Leisure Physical Activity, Sedentary Behavior, and Cardiovascular Health 2–7 yr after Pregnancy in the nuMoM2b Heart Health Study Cohort.

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Title: Leisure Physical Activity, Sedentary Behavior, and Cardiovascular Health 2–7 yr after Pregnancy in the nuMoM2b Heart Health Study Cohort.
Authors: BARONE GIBBS, BETHANY1 bethany.gibbs@hsc.wvu.edu, MODLIN, SARAH1 sarah.modlin@hsc.wvu.edu, BAIREY MERZ, NOEL2 noel.baireymerz@cshs.org, HAAS, DAVID M.3 dahaas@iu.edu, KHAN, SADIYA S.4 s-khan-1@northwestern.edu, LANE, ABBI5 abbilane@umich.edu, MCNEIL, REBECCA B.6 rmcneil@rti.org, VARAGIC, JASMINA7 jasmina.varagic@nih.gov, HUBER, KIMBERLY8 kah31@pitt.edu, VASQUEZ-HUOT, LIGIA3 ligmvasq@iu.edu, CATOV, JANET M.8 catovjm@mwri.magee.edu
Source: Medicine & Science in Sports & Exercise. Jun2025, Vol. 57 Issue 6, p1229-1238. 10p.
Subject Terms: *Leisure, *Longitudinal method, Blood sugar analysis, Research funding, Sedentary lifestyles, Gestational diabetes, Lipids, Pregnant women, Pregnancy outcomes, Hypertension in pregnancy, First trimester of pregnancy, Pregnancy complications, Blood pressure, Physical activity, Regression analysis, Pregnancy
Geographic Terms: United States
Abstract: Purpose: This study aimed to evaluate whether higher moderate- to vigorous-intensity physical activity (MVPA) and lower sedentary behavior (SB) are related to better cardiovascular health (CVH) after pregnancy. Methods: In the nuMoM2b Heart Health Study cohort, Life's Essential 8 health factors (body mass index [BMI], blood pressure, glucose, and lipids) were assessed in the first trimester of pregnancy and 2–7 yr later (n = 3985). The four health factors were scored with Life's Essential 8 criteria (0 = poorest; 100 = ideal) and averaged to calculate a CVH health factor score (CVHhf). Self-reported leisure MVPA and SB were assessed at follow-up. Linear regression evaluated associations of MVPA levels and SB quartiles with follow-up CVHhf after adjustment for first trimester CVHhf and covariates. Analyses were repeated after stratification by history of hypertensive disorders of pregnancy (HDP) or gestational diabetes (GDM). Results: Over follow-up (mean 3.2 yr after delivery), CVHhf declined from 85.6 to 81.6 points (−4.0 points, P < 0.001). The decline was greatest in lipid (−8.4 points, P < 0.001) and BMI scores (−5.6 points, P < 0.001). Healthier activity profiles (higher MVPA level and lower SB quartile) were each associated with higher CVHhf at follow-up: 0.7 points higher per level of MVPA, P < 0.001; 0.5 points lower per quartile of SB, P = 0.0042. Higher MVPA level associated with healthier BMI, glucose, and lipid scores; lower SB quartile associated with healthier BMI and blood pressure scores (P < 0.05). Although HDP/GDM history was associated with lower CVHhf, patterns of CVHhf across healthier leisure MVPA levels and SB quartiles were similar in those with and without HDP or GDM. Conclusions: Higher MVPA and lower SB during leisure could help to maintain CVH health factors in the years after pregnancy, including among those who experienced HDP or GDM. [ABSTRACT FROM AUTHOR]
Copyright of Medicine & Science in Sports & Exercise is the property of Lippincott Williams & Wilkins and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Leisure Physical Activity, Sedentary Behavior, and Cardiovascular Health 2–7 yr after Pregnancy in the nuMoM2b Heart Health Study Cohort.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22BARONE+GIBBS%2C+BETHANY%22&quot;&gt;BARONE GIBBS, BETHANY&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt; bethany.gibbs@hsc.wvu.edu&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22MODLIN%2C+SARAH%22&quot;&gt;MODLIN, SARAH&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt; sarah.modlin@hsc.wvu.edu&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22BAIREY+MERZ%2C+NOEL%22&quot;&gt;BAIREY MERZ, NOEL&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;i&gt; noel.baireymerz@cshs.org&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22HAAS%2C+DAVID+M%2E%22&quot;&gt;HAAS, DAVID M.&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;i&gt; dahaas@iu.edu&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22KHAN%2C+SADIYA+S%2E%22&quot;&gt;KHAN, SADIYA S.&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt;&lt;i&gt; s-khan-1@northwestern.edu&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22LANE%2C+ABBI%22&quot;&gt;LANE, ABBI&lt;/searchLink&gt;&lt;relatesTo&gt;5&lt;/relatesTo&gt;&lt;i&gt; abbilane@umich.edu&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22MCNEIL%2C+REBECCA+B%2E%22&quot;&gt;MCNEIL, REBECCA B.