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Prevalence of Labor Induction, its Indication, and Feto-Maternal Outcomes in Ethiopia: A Systematic Review and Meta-Analysis.

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Title: Prevalence of Labor Induction, its Indication, and Feto-Maternal Outcomes in Ethiopia: A Systematic Review and Meta-Analysis.
Authors: Figa, Zerihun1 (AUTHOR) zerihunfiga2022@gmail.com, Getnet Zemeskel, Addisu1 (AUTHOR), Alemu, Asrat1 (AUTHOR), Gashaw, Anteneh1 (AUTHOR), Gossaye Ejigu, Aschalew1 (AUTHOR), Tilahun, Nigatu1 (AUTHOR), Temesgen, Tesfaye1 (AUTHOR), Bedecha, Fikru1 (AUTHOR), Tesfaye Gebre, Bereket1 (AUTHOR)
Source: Inquiry (00469580). 1/8/2026, Vol. 63, p1-9. 9p.
Subject Terms: Prolonged pregnancy, Cesarean section, Wounds & injuries, Vagina, Research funding, Fetal growth retardation, Hypertension, Pregnancy outcomes, Meta-analysis, Descriptive statistics, Perinatal death, Postpartum hemorrhage, Induced labor (Obstetrics), Systematic reviews, MEDLINE, Medical databases, Online information services, Confidence intervals, Pregnancy complications, Amniotic liquid
Geographic Terms: Ethiopia
Abstract: Labor induction (IOL) is a common obstetric intervention to stimulate uterine contractions before the spontaneous onset of labor, with the goal of achieving vaginal delivery. It is indicated for various reasons, including post-term pregnancy, premature rupture of membranes (PROM), maternal medical conditions, and fetal growth restriction. This study aims to evaluate the prevalence of labor induction, its indications, and the associated maternal and fetal outcomes in Ethiopia. A comprehensive search for relevant articles was conducted using widely recognized databases such as Google Scholar, Cochrane, PubMed, HINARI, Web of Science, African Online, and institutional repositories from Ethiopian universities. Data were extracted using the standard format provided by the Joanna Briggs Institute. The Cochran Q test and I 2 statistics were employed to assess the heterogeneity of the studies. Publication bias was evaluated using a Funnel plot and Egger's test. A Forest plot was used to present the pooled prevalence of labor induction in Ethiopia. This systematic review and meta-analysis revealed that the overall pooled prevalence of induction of labor in Ethiopia was 14.4% (95% CI: 11.09-17.70; I 2 = 95.7%, P <.01). The primary indications for labor induction included premature rupture of membranes (33.91%), intrauterine fetal death (8.8%), intrauterine growth restriction (4.85%), post-term pregnancy (21.49%), oligohydramnios (12.2%), and hypertensive disorders (30.7%). Maternal complications related to induction of labor included postpartum hemorrhage (9.47%), cesarean section (28.68%), instrumental delivery (18.82%), and vaginal tears (14.45%). Adverse fetal outcomes included low Apgar scores at 1 min, fetal death, and neonatal intensive care unit (NICU) admission, with respective rates of 48.2%, 6.11%, and 15.5%. According to this systematic review and meta-analysis, the estimated overall prevalence of induction of labor in Ethiopia is 14.4%. The indications for induction of labor include premature rupture of membranes (PROM), intrauterine fetal death (IUFD), intrauterine growth restriction (IUGR), post-term pregnancy, oligohydramnios, and hypertensive disorders. Maternal complications of labor induction include postpartum hemorrhage (PPH), cesarean section, instrumental delivery, and vaginal tear. Adverse fetal outcomes associated with induction of labor include a low first-minute Apgar score, fetal death, and admission to the neonatal intensive care unit (NICU). Careful consideration and balancing of risks are essential when deciding to induce labor. Additionally, clear national protocols and follow-up on induction of labor are crucial to mitigate these risks. Registration number: reviewregistry2051. [ABSTRACT FROM AUTHOR]
Copyright of Inquiry (00469580) is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Prevalence of Labor Induction, its Indication, and Feto-Maternal Outcomes in Ethiopia: A Systematic Review and Meta-Analysis.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Ethiopia%22&quot;&gt;Ethiopia&lt;/searchLink&gt;
