Protection of the hydroxyphosphinyl function of phosphinic dipeptides by adamantyl. Application...

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Bibliographic Details
Title: Protection of the hydroxyphosphinyl function of phosphinic dipeptides by adamantyl. Application...
Authors: Yiotakis, Athanasios, Vassiliou, Stamatia
Source: Journal of Organic Chemistry. 9/20/96, Vol. 61 Issue 19, p6601. 5p. 4 Diagrams, 4 Charts, 4 Graphs.
Subjects: Phosphine, Solid-phase synthesis
Abstract: Presents a methodology for the protection of hydroxyphosphinyl function of phosphinic dipeptides by the adamantyl group. Solid-phase synthesis of phosphinic peptides; Use of methodology in facilitation of zinc-metalloproteases inhibitors; Stability of phosphinic adamantyl esters.
Database: Engineering Source
Description
Abstract:Presents a methodology for the protection of hydroxyphosphinyl function of phosphinic dipeptides by the adamantyl group. Solid-phase synthesis of phosphinic peptides; Use of methodology in facilitation of zinc-metalloproteases inhibitors; Stability of phosphinic adamantyl esters.
ISSN:00223263
DOI:10.1021/jo9603439