Shockwave therapy for coronary calcification: the evolving role of intravascular lithotripsy in coronary interventions.

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Title: Shockwave therapy for coronary calcification: the evolving role of intravascular lithotripsy in coronary interventions.
Authors: Jóźwiak, Piotr1 piotr.jozwiak098@gmail.com, Rybak, Adam1 adam.rybak.99@gmail.com, Wysieńska, Maria2 wysienska@gmail.com, Biaduń-Mućko, Weronika1 w.biadun1@gmail.com, Rogowska-Borettini, Kinga3 kinga.rogowska0504@gmail.com, Romanowska, Aleksandra4 olarrromanowska@gmail.com, Malmur, Paweł Arkadiusz4 pmalmur1@gmail.com
Source: Journal of Education, Health & Sport. 2026, Vol. 88, p1-16. 16p.
Subject Terms: Coronary artery calcification, Percutaneous coronary intervention, Treatment effectiveness, Extracorporeal shock wave therapy, Coronary artery stenosis, Major adverse cardiovascular events
Abstract: Severely calcified coronary lesions represent a significant challenge during percutaneous coronary interventions (PCI), often limiting optimal stent deployment and increasing the risk of procedural complications. Intravascular lithotripsy (IVL) is an emerging technology designed to modify calcified plaques through the application of acoustic shockwaves, offering a safer and more controlled alternative to traditional atherectomy. Aim of the Study: This study aims to provide a comprehensive overview of the intravascular lithotripsy (IVL) technique, its mechanism of action, indications, and contraindications. Additionally, it evaluates the procedural efficacy, safety profile, and clinical outcomes of IVL based on current clinical trial data and real-world experience. Material and Methods: A narrative review was conducted, incorporating findings from major clinical trials (Disrupt CAD I–IV) and observational registries, with a focus on procedural success, complication rates, and major adverse cardiac events (MACE). The review includes comparative analysis of IVL outcomes in de novo lesions, in-stent restenosis (ISR), chronic total occlusions (CTO), and complex anatomical scenarios. Conclusions: IVL is a highly effective and safe modality for the modification of calcified coronary lesions. It consistently demonstrates procedural success rates exceeding 90%, with a low incidence of complications such as perforation or dissection. Clinical efficacy is sustained in both short- and long-term follow-up, with low MACE rates observed across studies. IVL is particularly valuable in cases resistant to conventional techniques. However, limitations related to cost, access, and certain patient populations necessitate further randomized studies to establish its role as a standard of care. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Education, Health & Sport is the property of Nicolaus Copernicus University in Torun and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Education Research Complete
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  Data: Shockwave therapy for coronary calcification: the evolving role of intravascular lithotripsy in coronary interventions.
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  Data: <searchLink fieldCode="AR" term="%22Jóźwiak%2C+Piotr%22">Jóźwiak, Piotr</searchLink><relatesTo>1</relatesTo><i> piotr.jozwiak098@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Rybak%2C+Adam%22">Rybak, Adam</searchLink><relatesTo>1</relatesTo><i> adam.rybak.99@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Wysieńska%2C+Maria%22">Wysieńska, Maria</searchLink><relatesTo>2</relatesTo><i> wysienska@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Biaduń-Mućko%2C+Weronika%22">Biaduń-Mućko, Weronika</searchLink><relatesTo>1</relatesTo><i> w.biadun1@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Rogowska-Borettini%2C+Kinga%22">Rogowska-Borettini, Kinga</searchLink><relatesTo>3</relatesTo><i> kinga.rogowska0504@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Romanowska%2C+Aleksandra%22">Romanowska, Aleksandra</searchLink><relatesTo>4</relatesTo><i> olarrromanowska@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Malmur%2C+Paweł+Arkadiusz%22">Malmur, Paweł Arkadiusz</searchLink><relatesTo>4</relatesTo><i> pmalmur1@gmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Education%2C+Health+%26+Sport%22">Journal of Education, Health & Sport</searchLink>. 2026, Vol. 88, p1-16. 16p.
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  Data: <searchLink fieldCode="DE" term="%22Coronary+artery+calcification%22">Coronary artery calcification</searchLink><br /><searchLink fieldCode="DE" term="%22Percutaneous+coronary+intervention%22">Percutaneous coronary intervention</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Extracorporeal+shock+wave+therapy%22">Extracorporeal shock wave therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Coronary+artery+stenosis%22">Coronary artery stenosis</searchLink><br /><searchLink fieldCode="DE" term="%22Major+adverse+cardiovascular+events%22">Major adverse cardiovascular events</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Severely calcified coronary lesions represent a significant challenge during percutaneous coronary interventions (PCI), often limiting optimal stent deployment and increasing the risk of procedural complications. Intravascular lithotripsy (IVL) is an emerging technology designed to modify calcified plaques through the application of acoustic shockwaves, offering a safer and more controlled alternative to traditional atherectomy. Aim of the Study: This study aims to provide a comprehensive overview of the intravascular lithotripsy (IVL) technique, its mechanism of action, indications, and contraindications. Additionally, it evaluates the procedural efficacy, safety profile, and clinical outcomes of IVL based on current clinical trial data and real-world experience. Material and Methods: A narrative review was conducted, incorporating findings from major clinical trials (Disrupt CAD I–IV) and observational registries, with a focus on procedural success, complication rates, and major adverse cardiac events (MACE). The review includes comparative analysis of IVL outcomes in de novo lesions, in-stent restenosis (ISR), chronic total occlusions (CTO), and complex anatomical scenarios. Conclusions: IVL is a highly effective and safe modality for the modification of calcified coronary lesions. It consistently demonstrates procedural success rates exceeding 90%, with a low incidence of complications such as perforation or dissection. Clinical efficacy is sustained in both short- and long-term follow-up, with low MACE rates observed across studies. IVL is particularly valuable in cases resistant to conventional techniques. However, limitations related to cost, access, and certain patient populations necessitate further randomized studies to establish its role as a standard of care. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Education, Health & Sport is the property of Nicolaus Copernicus University in Torun and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.12775/JEHS.2026.88.68121
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 16
        StartPage: 1
    Subjects:
      – SubjectFull: Coronary artery calcification
        Type: general
      – SubjectFull: Percutaneous coronary intervention
        Type: general
      – SubjectFull: Treatment effectiveness
        Type: general
      – SubjectFull: Extracorporeal shock wave therapy
        Type: general
      – SubjectFull: Coronary artery stenosis
        Type: general
      – SubjectFull: Major adverse cardiovascular events
        Type: general
    Titles:
      – TitleFull: Shockwave therapy for coronary calcification: the evolving role of intravascular lithotripsy in coronary interventions.
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            NameFull: Jóźwiak, Piotr
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            NameFull: Rybak, Adam
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            NameFull: Biaduń-Mućko, Weronika
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            NameFull: Rogowska-Borettini, Kinga
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            NameFull: Romanowska, Aleksandra
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            NameFull: Malmur, Paweł Arkadiusz
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            – D: 15
              M: 01
              Text: 2026
              Type: published
              Y: 2026
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