The effect of botulinum toxin type-A injection on spasticity, range of motion and gait patterns in children with spastic diplegic cerebral palsy: an Egyptian study.
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| Title: | The effect of botulinum toxin type-A injection on spasticity, range of motion and gait patterns in children with spastic diplegic cerebral palsy: an Egyptian study. |
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| Authors: | El-Etribi MA (AUTHOR), Salem ME (AUTHOR), El-Shakankiry HM (AUTHOR), El-Kahky AM (AUTHOR), El-Mahboub SM (AUTHOR) |
| Source: | International Journal of Rehabilitation Research. Dec2004, Vol. 27 Issue 4, p275-281. 7p. |
| Abstract: | Spasticity is defined as increased resistance to passive movement, secondary to hyperreflexia after an upper motor neuron lesion. In children with cerebral palsy (CP), it can interfere with mobility and self-care and can contribute to development of fixed myostatic contractures. This study investigated the efficacy of botulinum toxin type-A, a neuromuscular blocking agent that reduces muscle tone, in a variety of neuromuscular disorders, injections in a prospective, 3-month, controlled study involving 40 children with spastic diplegic CP. The patients were divided into two groups: Group 1 (20 patients) entered a botulinum toxin type-A injection+physiotherapy rehabilitation program; Group 2 (20 patients) were given the physiotherapy rehabilitation program only. Patients were assessed at 4, 8 and 12 weeks post-treatment using the Modified Ashworth Scale (MAS), dynamic gait pattern, ankle range-of-motion measurements and quantification of muscle denervation by nerve conduction techniques. The botulinum toxin type-A group demonstrated statistically significantly decreased spasticity, improved gait function and improved range of motion with evidence of partial denervation of the injected muscle compared to the control group. In conclusion, botulinum toxin type-A injections are a well-tolerated, non-surgical technique that can improve overall response to physiotherapy. [ABSTRACT FROM AUTHOR] |
| Copyright of International Journal of Rehabilitation Research is the property of Lippincott Williams & Wilkins and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Education Research Complete |
| FullText | Text: Availability: 0 |
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| Header | DbId: ehh DbLabel: Education Research Complete An: 106486726 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The effect of botulinum toxin type-A injection on spasticity, range of motion and gait patterns in children with spastic diplegic cerebral palsy: an Egyptian study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22El-Etribi+MA%22">El-Etribi MA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Salem+ME%22">Salem ME</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22El-Shakankiry+HM%22">El-Shakankiry HM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22El-Kahky+AM%22">El-Kahky AM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22El-Mahboub+SM%22">El-Mahboub SM</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Rehabilitation+Research%22">International Journal of Rehabilitation Research</searchLink>. Dec2004, Vol. 27 Issue 4, p275-281. 7p. – Name: Abstract Label: Abstract Group: Ab Data: Spasticity is defined as increased resistance to passive movement, secondary to hyperreflexia after an upper motor neuron lesion. In children with cerebral palsy (CP), it can interfere with mobility and self-care and can contribute to development of fixed myostatic contractures. This study investigated the efficacy of botulinum toxin type-A, a neuromuscular blocking agent that reduces muscle tone, in a variety of neuromuscular disorders, injections in a prospective, 3-month, controlled study involving 40 children with spastic diplegic CP. The patients were divided into two groups: Group 1 (20 patients) entered a botulinum toxin type-A injection+physiotherapy rehabilitation program; Group 2 (20 patients) were given the physiotherapy rehabilitation program only. Patients were assessed at 4, 8 and 12 weeks post-treatment using the Modified Ashworth Scale (MAS), dynamic gait pattern, ankle range-of-motion measurements and quantification of muscle denervation by nerve conduction techniques. The botulinum toxin type-A group demonstrated statistically significantly decreased spasticity, improved gait function and improved range of motion with evidence of partial denervation of the injected muscle compared to the control group. In conclusion, botulinum toxin type-A injections are a well-tolerated, non-surgical technique that can improve overall response to physiotherapy. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of International Journal of Rehabilitation Research is the property of Lippincott Williams & Wilkins and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1097/00004356-200412000-00004 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 275 Titles: – TitleFull: The effect of botulinum toxin type-A injection on spasticity, range of motion and gait patterns in children with spastic diplegic cerebral palsy: an Egyptian study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: El-Etribi MA – PersonEntity: Name: NameFull: Salem ME – PersonEntity: Name: NameFull: El-Shakankiry HM – PersonEntity: Name: NameFull: El-Kahky AM – PersonEntity: Name: NameFull: El-Mahboub SM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2004 Type: published Y: 2004 Identifiers: – Type: issn-print Value: 03425282 Numbering: – Type: volume Value: 27 – Type: issue Value: 4 Titles: – TitleFull: International Journal of Rehabilitation Research Type: main |
| ResultId | 1 |
