode="DE" term="%22Biomimetic+chemicals%22">Biomimetic chemicals</searchLink><br /><searchLink fieldCode="DE" term="%22Biomechanics%22">Biomechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Osteoarthritis%22">Osteoarthritis</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: For nearly a century, articular cartilage has been known for its exceptional tribological properties. For nearly as long, there have been research efforts to elucidate the responsible mechanisms for application toward biomimetic bearing applications. It is now widely accepted that interstitial fluid pressurization is the primary mechanism responsible for the unusual lubrication and load bearing properties of cartilage. Although the biomechanics community has developed elegant mathematical theories describing the coupling of solid and fluid (biphasic) mechanics and its role in interstitial lubrication, quantitative gaps in our understanding of cartilage tribology have inhibited our ability to predict how tribological conditions and material properties impact tissue function. This paper presents an analytical model of the interstitial lubrication of biphasic materials under migrating contact conditions. Although finite element and other numerical models of cartilage mechanics exist, they typically neglect the important role of the collagen network and are limited to a specific set of input conditions, which limits general applicability. The simplified approach taken in this work aims to capture the broader underlying physics as a starting point for further model development. In agreement with existing literature, the model indicates that a large Peclet number, Pe, is necessary for effective interstitial lubrication. It also predicts that the tensile modulus must be large relative to the compressive modulus. This explains why hydrogels and other biphasic materials do not provide significant interstitial pressure under high Pe conditions. The model quantitatively agrees with in-situ measurements of interstitial load support and the results have interesting implications for tissue engineering and osteoarthritis problems. This paper suggests that a low tensile modulus (from chondromalacia or local collagen rupture after impact, for example) may disrupt interstitial pressurization, increase shear stresses, and activate a condition of progressive surface damage as a potential precursor of osteoarthritis. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=93306494 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jbiomech.2013.09.020 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 148 Subjects: – SubjectFull: Extracellular fluid Type: general – SubjectFull: Cartilage Type: general – SubjectFull: Tribology Type: general – SubjectFull: Biomimetic chemicals Type: general – SubjectFull: Biomechanics Type: general – SubjectFull: Osteoarthritis Type: general Titles: – TitleFull: An analytical model to predict interstitial lubrication of cartilage in migrating contact areas. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Moore, A. C. – PersonEntity: Name: NameFull: Burris, D. L. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2014 Type: published Y: 2014 Identifiers: – Type: issn-print Value: 00219290 Numbering: – Type: volume Value: 47 – Type: issue Value: 1 Titles: – TitleFull: Journal of Biomechanics Type: main |
| ResultId | 1 |
