Neuromodulation of the Right Motor Cortex of the Lips With Repetitive Transcranial Magnetic Stimulation to Reduce Phonological Impairment and Improve Naming in Three Persons With Aphasia: A Single-Case Experimental Design.
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| Title: | Neuromodulation of the Right Motor Cortex of the Lips With Repetitive Transcranial Magnetic Stimulation to Reduce Phonological Impairment and Improve Naming in Three Persons With Aphasia: A Single-Case Experimental Design. |
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| Authors: | Arheix-Parras, Sophie1,2 sophie.arheix-parras@u-bordeaux.fr, Franco, Julie3, Siklafidou, Ioanna-Prodromia4, Villain, Marie5,6,7, Rogue, Caroline4, Python, Grégoire3,8, Glize, Bertrand1,2,4 |
| Source: | American Journal of Speech-Language Pathology. Jul2024, Vol. 33 Issue 4, p2023-2040. 18p. |
| Subject Terms: | *Articulation disorders, *Language & languages, *Phonological awareness, *Aphasia, *Experimental design, *Comparative studies, *Speech therapy, *Behavior therapy, Task performance, Questionnaires, Treatment effectiveness, Magnetic resonance imaging, Descriptive statistics, Linguistics, Frontal lobe, Stroke rehabilitation, Stroke, Phonetics, Data analysis software, Lips, Transcranial magnetic stimulation, Electrophysiology, Disease complications |
| Geographic Terms: | United States |
| Abstract: | Purpose: Repetitive transcranial magnetic stimulation (rTMS) can enhance aphasia recovery. Most studies have used inhibitory stimulation targeting the right inferior frontal gyrus. However, the motor cortex, observed to contribute to the prediction of aphasia recovery, is involved in word production and could be an appropriate target for rTMS. We aimed to observe behavioral changes in a picture naming task induced by inhibitory rTMS targeting the right motor cortex of the lips in people with poststroke aphasia. Method: Using a single-case experimental design, we included three participants with chronic poststroke aphasia who had phonological deficits. Each participant performed a verbal picture naming task 3 times a week for 2, 3, or 4 weeks (pseudorandom across participants) to establish a baseline naming ability for each participant. These were not therapy sessions, and no feedback was provided. Then, each participant received the intervention, inhibitory continuous theta burst stimulation targeting the right motor cortex of the lips, 3 times a week for 2 weeks. Naming testing continued 3 times a week, for these latter 2 weeks. No therapy was performed at any time during the study. Results: Visual analysis of the graphs showed a positive effect of rTMS for P2 and P3 on picture naming accuracy and a tendency toward improvement for P1. Statistical analysis showed an improvement after rTMS for P1 (τ = 0.544, p = .013, SETau = 0.288) and P2 (τ = 0.708, p = .001, SETau = 0.235). For P3, even if the intervention allowed some improvement, this was statistically nonsignificant due to a learning effect during the baseline naming testing, which lasted the longest, 4 weeks. Regarding specific language features, phonological errors significantly decreased in all patients. Conclusions: The motor cortex of the lips could be an appropriate target for rTMS to improve naming in people with poststroke aphasia suffering from a phonological deficit. This suggests the possibility to individualize the target for rTMS, according to the patient's linguistic impairment. [ABSTRACT FROM AUTHOR] |
| Copyright of American Journal of Speech-Language Pathology is the property of American Speech-Language-Hearing Association and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Education Research Complete |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: ehh DbLabel: Education Research Complete An: 178368919 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Neuromodulation of the Right Motor Cortex of the Lips With Repetitive Transcranial Magnetic Stimulation to Reduce Phonological Impairment and Improve Naming in Three Persons With Aphasia: A Single-Case Experimental Design. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Arheix-Parras%2C+Sophie%22">Arheix-Parras, Sophie</searchLink><relatesTo>1,2</relatesTo><i> sophie.arheix-parras@u-bordeaux.fr</i><br /><searchLink fieldCode="AR" term="%22Franco%2C+Julie%22">Franco, Julie</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Siklafidou%2C+Ioanna-Prodromia%22">Siklafidou, Ioanna-Prodromia</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Villain%2C+Marie%22">Villain, Marie</searchLink><relatesTo>5,6,7</relatesTo><br /><searchLink fieldCode="AR" term="%22Rogue%2C+Caroline%22">Rogue, Caroline</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Python%2C+Grégoire%22">Python, Grégoire</searchLink><relatesTo>3,8</relatesTo><br /><searchLink fieldCode="AR" term="%22Glize%2C+Bertrand%22">Glize, Bertrand</searchLink><relatesTo>1,2,4</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22American+Journal+of+Speech-Language+Pathology%22">American Journal of Speech-Language Pathology</searchLink>. Jul2024, Vol. 33 Issue 4, p2023-2040. 