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A high-resolution peak fractionation approach for streamlined screening of nuclear-factor-E2-related factor-2 activators in Salvia miltiorrhiza.

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Title: A high-resolution peak fractionation approach for streamlined screening of nuclear-factor-E2-related factor-2 activators in Salvia miltiorrhiza.
Authors: Zhang, Hui1, Luo, Li-Ping1, Song, Hui-Peng1, Hao, Hai-Ping1, Zhou, Ping1, Qi, Lian-Wen1, Li, Ping1 liping2004@126.com, Chen, Jun1 chenj2002@gmail.com
Source: Journal of Chromatography A. Jan2014, Vol. 1326, p47-55. 9p.
Subjects: Polymer fractionation, NF-kappa B, Salvia, Streamlines (Fluids), Bioactive compounds, High performance liquid chromatography, Diterpenes
Abstract: Highlights: [•] A universal HRPF strategy was developed for discovery of bioactive compounds. [•] This strategy realized high-purity peak fraction preparation in one HPLC run. [•] HRPF combined with a luciferase reporter gene assay to screen Nrf2 activators. [•] 20 diterpene quinones were screened out and unambiguously identified. [•] 16 compounds were reported to possess novel Nrf2 activation effect. [Copyright &y& Elsevier]
Copyright of Journal of Chromatography A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 93700901
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Label: Title
  Group: Ti
  Data: A high-resolution peak fractionation approach for streamlined screening of nuclear-factor-E2-related factor-2 activators in Salvia miltiorrhiza.
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  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Zhang%2C+Hui%22">Zhang, Hui</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Luo%2C+Li-Ping%22">Luo, Li-Ping</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Song%2C+Hui-Peng%22">Song, Hui-Peng</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Hao%2C+Hai-Ping%22">Hao, Hai-Ping</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhou%2C+Ping%22">Zhou, Ping</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Qi%2C+Lian-Wen%22">Qi, Lian-Wen</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Li%2C+Ping%22">Li, Ping</searchLink><relatesTo>1</relatesTo><i> liping2004@126.com</i><br /><searchLink fieldCode="AR" term="%22Chen%2C+Jun%22">Chen, Jun</searchLink><relatesTo>1</relatesTo><i> chenj2002@gmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Chromatography+A%22">Journal of Chromatography A</searchLink>. Jan2014, Vol. 1326, p47-55. 9p.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Polymer+fractionation%22">Polymer fractionation</searchLink><br /><searchLink fieldCode="DE" term="%22NF-kappa+B%22">NF-kappa B</searchLink><br /><searchLink fieldCode="DE" term="%22Salvia%22">Salvia</searchLink><br /><searchLink fieldCode="DE" term="%22Streamlines+%28Fluids%29%22">Streamlines (Fluids)</searchLink><br /><searchLink fieldCode="DE" term="%22Bioactive+compounds%22">Bioactive compounds</searchLink><br /><searchLink fieldCode="DE" term="%22High+performance+liquid+chromatography%22">High performance liquid chromatography</searchLink><br /><searchLink fieldCode="DE" term="%22Diterpenes%22">Diterpenes</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Highlights: [•] A universal HRPF strategy was developed for discovery of bioactive compounds. [•] This strategy realized high-purity peak fraction preparation in one HPLC run. [•] HRPF combined with a luciferase reporter gene assay to screen Nrf2 activators. [•] 20 diterpene quinones were screened out and unambiguously identified. [•] 16 compounds were reported to possess novel Nrf2 activation effect. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Chromatography A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=93700901
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.chroma.2013.12.042
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 47
    Subjects:
      – SubjectFull: Polymer fractionation
        Type: general
      – SubjectFull: NF-kappa B
        Type: general
      – SubjectFull: Salvia
        Type: general
      – SubjectFull: Streamlines (Fluids)
        Type: general
      – SubjectFull: Bioactive compounds
        Type: general
      – SubjectFull: High performance liquid chromatography
        Type: general
      – SubjectFull: Diterpenes
        Type: general
    Titles:
      – TitleFull: A high-resolution peak fractionation approach for streamlined screening of nuclear-factor-E2-related factor-2 activators in Salvia miltiorrhiza.
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Zhang, Hui
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            NameFull: Luo, Li-Ping
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            NameFull: Song, Hui-Peng
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            NameFull: Hao, Hai-Ping
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            NameFull: Zhou, Ping
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            NameFull: Qi, Lian-Wen
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            NameFull: Li, Ping
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            NameFull: Chen, Jun
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            – D: 24
              M: 01
              Text: Jan2014
              Type: published
              Y: 2014
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              Value: 00219673
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            – Type: volume
              Value: 1326
          Titles:
            – TitleFull: Journal of Chromatography A
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