Analysis of the effect of phototherapy in model with traumatic Achilles tendon injury in rats.
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| Title: | Analysis of the effect of phototherapy in model with traumatic Achilles tendon injury in rats. |
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| Authors: | Casalechi, Heliodora1, de Farias Marques, Anna1, da Silva, Evela1, Aimbire, Flávio2, Marcos, Rodrigo3, Lopes-Martins, Rodrigo3, de Carvalho, Paulo1, Albertini, Regiane1 regianealbertini@uninove.br |
| Source: | Lasers in Medical Science. May2014, Vol. 29 Issue 3, p1075-1081. 7p. |
| Subjects: | Achilles tendon injury treatment, Tendinitis treatment, Phototherapy, Laser therapy, Collagen, Biomechanics, Cell migration |
| Abstract: | The aim of this study was to investigate the effect of low-intensity laser (LILT) infrared (830 nm) therapy in tendon inflammation, tendinitis induced by mechanical trauma in rat Achilles tendon. For this, we used 65 young male Wistar rats, weighing ±300 g divided into different groups: C = control ( n = 5) and experimental ( n = 10/group), with two different times of sacrifice such as treated with L = laser, D = treated with diclofenac, and T = untreated injured. The tendon inflammation was induced by controlled contusion in the medial region of the Achilles tendon of the animals. The treated groups received some kind of intervention every 24 h, all groups were sacrificed on the 7th or 14th day after the trauma. The tendons were dissected, extracted, and sent for analysis. Histological analysis of the L group showed a decrease in the number of inflammatory cells in relation to other groups in both periods studied. The comparative results between the number of inflammatory cells in the control and treated groups at 7 and 14 days showed statistically significant differences. Qualitative analysis findings obtained by the picrosirius red technique under polarized light showed that in 7 days, the T group presented collagen types I and III in the same proportion; group D presented a predominance of type III fibers, while in group L, type I collagen predominated. The 14-day group D showed collagen types I and III in the same proportion, while in group L, there was a predominance of type I fibers. Biomechanical analysis showed that 7-day groups L and C showed similar stiffness and increased breaking strength. The 14-day groups L and C showed greater rupturing strength as well as increased stiffness angle. Group D showed a decrease of maximum traction strength and degree of rigidity. It was concluded that treatment with LIL in the parameters used and the times studied reduces migration of inflammatory cells and improves the quality of repair while reducing the functional limitations. [ABSTRACT FROM AUTHOR] |
| Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 96152091 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Analysis of the effect of phototherapy in model with traumatic Achilles tendon injury in rats. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Casalechi%2C+Heliodora%22">Casalechi, Heliodora</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22de+Farias+Marques%2C+Anna%22">de Farias Marques, Anna</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22da+Silva%2C+Evela%22">da Silva, Evela</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Aimbire%2C+Flávio%22">Aimbire, Flávio</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Marcos%2C+Rodrigo%22">Marcos, Rodrigo</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Lopes-Martins%2C+Rodrigo%22">Lopes-Martins, Rodrigo</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22de+Carvalho%2C+Paulo%22">de Carvalho, Paulo</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Albertini%2C+Regiane%22">Albertini, Regiane</searchLink><relatesTo>1</relatesTo><i> regianealbertini@uninove.br</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lasers+in+Medical+Science%22">Lasers in Medical Science</searchLink>. May2014, Vol. 29 Issue 3, p1075-1081. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Achilles+tendon+injury+treatment%22">Achilles tendon injury treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Tendinitis+treatment%22">Tendinitis treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Phototherapy%22">Phototherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Laser+therapy%22">Laser therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Collagen%22">Collagen</searchLink><br /><searchLink fieldCode="DE" term="%22Biomechanics%22">Biomechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+migration%22">Cell migration</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The aim of this study was to investigate the effect of low-intensity laser (LILT) infrared (830 nm) therapy in tendon inflammation, tendinitis induced by mechanical trauma in rat Achilles tendon. For this, we used 65 young male Wistar rats, weighing ±300 g divided into different groups: C = control ( n = 5) and experimental ( n = 10/group), with two different times of sacrifice such as treated with L = laser, D = treated with diclofenac, and T = untreated injured. The tendon inflammation was induced by controlled contusion in the medial region of the Achilles tendon of the animals. The treated groups received some kind of intervention every 24 h, all groups were sacrificed on the 7th or 14th day after the trauma. The tendons were dissected, extracted, and sent for analysis. Histological analysis of the L group showed a decrease in the number of inflammatory cells in relation to other groups in both periods studied. The comparative results between the number of inflammatory cells in the control and treated groups at 7 and 14 days showed statistically significant differences. Qualitative analysis findings obtained by the picrosirius red technique under polarized light showed that in 7 days, the T group presented collagen types I and III in the same proportion; group D presented a predominance of type III fibers, while in group L, type I collagen predominated. The 14-day group D showed collagen types I and III in the same proportion, while in group L, there was a predominance of type I fibers. Biomechanical analysis showed that 7-day groups L and C showed similar stiffness and increased breaking strength. The 14-day groups L and C showed greater rupturing strength as well as increased stiffness angle. Group D showed a decrease of maximum traction strength and degree of rigidity. It was concluded that treatment with LIL in the parameters used and the times studied reduces migration of inflammatory cells and improves the quality of repair while reducing the functional limitations. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10103-013-1468-1 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 1075 Subjects: – SubjectFull: Achilles tendon injury treatment Type: general – SubjectFull: Tendinitis treatment Type: general – SubjectFull: Phototherapy Type: general – SubjectFull: Laser therapy Type: general – SubjectFull: Collagen Type: general – SubjectFull: Biomechanics Type: general – SubjectFull: Cell migration Type: general Titles: – TitleFull: Analysis of the effect of phototherapy in model with traumatic Achilles tendon injury in rats. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Casalechi, Heliodora – PersonEntity: Name: NameFull: de Farias Marques, Anna – PersonEntity: Name: NameFull: da Silva, Evela – PersonEntity: Name: NameFull: Aimbire, Flávio – PersonEntity: Name: NameFull: Marcos, Rodrigo – PersonEntity: Name: NameFull: Lopes-Martins, Rodrigo – PersonEntity: Name: NameFull: de Carvalho, Paulo – PersonEntity: Name: NameFull: Albertini, Regiane IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2014 Type: published Y: 2014 Identifiers: – Type: issn-print Value: 02688921 Numbering: – Type: volume Value: 29 – Type: issue Value: 3 Titles: – TitleFull: Lasers in Medical Science Type: main |
| ResultId | 1 |