18p. – Name: Subject Label: Subject Terms Group: Su Data: *<searchLink fieldCode="DE" term="%22Articulation+disorders%22">Articulation disorders</searchLink><br />*<searchLink fieldCode="DE" term="%22Language+%26+languages%22">Language & languages</searchLink><br />*<searchLink fieldCode="DE" term="%22Phonological+awareness%22">Phonological awareness</searchLink><br />*<searchLink fieldCode="DE" term="%22Aphasia%22">Aphasia</searchLink><br />*<searchLink fieldCode="DE" term="%22Experimental+design%22">Experimental design</searchLink><br />*<searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br />*<searchLink fieldCode="DE" term="%22Speech+therapy%22">Speech therapy</searchLink><br />*<searchLink fieldCode="DE" term="%22Behavior+therapy%22">Behavior therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Task+performance%22">Task performance</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Linguistics%22">Linguistics</searchLink><br /><searchLink fieldCode="DE" term="%22Frontal+lobe%22">Frontal lobe</searchLink><br /><searchLink fieldCode="DE" term="%22Stroke+rehabilitation%22">Stroke rehabilitation</searchLink><br /><searchLink fieldCode="DE" term="%22Stroke%22">Stroke</searchLink><br /><searchLink fieldCode="DE" term="%22Phonetics%22">Phonetics</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Lips%22">Lips</searchLink><br /><searchLink fieldCode="DE" term="%22Transcranial+magnetic+stimulation%22">Transcranial magnetic stimulation</searchLink><br /><searchLink fieldCode="DE" term="%22Electrophysiology%22">Electrophysiology</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+complications%22">Disease complications</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22United+States%22">United States</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: Repetitive transcranial magnetic stimulation (rTMS) can enhance aphasia recovery. Most studies have used inhibitory stimulation targeting the right inferior frontal gyrus. However, the motor cortex, observed to contribute to the prediction of aphasia recovery, is involved in word production and could be an appropriate target for rTMS. We aimed to observe behavioral changes in a picture naming task induced by inhibitory rTMS targeting the right motor cortex of the lips in people with poststroke aphasia. Method: Using a single-case experimental design, we included three participants with chronic poststroke aphasia who had phonological deficits. Each participant performed a verbal picture naming task 3 times a week for 2, 3, or 4 weeks (pseudorandom across participants) to establish a baseline naming ability for each participant. These were not therapy sessions, and no feedback was provided. Then, each participant received the intervention, inhibitory continuous theta burst stimulation targeting the right motor cortex of the lips, 3 times a week for 2 weeks. Naming testing continued 3 times a week, for these latter 2 weeks. No therapy was performed at any time during the study. Results: Visual analysis of the graphs showed a positive effect of rTMS for P2 and P3 on picture naming accuracy and a tendency toward improvement for P1. Statistical analysis showed an improvement after rTMS for P1 (τ = 0.544, p = .013, SETau = 0.288) and P2 (τ = 0.708, p = .001, SETau = 0.235). For P3, even if the intervention allowed some improvement, this was statistically nonsignificant due to a learning effect during the baseline naming testing, which lasted the longest, 4 weeks. Regarding specific language features, phonological errors significantly decreased in all patients. Conclusions: The motor cortex of the lips could be an appropriate target for rTMS to improve naming in people with poststroke aphasia suffering from a phonological deficit. This suggests the possibility to individualize the target for rTMS, according to the patient's linguistic impairment. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of American Journal of Speech-Language Pathology is the property of American Speech-Language-Hearing Association and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1044/2024_AJSLP-23-00215 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 18 StartPage: 2023 Subjects: – SubjectFull: Articulation disorders Type: general – SubjectFull: Language & languages Type: general – SubjectFull: Phonological awareness Type: general – SubjectFull: Aphasia Type: general – SubjectFull: Experimental design Type: general – SubjectFull: Comparative studies Type: general – SubjectFull: Speech therapy Type: general – SubjectFull: Behavior therapy Type: general – SubjectFull: Task performance Type: general – SubjectFull: Questionnaires Type: general – SubjectFull: Treatment effectiveness Type: general – SubjectFull: Magnetic resonance imaging Type: general – SubjectFull: Descriptive statistics Type: general – SubjectFull: Linguistics Type: general – SubjectFull: Frontal lobe Type: general – SubjectFull: Stroke rehabilitation Type: general – SubjectFull: Stroke Type: general – SubjectFull: Phonetics Type: general – SubjectFull: Data analysis software Type: general – SubjectFull: Lips Type: general – SubjectFull: Transcranial magnetic stimulation Type: general – SubjectFull: Electrophysiology Type: general – SubjectFull: Disease complications Type: general – SubjectFull: United States Type: general Titles: – TitleFull: Neuromodulation of the Right Motor Cortex of the Lips With Repetitive Transcranial Magnetic Stimulation to Reduce Phonological Impairment and Improve Naming in Three Persons With Aphasia: A Single-Case Experimental Design. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Arheix-Parras, Sophie – PersonEntity: Name: NameFull: Franco, Julie – PersonEntity: Name: NameFull: Siklafidou, Ioanna-Prodromia – PersonEntity: Name: NameFull: Villain, Marie – PersonEntity: Name: NameFull: Rogue, Caroline – PersonEntity: Name: NameFull: Python, Grégoire – PersonEntity: Name: NameFull: Glize, Bertrand IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: Jul2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 10580360 Numbering: – Type: volume Value: 33 – Type: issue Value: 4 Titles: – TitleFull: American Journal of Speech-Language Pathology Type: main |
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