Birth Defects Associated With Congenital Zika Virus Infection in Mexico.
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| Title: | Birth Defects Associated With Congenital Zika Virus Infection in Mexico. |
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| Authors: | Contreras-Capetillo, Silvina Noemí1,2 silvina.contreras@correo.uady.mx, Valadéz-González, Nina2, Manrique-Saide, Pablo3, Carcaño-Castillo, Rafael Eduardo2, Pacheco-Tugores, Freddy1, Moshe Barrera-Pérez, Hirian Alonso4, Pinto-Escalante, Doris2, Lliteras-Cardín, Manuel1, Hoil-Parra, José Alfredo1, Cáceres-Solís, José Luis5, Pavía-Ruz, Norma2 |
| Source: | Clinical Pediatrics. Jul2018, Vol. 57 Issue 8, p927-936. 10p. |
| Subject Terms: | Diagnosis of brain diseases, Fetal growth retardation, Human abnormalities, Polymerase chain reaction, RNA, Calcinosis, Zika virus infections, Disease complications, Diagnosis |
| Geographic Terms: | Mexico |
| Abstract: | Part of the work agenda of international health authorities is to define the clinical spectrum of the congenital Zika syndrome (CZS) in different territories. We describe the clinical variability that gave rise to the suspicion of CZS in 3 newborn patients in the south of Mexico with active transmission of Zika. All of them presented Zika RNA by reverse transcription-polymerase chain reaction and positive antibodies for IgM by enzyme-linked immunosorbent assay. None of the mothers tested positive for active viremia, only one mother had Zika-symptoms and titers of Zika-positive IgM. Intrauterine growth restriction, brain disruption sequence, and intracranial calcifications are the clinical characteristics common in all. One patient had neural tube defect and other, arthrogryposis. Because the majority of pregnant women will be asymptomatic to Zika, we must be alert to the clinical variability of the birth defects associated to pregnancy Zika infection. Reports of clinical cases encourage the medical community to make diagnostic decisions. [ABSTRACT FROM AUTHOR] |
| Copyright of Clinical Pediatrics is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Education Research Complete |
| FullText | Text: Availability: 0 |
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| Header | DbId: ehh DbLabel: Education Research Complete An: 130020159 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Birth Defects Associated With Congenital Zika Virus Infection in Mexico. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Contreras-Capetillo%2C+Silvina+Noemí%22">Contreras-Capetillo, Silvina Noemí</searchLink><relatesTo>1,2</relatesTo><i> silvina.contreras@correo.uady.mx</i><br /><searchLink fieldCode="AR" term="%22Valadéz-González%2C+Nina%22">Valadéz-González, Nina</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Manrique-Saide%2C+Pablo%22">Manrique-Saide, Pablo</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Carcaño-Castillo%2C+Rafael+Eduardo%22">Carcaño-Castillo, Rafael Eduardo</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Pacheco-Tugores%2C+Freddy%22">Pacheco-Tugores, Freddy</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Moshe+Barrera-Pérez%2C+Hirian+Alonso%22">Moshe Barrera-Pérez, Hirian Alonso</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Pinto-Escalante%2C+Doris%22">Pinto-Escalante, Doris</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Lliteras-Cardín%2C+Manuel%22">Lliteras-Cardín, Manuel</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Hoil-Parra%2C+José+Alfredo%22">Hoil-Parra, José Alfredo</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Cáceres-Solís%2C+José+Luis%22">Cáceres-Solís, José Luis</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Pavía-Ruz%2C+Norma%22">Pavía-Ruz, Norma</searchLink><relatesTo>2</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Clinical+Pediatrics%22">Clinical Pediatrics</searchLink>. Jul2018, Vol. 57 Issue 8, p927-936. 10p. – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Diagnosis+of+brain+diseases%22">Diagnosis of brain diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Fetal+growth+retardation%22">Fetal growth retardation</searchLink><br /><searchLink fieldCode="DE" term="%22Human+abnormalities%22">Human abnormalities</searchLink><br /><searchLink fieldCode="DE" term="%22Polymerase+chain+reaction%22">Polymerase chain reaction</searchLink><br /><searchLink fieldCode="DE" term="%22RNA%22">RNA</searchLink><br /><searchLink fieldCode="DE" term="%22Calcinosis%22">Calcinosis</searchLink><br /><searchLink fieldCode="DE" term="%22Zika+virus+infections%22">Zika virus infections</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+complications%22">Disease complications</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis%22">Diagnosis</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Mexico%22">Mexico</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Part of the work agenda of international health authorities is to define the clinical spectrum of the congenital Zika syndrome (CZS) in different territories. We describe the clinical variability that gave rise to the suspicion of CZS in 3 newborn patients in the south of Mexico with active transmission of Zika. All of them presented Zika RNA by reverse transcription-polymerase chain reaction and positive antibodies for IgM by enzyme-linked immunosorbent assay. None of the mothers tested positive for active viremia, only one mother had Zika-symptoms and titers of Zika-positive IgM. Intrauterine growth restriction, brain disruption sequence, and intracranial calcifications are the clinical characteristics common in all. One patient had neural tube defect and other, arthrogryposis. Because the majority of pregnant women will be asymptomatic to Zika, we must be alert to the clinical variability of the birth defects associated to pregnancy Zika infection. Reports of clinical cases encourage the medical community to make diagnostic decisions. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Clinical Pediatrics is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1177/0009922817738341 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 927 Subjects: – SubjectFull: Diagnosis of brain diseases Type: general – SubjectFull: Fetal growth retardation Type: general – SubjectFull: Human abnormalities Type: general – SubjectFull: Polymerase chain reaction Type: general – SubjectFull: RNA Type: general – SubjectFull: Calcinosis Type: general – SubjectFull: Zika virus infections Type: general – SubjectFull: Disease complications Type: general – SubjectFull: Diagnosis Type: general – SubjectFull: Mexico Type: general Titles: – TitleFull: Birth Defects Associated With Congenital Zika Virus Infection in Mexico. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Contreras-Capetillo, Silvina Noemí – PersonEntity: Name: NameFull: Valadéz-González, Nina – PersonEntity: Name: NameFull: Manrique-Saide, Pablo – PersonEntity: Name: NameFull: Carcaño-Castillo, Rafael Eduardo – PersonEntity: Name: NameFull: Pacheco-Tugores, Freddy – PersonEntity: Name: NameFull: Moshe Barrera-Pérez, Hirian Alonso – PersonEntity: Name: NameFull: Pinto-Escalante, Doris – PersonEntity: Name: NameFull: Lliteras-Cardín, Manuel – PersonEntity: Name: NameFull: Hoil-Parra, José Alfredo – PersonEntity: Name: NameFull: Cáceres-Solís, José Luis – PersonEntity: Name: NameFull: Pavía-Ruz, Norma IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: Jul2018 Type: published Y: 2018 Identifiers: – Type: issn-print Value: 00099228 Numbering: – Type: volume Value: 57 – Type: issue Value: 8 Titles: – TitleFull: Clinical Pediatrics Type: main |
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