Acute corneal hydrops of presumed traumatic origin: An uncontrolled case series (three horses).

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Title: Acute corneal hydrops of presumed traumatic origin: An uncontrolled case series (three horses).
Authors: O'Leary, L. M.1 (AUTHOR) loleary@iastate.edu, Sebbag, L.1 (AUTHOR), Moody, L. M.2,3 (AUTHOR), Diehl, K. A.2 (AUTHOR), Allbaugh, R. A.1 (AUTHOR)
Source: Equine Veterinary Education. Jan2022, Vol. 34 Issue 1, pe11-e15. 5p.
Subject Terms: Cornea, Edema, Hypertonic saline solutions, Horses, Iridocyclitis, Pathologic neovascularization, Felidae
Abstract: Summary: This case series describes acute corneal hydrops in three young horses. Due to similarities in the clinical appearance and progression of the disease with that which is reported in humans and cats with acute corneal hydrops, traumatic Descemet's membrane rupture was suspected to be the underlying aetiology in these equine cases. The horses presented with acute severe corneal oedema with intrastromal bullae formation and anterior bulging of the corneal contour. Focal posterior corneal changes were also seen in two of three cases. Mild anterior uveitis was also present. Other causes of corneal oedema (e.g. glaucoma) were ruled out based on presentation and clinical examination. Treatment approaches were medical and included various combinations of prophylactic topical antimicrobial therapy in case of secondary corneal ulceration, anti‐inflammatory therapy for uveitis, targeted oedema therapy with topical hypertonic saline and corneal cross‐linking, and placement of a temporary partial tarsorrhaphy for corneal tamponade. The outcome was excellent in all cases, with rapid resolution of the ocular changes. Acute corneal hydrops of presumed traumatic Descemet's membrane rupture origin should be considered in cases of young horses presenting with acute corneal oedema. However, further studies are warranted to better characterise the disease and to try to confirm the suspected aetiology. [ABSTRACT FROM AUTHOR]
Copyright of Equine Veterinary Education is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Acute corneal hydrops of presumed traumatic origin: An uncontrolled case series (three horses).
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  Data: <searchLink fieldCode="AR" term="%22O'Leary%2C+L%2E+M%2E%22">O'Leary, L. M.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> loleary@iastate.edu</i><br /><searchLink fieldCode="AR" term="%22Sebbag%2C+L%2E%22">Sebbag, L.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Moody%2C+L%2E+M%2E%22">Moody, L. M.</searchLink><relatesTo>2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Diehl%2C+K%2E+A%2E%22">Diehl, K. A.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Allbaugh%2C+R%2E+A%2E%22">Allbaugh, R. A.</searchLink><relatesTo>1</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Equine+Veterinary+Education%22">Equine Veterinary Education</searchLink>. Jan2022, Vol. 34 Issue 1, pe11-e15. 5p.
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  Data: <searchLink fieldCode="DE" term="%22Cornea%22">Cornea</searchLink><br /><searchLink fieldCode="DE" term="%22Edema%22">Edema</searchLink><br /><searchLink fieldCode="DE" term="%22Hypertonic+saline+solutions%22">Hypertonic saline solutions</searchLink><br /><searchLink fieldCode="DE" term="%22Horses%22">Horses</searchLink><br /><searchLink fieldCode="DE" term="%22Iridocyclitis%22">Iridocyclitis</searchLink><br /><searchLink fieldCode="DE" term="%22Pathologic+neovascularization%22">Pathologic neovascularization</searchLink><br /><searchLink fieldCode="DE" term="%22Felidae%22">Felidae</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Summary: This case series describes acute corneal hydrops in three young horses. Due to similarities in the clinical appearance and progression of the disease with that which is reported in humans and cats with acute corneal hydrops, traumatic Descemet's membrane rupture was suspected to be the underlying aetiology in these equine cases. The horses presented with acute severe corneal oedema with intrastromal bullae formation and anterior bulging of the corneal contour. Focal posterior corneal changes were also seen in two of three cases. Mild anterior uveitis was also present. Other causes of corneal oedema (e.g. glaucoma) were ruled out based on presentation and clinical examination. Treatment approaches were medical and included various combinations of prophylactic topical antimicrobial therapy in case of secondary corneal ulceration, anti‐inflammatory therapy for uveitis, targeted oedema therapy with topical hypertonic saline and corneal cross‐linking, and placement of a temporary partial tarsorrhaphy for corneal tamponade. The outcome was excellent in all cases, with rapid resolution of the ocular changes. Acute corneal hydrops of presumed traumatic Descemet's membrane rupture origin should be considered in cases of young horses presenting with acute corneal oedema. However, further studies are warranted to better characterise the disease and to try to confirm the suspected aetiology. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Equine Veterinary Education is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1111/eve.13455
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      – Code: eng
        Text: English
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      – SubjectFull: Cornea
        Type: general
      – SubjectFull: Edema
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      – SubjectFull: Hypertonic saline solutions
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      – SubjectFull: Horses
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      – SubjectFull: Iridocyclitis
        Type: general
      – SubjectFull: Pathologic neovascularization
        Type: general
      – SubjectFull: Felidae
        Type: general
    Titles:
      – TitleFull: Acute corneal hydrops of presumed traumatic origin: An uncontrolled case series (three horses).
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              M: 01
              Text: Jan2022
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              Y: 2022
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