Cancer-Related Fatigue, Psychological Symptoms, and Sleep Quality and Influencing Factors in Cancer Patients Receiving Chemotherapy.

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Title: Cancer-Related Fatigue, Psychological Symptoms, and Sleep Quality and Influencing Factors in Cancer Patients Receiving Chemotherapy.
Authors: Said, Nizar B.1 (NURSE) nizarsaid@najah.edu, Alsayed, Aseel1 (NURSE)
Source: Inquiry (00469580). 2/21/2026, Vol. 63, p1-8. 8p.
Subject Terms: *Behavior disorders, *Self-evaluation, *Academic medical centers, *Data analysis, *Anxiety, *Economic status, *Psychological adaptation, *Psychological tests, *Comparative studies, *Mental depression, *Educational attainment, *Evaluation, Mental depression risk factors, Risk assessment, Cross-sectional method, Disease duration, Cronbach's alpha, T-test (Statistics), Psychological distress, Statistical sampling, Questionnaires, Pilot projects, Breast tumors, Sex distribution, Symptoms, Severity of illness index, Quantitative research, Descriptive statistics, Disease prevalence, Chi-squared test, Multivariate analysis, Cancer chemotherapy, Marital status, One-way analysis of variance, Statistics, Analysis of variance, Lung tumors, Cancer fatigue, Sleep quality, Cancer patient psychology, Data analysis software, Tumors, Digestive organs, Disease risk factors
Geographic Terms: Palestine
Abstract: Cancer-Related Fatigue, Psychological Symptoms (Anxiety and depression), and poor sleep quality are prevalent among patients with cancer undergoing chemotherapy. These psychological symptoms can significantly impair the overall well-being and treatment adherence of patients. To examine cancer-related fatigue, anxiety, depression, and sleep quality among patients receiving chemotherapy, and to determine how these symptoms vary according to selected demographic and clinical characteristics. A quantitative, cross-sectional study was conducted at An Najah National University Hospital. A convenience sample of 150 cancer patients receiving chemotherapy was recruited. Among 150 cancer patients receiving chemotherapy, fatigue was the most prevalent symptom (24.93 ± 13.05), with higher levels reported by males compared to females, t (147) = 2.49, P =.014, and by married patients (P <.001). Anxiety and depression affected 69.3% and 67.1% of patients, respectively, with 25.2% experiencing moderate to severe anxiety and 28.1% experiencing moderate to severe depression. 52.7% of patients reported poor sleep quality. Fatigue was strongly correlated with sleep quality (r =.644, P <.001) and moderately correlated with anxiety (r =.390, P <.01) and depression (r =.372, P <.01). Symptom severity varied significantly according to cancer stage (P <.01), type (P <.05), duration (P <.01), income, and education (P <.05). The findings underscore the critical need for comprehensive cancer care that addresses not only the physical aspects of fatigue and sleep disturbances but also the psychological impacts of anxiety and depression. [ABSTRACT FROM AUTHOR]
Copyright of Inquiry (00469580) is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Cancer-Related Fatigue, Psychological Symptoms, and Sleep Quality and Influencing Factors in Cancer Patients Receiving Chemotherapy.
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  Data: Cancer-Related Fatigue, Psychological Symptoms (Anxiety and depression), and poor sleep quality are prevalent among patients with cancer undergoing chemotherapy. These psychological symptoms can significantly impair the overall well-being and treatment adherence of patients. To examine cancer-related fatigue, anxiety, depression, and sleep quality among patients receiving chemotherapy, and to determine how these symptoms vary according to selected demographic and clinical characteristics. A quantitative, cross-sectional study was conducted at An Najah National University Hospital. A convenience sample of 150 cancer patients receiving chemotherapy was recruited. Among 150 cancer patients receiving chemotherapy, fatigue was the most prevalent symptom (24.93 &#177; 13.05), with higher levels reported by males compared to females, t (147) = 2.49, P =.014, and by married patients (P &lt;.001). Anxiety and depression affected 69.3% and 67.1% of patients, respectively, with 25.2% experiencing moderate to severe anxiety and 28.1% experiencing moderate to severe depression. 52.7% of patients reported poor sleep quality. Fatigue was strongly correlated with sleep quality (r =.644, P &lt;.001) and moderately correlated with anxiety (r =.390, P &lt;.01) and depression (r =.372, P &lt;.01). Symptom severity varied significantly according to cancer stage (P &lt;.01), type (P &lt;.05), duration (P &lt;.01), income, and education (P &lt;.05). The findings underscore the critical need for comprehensive cancer care that addresses not only the physical aspects of fatigue and sleep disturbances but also the psychological impacts of anxiety and depression. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Inquiry (00469580) is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1177/00469580261422596
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        Text: English
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        Type: general
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        Type: general
      – SubjectFull: Academic medical centers
        Type: general
      – SubjectFull: Data analysis
        Type: general
      – SubjectFull: Anxiety
        Type: general
      – SubjectFull: Economic status
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      – SubjectFull: Psychological adaptation
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      – SubjectFull: Psychological tests
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      – SubjectFull: Comparative studies
        Type: general
      – SubjectFull: Mental depression
        Type: general
      – SubjectFull: Educational attainment
        Type: general
      – SubjectFull: Evaluation
        Type: general
      – SubjectFull: Mental depression risk factors
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Disease duration
        Type: general
      – SubjectFull: Cronbach's alpha
        Type: general
      – SubjectFull: T-test (Statistics)
        Type: general
      – SubjectFull: Psychological distress
        Type: general
      – SubjectFull: Statistical sampling
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Pilot projects
        Type: general
      – SubjectFull: Breast tumors
        Type: general
      – SubjectFull: Sex distribution
        Type: general
      – SubjectFull: Symptoms
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      – SubjectFull: Multivariate analysis
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      – SubjectFull: Cancer chemotherapy
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      – SubjectFull: Marital status
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      – SubjectFull: One-way analysis of variance
        Type: general
      – SubjectFull: Statistics
        Type: general
      – SubjectFull: Analysis of variance
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      – SubjectFull: Lung tumors
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      – SubjectFull: Cancer fatigue
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      – SubjectFull: Sleep quality
        Type: general
      – SubjectFull: Cancer patient psychology
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Tumors
        Type: general
      – SubjectFull: Digestive organs
        Type: general
      – SubjectFull: Disease risk factors
        Type: general
      – SubjectFull: Palestine
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      – TitleFull: Cancer-Related Fatigue, Psychological Symptoms, and Sleep Quality and Influencing Factors in Cancer Patients Receiving Chemotherapy.
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              Text: 2/21/2026
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