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Prospective evaluation of concurrent meniscus transplantation and articular cartilage repair: minimum 2-year follow-up.

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Title: Prospective evaluation of concurrent meniscus transplantation and articular cartilage repair: minimum 2-year follow-up.
Authors: Rue JH (AUTHOR), Yanke AB (AUTHOR), Busam ML (AUTHOR), McNickle AG (AUTHOR), Cole BJ (AUTHOR)
Source: American Journal of Sports Medicine. Sep2008, Vol. 36 Issue 9, p1770-1778. 9p.
Abstract: Background: Recognition of the symbiotic relationship between the meniscus and articular cartilage is critical to the success of meniscal allograft transplantation. Simultaneous combined meniscal allograft transplantation and cartilage restoration procedures have been proposed for patients with a symptomatic postmeniscectomy knee with a focal chondral defect that would have traditionally been considered a contraindication to meniscal allograft transplantation.Hypothesis: Combined meniscal allograft transplantation and cartilage restoration procedures can be used to neutralize traditional contraindications to meniscal allograft transplantation with results comparable to either procedure performed in isolation.Study Design: Case series; Level of evidence, 4.Methods: Thirty patients underwent 31 combined meniscal allograft transplantation and cartilage restoration procedures between 1997 and 2004. These patients were prospectively studied, and completed standardized outcome surveys (including Lysholm, International Knee Documentation Committee, and Short Form-12 scales) preoperatively and annually thereafter for a minimum of 2-year follow-up. Patients were grouped according to concomitant procedure: 16 (52%) underwent meniscal allograft transplantation combined with autologous chondrocyte implantation; 15 (48%) had meniscal allograft transplantation combined with an osteochondral allograft. Two patients were lost to follow-up, leaving 29 procedures for review.Results: As a combined group, statistically significant improvements were observed in all standardized outcomes scores and satisfaction scales, except Short Form-12 mental, at a mean 3.1-year follow-up. Excluding the 2 lost to follow-up, 76% of all study participants (80% autologous chondrocyte implantation; 71% osteochondral allograft) reported that they were completely (31%) or mostly (45%) satisfied with their results. Overall, 48% of patients (60% autologous chondrocyte implantation; 36% osteochondral allograft) were classified as normal or nearly normal at their most recent follow-up using the International Knee Documentation Committee examination score. Ninety percent of patients would have the surgery again.Conclusion: Combined meniscal allograft transplantation and cartilage restoration offers a safe alternative for patients with persistent symptoms after meniscectomy and focal cartilage injury. Results of combined procedures were comparable to published reports of these procedures performed in isolation. Long-term follow-up is needed to define the survivorship of these procedures in a young patient population. [ABSTRACT FROM AUTHOR]
Copyright of American Journal of Sports Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Prospective evaluation of concurrent meniscus transplantation and articular cartilage repair: minimum 2-year follow-up.
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  Data: <searchLink fieldCode="AR" term="%22Rue+JH%22">Rue JH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yanke+AB%22">Yanke AB</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Busam+ML%22">Busam ML</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22McNickle+AG%22">McNickle AG</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cole+BJ%22">Cole BJ</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22American+Journal+of+Sports+Medicine%22">American Journal of Sports Medicine</searchLink>. Sep2008, Vol. 36 Issue 9, p1770-1778. 9p.
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Recognition of the symbiotic relationship between the meniscus and articular cartilage is critical to the success of meniscal allograft transplantation. Simultaneous combined meniscal allograft transplantation and cartilage restoration procedures have been proposed for patients with a symptomatic postmeniscectomy knee with a focal chondral defect that would have traditionally been considered a contraindication to meniscal allograft transplantation.Hypothesis: Combined meniscal allograft transplantation and cartilage restoration procedures can be used to neutralize traditional contraindications to meniscal allograft transplantation with results comparable to either procedure performed in isolation.Study Design: Case series; Level of evidence, 4.Methods: Thirty patients underwent 31 combined meniscal allograft transplantation and cartilage restoration procedures between 1997 and 2004. These patients were prospectively studied, and completed standardized outcome surveys (including Lysholm, International Knee Documentation Committee, and Short Form-12 scales) preoperatively and annually thereafter for a minimum of 2-year follow-up. Patients were grouped according to concomitant procedure: 16 (52%) underwent meniscal allograft transplantation combined with autologous chondrocyte implantation; 15 (48%) had meniscal allograft transplantation combined with an osteochondral allograft. Two patients were lost to follow-up, leaving 29 procedures for review.Results: As a combined group, statistically significant improvements were observed in all standardized outcomes scores and satisfaction scales, except Short Form-12 mental, at a mean 3.1-year follow-up. Excluding the 2 lost to follow-up, 76% of all study participants (80% autologous chondrocyte implantation; 71% osteochondral allograft) reported that they were completely (31%) or mostly (45%) satisfied with their results. Overall, 48% of patients (60% autologous chondrocyte implantation; 36% osteochondral allograft) were classified as normal or nearly normal at their most recent follow-up using the International Knee Documentation Committee examination score. Ninety percent of patients would have the surgery again.Conclusion: Combined meniscal allograft transplantation and cartilage restoration offers a safe alternative for patients with persistent symptoms after meniscectomy and focal cartilage injury. Results of combined procedures were comparable to published reports of these procedures performed in isolation. Long-term follow-up is needed to define the survivorship of these procedures in a young patient population. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of American Journal of Sports Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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