The Impact of Adverse Childhood Experiences on the Development of Adolescent Risk-Taking: The Mediating Effect of Self-Control and Moderating Effect of Genetic Variations.

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Title: The Impact of Adverse Childhood Experiences on the Development of Adolescent Risk-Taking: The Mediating Effect of Self-Control and Moderating Effect of Genetic Variations.
Authors: Wang, Lin-Xin1,2, Li, Jian-Bin3, Liu, Zi-Hao4, Zeng, Jin5, Dou, Kai1 psydk@gzhu.edu.cn
Source: Journal of Youth & Adolescence. Jun2025, Vol. 54 Issue 6, p1356-1376. 21p.
Subject Terms: *Adolescent development, *High schools, *Psychology of high school students, *Adverse childhood experiences, Saliva analysis, Risk-taking behavior, Research funding, Questionnaires, Sex distribution, Self-control, Descriptive statistics, Genetic variation, Latent structure analysis, Statistics, Data analysis software, Confidence intervals, Genotypes
Geographic Terms: China
Abstract: Risk-taking is a concerning yet prevalent issue during adolescence and can be life-threatening. Examining its etiological sources and evolving pathways helps inform strategies to mitigate adolescents' risk-taking behavior. Studies have found that unfavorable environmental factors, such as adverse childhood experiences (ACEs), are associated with momentary levels of risk-taking in adolescents, but little is known about whether ACEs shape the developmental trajectory of risk-taking. Even less research has investigated the underlying mechanisms. Drawing on the self-regulation theory, this study examined the associations between ACEs and the developmental trajectory of adolescent risk-taking. Moreover, it also explored self-control as a mediator and genetic variations as a moderator from a "gene × environment" approach. Participants were 564 Chinese adolescents (48.40% males, Mage = 14.20 years, SD = 1.52). Adolescents reported their ACEs and self-control at T1 and risk-taking three times, with a six-month interval between each time point. Adolescents' saliva was collected at T1 for genetic extraction, and polygenetic index was created based on the gene-by-environment interaction between SNPs and ACEs for self-control via the leave-one-out machine learning approach. Findings of latent growth modeling revealed that adolescents' risk-taking decreased over time. ACEs were directly and indirectly through self-control associated with high initial levels of, and a rapid decrease in, risk-taking, especially for those with a higher polygenetic index compared to those with a lower polygenetic index. Theoretically, these results suggest a tripartite model of adolescent risk-taking, such that risk-taking is the combined function of adverse experiences in early years, low self-control, and carriage of sensitive genes. Practically, intervention strategies should reduce childhood adversities, build up self-control, and consider the potential impacts of genetic plasticity. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Youth & Adolescence is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: The Impact of Adverse Childhood Experiences on the Development of Adolescent Risk-Taking: The Mediating Effect of Self-Control and Moderating Effect of Genetic Variations.
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  Data: <searchLink fieldCode="AR" term="%22Wang%2C+Lin-Xin%22">Wang, Lin-Xin</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Li%2C+Jian-Bin%22">Li, Jian-Bin</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Liu%2C+Zi-Hao%22">Liu, Zi-Hao</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Zeng%2C+Jin%22">Zeng, Jin</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Dou%2C+Kai%22">Dou, Kai</searchLink><relatesTo>1</relatesTo><i> psydk@gzhu.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Youth+%26+Adolescence%22">Journal of Youth & Adolescence</searchLink>. Jun2025, Vol. 54 Issue 6, p1356-1376. 21p.
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  Data: Risk-taking is a concerning yet prevalent issue during adolescence and can be life-threatening. Examining its etiological sources and evolving pathways helps inform strategies to mitigate adolescents' risk-taking behavior. Studies have found that unfavorable environmental factors, such as adverse childhood experiences (ACEs), are associated with momentary levels of risk-taking in adolescents, but little is known about whether ACEs shape the developmental trajectory of risk-taking. Even less research has investigated the underlying mechanisms. Drawing on the self-regulation theory, this study examined the associations between ACEs and the developmental trajectory of adolescent risk-taking. Moreover, it also explored self-control as a mediator and genetic variations as a moderator from a "gene × environment" approach. Participants were 564 Chinese adolescents (48.40% males, Mage = 14.20 years, SD = 1.52). Adolescents reported their ACEs and self-control at T1 and risk-taking three times, with a six-month interval between each time point. Adolescents' saliva was collected at T1 for genetic extraction, and polygenetic index was created based on the gene-by-environment interaction between SNPs and ACEs for self-control via the leave-one-out machine learning approach. Findings of latent growth modeling revealed that adolescents' risk-taking decreased over time. ACEs were directly and indirectly through self-control associated with high initial levels of, and a rapid decrease in, risk-taking, especially for those with a higher polygenetic index compared to those with a lower polygenetic index. Theoretically, these results suggest a tripartite model of adolescent risk-taking, such that risk-taking is the combined function of adverse experiences in early years, low self-control, and carriage of sensitive genes. Practically, intervention strategies should reduce childhood adversities, build up self-control, and consider the potential impacts of genetic plasticity. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Journal of Youth & Adolescence is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1007/s10964-025-02136-5
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 21
        StartPage: 1356
    Subjects:
      – SubjectFull: Adolescent development
        Type: general
      – SubjectFull: High schools
        Type: general
      – SubjectFull: Psychology of high school students
        Type: general
      – SubjectFull: Adverse childhood experiences
        Type: general
      – SubjectFull: Saliva analysis
        Type: general
      – SubjectFull: Risk-taking behavior
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Sex distribution
        Type: general
      – SubjectFull: Self-control
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Genetic variation
        Type: general
      – SubjectFull: Latent structure analysis
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      – SubjectFull: Statistics
        Type: general
      – SubjectFull: Data analysis software
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      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Genotypes
        Type: general
      – SubjectFull: China
        Type: general
    Titles:
      – TitleFull: The Impact of Adverse Childhood Experiences on the Development of Adolescent Risk-Taking: The Mediating Effect of Self-Control and Moderating Effect of Genetic Variations.
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              M: 06
              Text: Jun2025
              Type: published
              Y: 2025
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