Delta22-ursodeoxycholic acid, a unique metabolite of administered ursodeoxycholic acid in rats...

Saved in:
Bibliographic Details
Title: Delta22-ursodeoxycholic acid, a unique metabolite of administered ursodeoxycholic acid in rats...
Authors: Setchell, Kenneth D.R., Yamashita, Hiroyuki
Source: Biochemistry. 4/4/95, Vol. 34 Issue 13, p4169. 10p. 1 Diagram, 2 Charts, 16 Graphs.
Subjects: Ursodeoxycholic acid, Metabolism
Abstract: Describes the identification of delta22-ursodeoxycholic acid in the plasma, bile, intestinal contents and liver tissue of Sprague-Dawley rats after intravenous and oral administration of ursodeoxycholic acid (UDCA). Establishment of a definitive conformation of the metabolite; Quantification of delta22-UDCA and side-chain unsaturated bile acids.
Database: Engineering Source
Description
Abstract:Describes the identification of delta22-ursodeoxycholic acid in the plasma, bile, intestinal contents and liver tissue of Sprague-Dawley rats after intravenous and oral administration of ursodeoxycholic acid (UDCA). Establishment of a definitive conformation of the metabolite; Quantification of delta22-UDCA and side-chain unsaturated bile acids.
ISSN:00062960
DOI:10.1021/bi00013a004