&lt;/searchLink&gt;&lt;relatesTo&gt;6&lt;/relatesTo&gt;&lt;i&gt; rmcneil@rti.org&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22VARAGIC%2C+JASMINA%22&quot;&gt;VARAGIC, JASMINA&lt;/searchLink&gt;&lt;relatesTo&gt;7&lt;/relatesTo&gt;&lt;i&gt; jasmina.varagic@nih.gov&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22HUBER%2C+KIMBERLY%22&quot;&gt;HUBER, KIMBERLY&lt;/searchLink&gt;&lt;relatesTo&gt;8&lt;/relatesTo&gt;&lt;i&gt; kah31@pitt.edu&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22VASQUEZ-HUOT%2C+LIGIA%22&quot;&gt;VASQUEZ-HUOT, LIGIA&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;i&gt; ligmvasq@iu.edu&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22CATOV%2C+JANET+M%2E%22&quot;&gt;CATOV, JANET M.&lt;/searchLink&gt;&lt;relatesTo&gt;8&lt;/relatesTo&gt;&lt;i&gt; catovjm@mwri.magee.edu&lt;/i&gt;
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– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: This study aimed to evaluate whether higher moderate- to vigorous-intensity physical activity (MVPA) and lower sedentary behavior (SB) are related to better cardiovascular health (CVH) after pregnancy. Methods: In the nuMoM2b Heart Health Study cohort, Life&#39;s Essential 8 health factors (body mass index [BMI], blood pressure, glucose, and lipids) were assessed in the first trimester of pregnancy and 2–7 yr later (n = 3985). The four health factors were scored with Life&#39;s Essential 8 criteria (0 = poorest; 100 = ideal) and averaged to calculate a CVH health factor score (CVHhf). Self-reported leisure MVPA and SB were assessed at follow-up. Linear regression evaluated associations of MVPA levels and SB quartiles with follow-up CVHhf after adjustment for first trimester CVHhf and covariates. Analyses were repeated after stratification by history of hypertensive disorders of pregnancy (HDP) or gestational diabetes (GDM). Results: Over follow-up (mean 3.2 yr after delivery), CVHhf declined from 85.6 to 81.6 points (−4.0 points, P &lt; 0.001). The decline was greatest in lipid (−8.4 points, P &lt; 0.001) and BMI scores (−5.6 points, P &lt; 0.001). Healthier activity profiles (higher MVPA level and lower SB quartile) were each associated with higher CVHhf at follow-up: 0.7 points higher per level of MVPA, P &lt; 0.001; 0.5 points lower per quartile of SB, P = 0.0042. Higher MVPA level associated with healthier BMI, glucose, and lipid scores; lower SB quartile associated with healthier BMI and blood pressure scores (P &lt; 0.05). Although HDP/GDM history was associated with lower CVHhf, patterns of CVHhf across healthier leisure MVPA levels and SB quartiles were similar in those with and without HDP or GDM. Conclusions: Higher MVPA and lower SB during leisure could help to maintain CVH health factors in the years after pregnancy, including among those who experienced HDP or GDM. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: &lt;i&gt;Copyright of Medicine &amp; Science in Sports &amp; Exercise is the property of Lippincott Williams &amp; Wilkins and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1249/MSS.0000000000003660
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        Text: English
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      – SubjectFull: Leisure
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Blood sugar analysis
        Type: general
      – SubjectFull: Research funding
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      – SubjectFull: Sedentary lifestyles
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      – SubjectFull: Gestational diabetes
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      – SubjectFull: Lipids
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      – SubjectFull: Pregnant women
        Type: general
      – SubjectFull: Pregnancy outcomes
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      – SubjectFull: Hypertension in pregnancy
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      – SubjectFull: First trimester of pregnancy
        Type: general
      – SubjectFull: Pregnancy complications
        Type: general
      – SubjectFull: Blood pressure
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      – SubjectFull: Physical activity
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      – SubjectFull: Regression analysis
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      – SubjectFull: Pregnancy
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      – SubjectFull: United States
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              Text: Jun2025
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