AFFORDABLE REVERSE PHASE FLUID CHROMATOGRAPHIC STRATEGY FOR THE ASSESSMENT OF FOSAMPRENAVIR IN TABLETS.

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Title: AFFORDABLE REVERSE PHASE FLUID CHROMATOGRAPHIC STRATEGY FOR THE ASSESSMENT OF FOSAMPRENAVIR IN TABLETS.
Authors: Anitha, D., Manoranjani, M.1 dr.manoranjanimedikonda@gmail.com, Parameswararao, K.2
Source: Turkish Online Journal of Qualitative Inquiry. 2021, Vol. 12 Issue 6, p5118-5122. 5p.
Subject Terms: Ammonium acetate, RF values (Chromatography), Fluids, Columns, Acetonitrile, Reverse phase liquid chromatography, Liquid chromatography-mass spectrometry
Abstract: A straightforward, exact, fast and affordable reverse phase fluid chromatographic strategy has been produced for the assessment of fosamprenavir in mass and in tablets, utilizing versatile stage containing 20mM Ammonium acetate buffer (pH-3.0) and acetonitrile [50:50 %v/v] at a stream pace of 1.0ml/min. An Phenomenex Luna C18 (250 x 4.6mm i.d, 5µ) column was utilized as a stationary phase. Quantitation was performed utilizing diode exhibit identifier at 225nm and the run time noticed was 4.0min. The retention time of the medication was discovered to be 1.598min. The linearity was seen in the scope of 5.0-15μg/ml with connection coefficient 0.9974. The rate measure of fosamprenavir was 99.5 to 101.2%.The created technique was approved to decide its exactness and accuracy via completing recuperation considers and intra-day and between day examines. Consequently, the current strategy is basic, exact, precise and fast for the assessment of fosamprenavir in tablet measurement structure. [ABSTRACT FROM AUTHOR]
Copyright of Turkish Online Journal of Qualitative Inquiry is the property of Turkish Online Journal of Qualitative Inquiry and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Education Research Complete
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  Data: AFFORDABLE REVERSE PHASE FLUID CHROMATOGRAPHIC STRATEGY FOR THE ASSESSMENT OF FOSAMPRENAVIR IN TABLETS.
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  Data: <searchLink fieldCode="AR" term="%22Anitha%2C+D%2E%22">Anitha, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Manoranjani%2C+M%2E%22">Manoranjani, M.</searchLink><relatesTo>1</relatesTo><i> dr.manoranjanimedikonda@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Parameswararao%2C+K%2E%22">Parameswararao, K.</searchLink><relatesTo>2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Turkish+Online+Journal+of+Qualitative+Inquiry%22">Turkish Online Journal of Qualitative Inquiry</searchLink>. 2021, Vol. 12 Issue 6, p5118-5122. 5p.
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  Data: <searchLink fieldCode="DE" term="%22Ammonium+acetate%22">Ammonium acetate</searchLink><br /><searchLink fieldCode="DE" term="%22RF+values+%28Chromatography%29%22">RF values (Chromatography)</searchLink><br /><searchLink fieldCode="DE" term="%22Fluids%22">Fluids</searchLink><br /><searchLink fieldCode="DE" term="%22Columns%22">Columns</searchLink><br /><searchLink fieldCode="DE" term="%22Acetonitrile%22">Acetonitrile</searchLink><br /><searchLink fieldCode="DE" term="%22Reverse+phase+liquid+chromatography%22">Reverse phase liquid chromatography</searchLink><br /><searchLink fieldCode="DE" term="%22Liquid+chromatography-mass+spectrometry%22">Liquid chromatography-mass spectrometry</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: A straightforward, exact, fast and affordable reverse phase fluid chromatographic strategy has been produced for the assessment of fosamprenavir in mass and in tablets, utilizing versatile stage containing 20mM Ammonium acetate buffer (pH-3.0) and acetonitrile [50:50 %v/v] at a stream pace of 1.0ml/min. An Phenomenex Luna C18 (250 x 4.6mm i.d, 5µ) column was utilized as a stationary phase. Quantitation was performed utilizing diode exhibit identifier at 225nm and the run time noticed was 4.0min. The retention time of the medication was discovered to be 1.598min. The linearity was seen in the scope of 5.0-15μg/ml with connection coefficient 0.9974. The rate measure of fosamprenavir was 99.5 to 101.2%.The created technique was approved to decide its exactness and accuracy via completing recuperation considers and intra-day and between day examines. Consequently, the current strategy is basic, exact, precise and fast for the assessment of fosamprenavir in tablet measurement structure. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Turkish Online Journal of Qualitative Inquiry is the property of Turkish Online Journal of Qualitative Inquiry and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Code: eng
        Text: English
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        StartPage: 5118
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      – SubjectFull: Ammonium acetate
        Type: general
      – SubjectFull: RF values (Chromatography)
        Type: general
      – SubjectFull: Fluids
        Type: general
      – SubjectFull: Columns
        Type: general
      – SubjectFull: Acetonitrile
        Type: general
      – SubjectFull: Reverse phase liquid chromatography
        Type: general
      – SubjectFull: Liquid chromatography-mass spectrometry
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      – TitleFull: AFFORDABLE REVERSE PHASE FLUID CHROMATOGRAPHIC STRATEGY FOR THE ASSESSMENT OF FOSAMPRENAVIR IN TABLETS.
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              M: 07
              Text: 2021
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              Y: 2021
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