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  Data: Labor induction (IOL) is a common obstetric intervention to stimulate uterine contractions before the spontaneous onset of labor, with the goal of achieving vaginal delivery. It is indicated for various reasons, including post-term pregnancy, premature rupture of membranes (PROM), maternal medical conditions, and fetal growth restriction. This study aims to evaluate the prevalence of labor induction, its indications, and the associated maternal and fetal outcomes in Ethiopia. A comprehensive search for relevant articles was conducted using widely recognized databases such as Google Scholar, Cochrane, PubMed, HINARI, Web of Science, African Online, and institutional repositories from Ethiopian universities. Data were extracted using the standard format provided by the Joanna Briggs Institute. The Cochran Q test and I 2 statistics were employed to assess the heterogeneity of the studies. Publication bias was evaluated using a Funnel plot and Egger&#39;s test. A Forest plot was used to present the pooled prevalence of labor induction in Ethiopia. This systematic review and meta-analysis revealed that the overall pooled prevalence of induction of labor in Ethiopia was 14.4% (95% CI: 11.09-17.70; I 2 = 95.7%, P &lt;.01). The primary indications for labor induction included premature rupture of membranes (33.91%), intrauterine fetal death (8.8%), intrauterine growth restriction (4.85%), post-term pregnancy (21.49%), oligohydramnios (12.2%), and hypertensive disorders (30.7%). Maternal complications related to induction of labor included postpartum hemorrhage (9.47%), cesarean section (28.68%), instrumental delivery (18.82%), and vaginal tears (14.45%). Adverse fetal outcomes included low Apgar scores at 1 min, fetal death, and neonatal intensive care unit (NICU) admission, with respective rates of 48.2%, 6.11%, and 15.5%. According to this systematic review and meta-analysis, the estimated overall prevalence of induction of labor in Ethiopia is 14.4%. The indications for induction of labor include premature rupture of membranes (PROM), intrauterine fetal death (IUFD), intrauterine growth restriction (IUGR), post-term pregnancy, oligohydramnios, and hypertensive disorders. Maternal complications of labor induction include postpartum hemorrhage (PPH), cesarean section, instrumental delivery, and vaginal tear. Adverse fetal outcomes associated with induction of labor include a low first-minute Apgar score, fetal death, and admission to the neonatal intensive care unit (NICU). Careful consideration and balancing of risks are essential when deciding to induce labor. Additionally, clear national protocols and follow-up on induction of labor are crucial to mitigate these risks. Registration number: reviewregistry2051. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Inquiry (00469580) is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1177/00469580251411644
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      – Code: eng
        Text: English
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      – SubjectFull: Prolonged pregnancy
        Type: general
      – SubjectFull: Cesarean section
        Type: general
      – SubjectFull: Wounds & injuries
        Type: general
      – SubjectFull: Vagina
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      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Fetal growth retardation
        Type: general
      – SubjectFull: Hypertension
        Type: general
      – SubjectFull: Pregnancy outcomes
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      – SubjectFull: Meta-analysis
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      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Perinatal death
        Type: general
      – SubjectFull: Postpartum hemorrhage
        Type: general
      – SubjectFull: Induced labor (Obstetrics)
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        Type: general
      – SubjectFull: Amniotic liquid
        Type: general
      – SubjectFull: Ethiopia
        Type: general
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      – TitleFull: Prevalence of Labor Induction, its Indication, and Feto-Maternal Outcomes in Ethiopia: A Systematic Review and Meta-Analysis.
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              Text: 1/8/2026
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