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Analysis of the Sensitivity to Changes in the Inventory of Depression and Anxiety Symptoms–II (IDAS-II) Scores and Minimal Clinically Important Differences Regarding Quality of Life and Disability in Patients.

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Title: Analysis of the Sensitivity to Changes in the Inventory of Depression and Anxiety Symptoms–II (IDAS-II) Scores and Minimal Clinically Important Differences Regarding Quality of Life and Disability in Patients.
Authors: Sanchez-Garcia, Manuel1,2, Lozano-Rojas, Oscar1,2, Díaz-Batanero, Carmen1,2, De la Rosa-Cáceres, Ana1,3 anamaria.delarosacaceres@unir.net
Source: Psychological Assessment. Sep2025, Vol. 37 Issue 9, p401-414. 14p.
Subject Terms: *Data analysis, *Anxiety, *Internalizing behavior, *Quality of life, *Psychological tests, *Mental depression, Anxiety treatment, Research funding, Functional assessment, Research evaluation, Questionnaires, Health surveys, Decision making in clinical medicine, Statistics
Abstract: The Inventory of Depression and Anxiety Symptoms–II (IDAS-II) addresses current clinical demands by providing individual scores for depressive, anxiety, and bipolar symptoms consistent with transdiagnostic approaches and the Hierarchical Taxonomy of Psychopathology. The general aim was to expand the clinical utility of the IDAS-II to assess changes in internalizing symptoms, quality of life (QoL), and disability. Participants included 1,072 community adults (50% women) and 289 patients (74% women) who completed the IDAS-II. Patients also completed the Short Form–36 Health Survey and World Health Organization Disability Assessment Schedule to evaluate QoL and disability, respectively. First, the sensitivity of the IDAS-II scores to treatment impact was assessed through statistical significance and reliable changes based on the internal consistency of the IDAS-II. Second, the relationship between changes in IDAS-II scores and changes in QoL and disability was analyzed using weighted Cohen's κ and Spearman correlations. Third, an anchor-based longitudinal method determined the minimal clinically important difference in QoL and disability for the IDAS-II scales (i.e., the smallest difference in IDAS-II scores perceived as beneficial for QoL and disability). Reliable change index values and cutoff c were provided to identify reliable improvement, deterioration, no change, and clinically significant change for each symptom. Changes in general depression and dysphoria were most strongly associated with changes in QoL and disability. The minimal clinically important difference values for the IDAS-II provide insights into perceived QoL and disability improvement without requiring additional measures. Tracking symptom changes and their implications for QoL and disability is useful in guiding evidence-based decisions in clinical practice. Public Significance Statement: This study expands the clinical utility of the Inventory of Depression and Anxiety Symptoms–II, an instrument that allows clinicians to assess the symptoms of depression, anxiety, and bipolar disorder in detail. Specifically, it provides cutoff points that help clinicians decide when to initiate, change, or terminate treatment based on changes in the severity of symptoms and considering the impact of these changes on quality of life and disability. [ABSTRACT FROM AUTHOR]
Copyright of Psychological Assessment is the property of American Psychological Association and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Education Research Complete
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  Data: Analysis of the Sensitivity to Changes in the Inventory of Depression and Anxiety Symptoms–II (IDAS-II) Scores and Minimal Clinically Important Differences Regarding Quality of Life and Disability in Patients.
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  Data: <searchLink fieldCode="JN" term="%22Psychological+Assessment%22">Psychological Assessment</searchLink>. Sep2025, Vol. 37 Issue 9, p401-414. 14p.
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  Data: The Inventory of Depression and Anxiety Symptoms–II (IDAS-II) addresses current clinical demands by providing individual scores for depressive, anxiety, and bipolar symptoms consistent with transdiagnostic approaches and the Hierarchical Taxonomy of Psychopathology. The general aim was to expand the clinical utility of the IDAS-II to assess changes in internalizing symptoms, quality of life (QoL), and disability. Participants included 1,072 community adults (50% women) and 289 patients (74% women) who completed the IDAS-II. Patients also completed the Short Form–36 Health Survey and World Health Organization Disability Assessment Schedule to evaluate QoL and disability, respectively. First, the sensitivity of the IDAS-II scores to treatment impact was assessed through statistical significance and reliable changes based on the internal consistency of the IDAS-II. Second, the relationship between changes in IDAS-II scores and changes in QoL and disability was analyzed using weighted Cohen's κ and Spearman correlations. Third, an anchor-based longitudinal method determined the minimal clinically important difference in QoL and disability for the IDAS-II scales (i.e., the smallest difference in IDAS-II scores perceived as beneficial for QoL and disability). Reliable change index values and cutoff c were provided to identify reliable improvement, deterioration, no change, and clinically significant change for each symptom. Changes in general depression and dysphoria were most strongly associated with changes in QoL and disability. The minimal clinically important difference values for the IDAS-II provide insights into perceived QoL and disability improvement without requiring additional measures. Tracking symptom changes and their implications for QoL and disability is useful in guiding evidence-based decisions in clinical practice. Public Significance Statement: This study expands the clinical utility of the Inventory of Depression and Anxiety Symptoms–II, an instrument that allows clinicians to assess the symptoms of depression, anxiety, and bipolar disorder in detail. Specifically, it provides cutoff points that help clinicians decide when to initiate, change, or terminate treatment based on changes in the severity of symptoms and considering the impact of these changes on quality of life and disability. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Psychological Assessment is the property of American Psychological Association and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1037/pas0001389
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      – Code: eng
        Text: English
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        PageCount: 14
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      – SubjectFull: Data analysis
        Type: general
      – SubjectFull: Anxiety
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      – SubjectFull: Internalizing behavior
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      – SubjectFull: Psychological tests
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      – SubjectFull: Mental depression
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      – SubjectFull: Anxiety treatment
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      – SubjectFull: Decision making in clinical medicine
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      – SubjectFull: Statistics
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      – TitleFull: Analysis of the Sensitivity to Changes in the Inventory of Depression and Anxiety Symptoms–II (IDAS-II) Scores and Minimal Clinically Important Differences Regarding Quality of Life and Disability in Patients.
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              Text: Sep2025
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