Exercise responses of elderly patients with diastolic versus systolic heart failure.
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| Title: | Exercise responses of elderly patients with diastolic versus systolic heart failure. |
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| Authors: | Brubaker PH (AUTHOR), Marburger CT (AUTHOR), Morgan TM (AUTHOR), Fray B (AUTHOR), Kitzman DW (AUTHOR) |
| Source: | Medicine & Science in Sports & Exercise. Sep2003, Vol. 35 Issue 9, p1477-1485. 9p. |
| Abstract: | PURPOSE: Little information is available regarding peak and submaximal exercise performance in elderly heart failure (HF) patients, particularly in those with diastolic dysfunction (DD). Therefore, the purpose of this investigation was to compare exercise responses of elderly patients with HF due to either systolic dysfunction (SD) or DD, to age-matched healthy volunteers (HV). METHODS: Patients with chronic HF > or = 60 yr (N = 119) due to SD (N = 60) or primary DD (N = 59) underwent a maximal cycle ergometry test with expired gas analysis and venous lactate measurement. Twenty-eight HV > or = 60 yr served as a control group. Anaerobic threshold was determined by gas analysis (ATVEN) and by plasma lactate rise (ATLAC). RESULTS: Peak oxygen consumption (VO(2peak)) was significantly (P < 0.001) reduced in both SD and DD patients (13 +/- 0.4 vs 14 +/- 0.4 ml x kg(-1) x min(-1), respectively) versus HV (20 +/- 0.6 ml x kg(-1) x min(-1)). Peak heart rate was reduced in patients versus HV (131 +/- 3 bpm vs 145 +/- 4, respectively; P < or = 0.01), but heart rate at a given submaximal work rate was significantly lower (P < or = 0.01) in HV than in SD and DD patients. ATVEN of 11.8 +/- 0.3 ml x kg(-1) x min(-1) for HV was significantly higher than SD (8.9 +/- 0.2) and DD (9.2 +/- 0.3). Peak lactate concentration was 6.6 +/- 0.6 mmol x kg(-1) x l(-1) in HV and was significantly reduced in both SD and DD HF patients. ATVEN correlated well with ATLAC in HV and in DD patients, but not in SD patients. CONCLUSIONS: Submaximal and peak exercise performance are markedly altered in elderly HF patients compared with age-matched HV but do not appear to be different between SD and DD patients. [ABSTRACT FROM AUTHOR] |
| Copyright of Medicine & Science in Sports & Exercise is the property of Lippincott Williams & Wilkins and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Education Research Complete |
| FullText | Text: Availability: 0 |
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| Header | DbId: ehh DbLabel: Education Research Complete An: 106730191 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Exercise responses of elderly patients with diastolic versus systolic heart failure. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Brubaker+PH%22">Brubaker PH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marburger+CT%22">Marburger CT</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Morgan+TM%22">Morgan TM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fray+B%22">Fray B</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kitzman+DW%22">Kitzman DW</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medicine+%26+Science+in+Sports+%26+Exercise%22">Medicine & Science in Sports & Exercise</searchLink>. Sep2003, Vol. 35 Issue 9, p1477-1485. 9p. – Name: Abstract Label: Abstract Group: Ab Data: PURPOSE: Little information is available regarding peak and submaximal exercise performance in elderly heart failure (HF) patients, particularly in those with diastolic dysfunction (DD). Therefore, the purpose of this investigation was to compare exercise responses of elderly patients with HF due to either systolic dysfunction (SD) or DD, to age-matched healthy volunteers (HV). METHODS: Patients with chronic HF > or = 60 yr (N = 119) due to SD (N = 60) or primary DD (N = 59) underwent a maximal cycle ergometry test with expired gas analysis and venous lactate measurement. Twenty-eight HV > or = 60 yr served as a control group. Anaerobic threshold was determined by gas analysis (ATVEN) and by plasma lactate rise (ATLAC). RESULTS: Peak oxygen consumption (VO(2peak)) was significantly (P < 0.001) reduced in both SD and DD patients (13 +/- 0.4 vs 14 +/- 0.4 ml x kg(-1) x min(-1), respectively) versus HV (20 +/- 0.6 ml x kg(-1) x min(-1)). Peak heart rate was reduced in patients versus HV (131 +/- 3 bpm vs 145 +/- 4, respectively; P < or = 0.01), but heart rate at a given submaximal work rate was significantly lower (P < or = 0.01) in HV than in SD and DD patients. ATVEN of 11.8 +/- 0.3 ml x kg(-1) x min(-1) for HV was significantly higher than SD (8.9 +/- 0.2) and DD (9.2 +/- 0.3). Peak lactate concentration was 6.6 +/- 0.6 mmol x kg(-1) x l(-1) in HV and was significantly reduced in both SD and DD HF patients. ATVEN correlated well with ATLAC in HV and in DD patients, but not in SD patients. CONCLUSIONS: Submaximal and peak exercise performance are markedly altered in elderly HF patients compared with age-matched HV but do not appear to be different between SD and DD patients. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medicine & Science in Sports & Exercise is the property of Lippincott Williams & Wilkins and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1249/01.mss.0000084416.71232.ea Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 1477 Titles: – TitleFull: Exercise responses of elderly patients with diastolic versus systolic heart failure. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Brubaker PH – PersonEntity: Name: NameFull: Marburger CT – PersonEntity: Name: NameFull: Morgan TM – PersonEntity: Name: NameFull: Fray B – PersonEntity: Name: NameFull: Kitzman DW IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep2003 Type: published Y: 2003 Identifiers: – Type: issn-print Value: 01959131 Numbering: – Type: volume Value: 35 – Type: issue Value: 9 Titles: – TitleFull: Medicine & Science in Sports & Exercise Type: main |
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