The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis.
Saved in:
| Title: | The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. |
|---|---|
| Authors: | Lohmander LS (AUTHOR), Englund PM (AUTHOR), Dahl LL (AUTHOR), Roos EM (AUTHOR) |
| Source: | American Journal of Sports Medicine. Oct2007, Vol. 35 Issue 10, p1756-1769. 14p. |
| Abstract: | The objectives of this study are to review the long-term consequences of injuries to the anterior cruciate ligament and menisci, the pathogenic mechanisms, and the causes of the considerable variability in outcome. Injuries of the anterior cruciate ligament and menisci are common in both athletes and the general population. At 10 to 20 years after the diagnosis, on average, 50% of those with a diagnosed anterior cruciate ligament or meniscus tear have osteoarthritis with associated pain and functional impairment: the young patient with an old knee. These individuals make up a substantial proportion of the overall osteoarthritis population. There is a lack of evidence to support a protective role of repair or reconstructive surgery of the anterior cruciate ligament or meniscus against osteoarthritis development. A consistent finding in a review of the literature is the often poor reporting of critical study variables, precluding data pooling or a meta-analysis. Osteoarthritis development in the injured joints is caused by intra-articular pathogenic processes initiated at the time of injury, combined with long-term changes in dynamic joint loading. Variation in outcome is reinforced by additional variables associated with the individual such as age, sex, genetics, obesity, muscle strength, activity, and reinjury. A better understanding of these variables may improve future prevention and treatment strategies. In evaluating medical treatment, we now expect large randomized clinical trials complemented by postmarketing monitoring. We should strive toward a comparable level of quality of evidence in surgical treatment of knee injuries. In instances in which a randomized clinical trial is not feasible, natural history and other observational cohort studies need to be as carefully designed and reported as the classic randomized clinical trial, to yield useful information. [ABSTRACT FROM AUTHOR] |
| Copyright of American Journal of Sports Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Education Research Complete |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: ehh DbLabel: Education Research Complete An: 106001433 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Lohmander+LS%22">Lohmander LS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Englund+PM%22">Englund PM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dahl+LL%22">Dahl LL</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Roos+EM%22">Roos EM</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22American+Journal+of+Sports+Medicine%22">American Journal of Sports Medicine</searchLink>. Oct2007, Vol. 35 Issue 10, p1756-1769. 14p. – Name: Abstract Label: Abstract Group: Ab Data: The objectives of this study are to review the long-term consequences of injuries to the anterior cruciate ligament and menisci, the pathogenic mechanisms, and the causes of the considerable variability in outcome. Injuries of the anterior cruciate ligament and menisci are common in both athletes and the general population. At 10 to 20 years after the diagnosis, on average, 50% of those with a diagnosed anterior cruciate ligament or meniscus tear have osteoarthritis with associated pain and functional impairment: the young patient with an old knee. These individuals make up a substantial proportion of the overall osteoarthritis population. There is a lack of evidence to support a protective role of repair or reconstructive surgery of the anterior cruciate ligament or meniscus against osteoarthritis development. A consistent finding in a review of the literature is the often poor reporting of critical study variables, precluding data pooling or a meta-analysis. Osteoarthritis development in the injured joints is caused by intra-articular pathogenic processes initiated at the time of injury, combined with long-term changes in dynamic joint loading. Variation in outcome is reinforced by additional variables associated with the individual such as age, sex, genetics, obesity, muscle strength, activity, and reinjury. A better understanding of these variables may improve future prevention and treatment strategies. In evaluating medical treatment, we now expect large randomized clinical trials complemented by postmarketing monitoring. We should strive toward a comparable level of quality of evidence in surgical treatment of knee injuries. In instances in which a randomized clinical trial is not feasible, natural history and other observational cohort studies need to be as carefully designed and reported as the classic randomized clinical trial, to yield useful information. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of American Journal of Sports Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=ehh&AN=106001433 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1177/0363546507307396 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 14 StartPage: 1756 Titles: – TitleFull: The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lohmander LS – PersonEntity: Name: NameFull: Englund PM – PersonEntity: Name: NameFull: Dahl LL – PersonEntity: Name: NameFull: Roos EM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2007 Type: published Y: 2007 Identifiers: – Type: issn-print Value: 03635465 Numbering: – Type: volume Value: 35 – Type: issue Value: 10 Titles: – TitleFull: American Journal of Sports Medicine Type: main |
| ResultId | 1 |
