View in EDS HTML Full Text PDF Full Text

Association of Social Frailty With Incident Dementia and Cognitive Decline in Middle-Aged and Older Adults: A Prospective Cohort Study.

Saved in:
Bibliographic Details
Title: Association of Social Frailty With Incident Dementia and Cognitive Decline in Middle-Aged and Older Adults: A Prospective Cohort Study.
Authors: Chen, Qian1 (AUTHOR), Tang, Nian2 (AUTHOR) T1218011@cqrk.edu.cn
Source: Inquiry (00469580). 7/11/2026, Vol. 63, p1-12. 12p.
Subject Terms: *Longitudinal method, Frail elderly, Cognition disorders, Dementia, Confidence intervals, Proportional hazards models, Old age
Abstract: Introduction: Social frailty is a multidimensional construct encompassing social behaviors, social resources, and the fulfillment of basic social needs, and is increasingly recognized as an important factor influencing cognitive function. This study aimed to evaluate the association between social frailty and incident dementia as well as changes in cognitive function among middle-aged and older adults, providing novel evidence through a longitudinal cohort applying a multidimensional social frailty framework. Methods: Data were derived from the China Health and Retirement Longitudinal Study (CHARLS). Social frailty was defined across four dimensions: general resources, social behavior, social resources, and basic social needs. Cognitive function was assessed using tests of memory, orientation, and executive function. Cox proportional hazards models were used to analyze the association between social frailty and incident dementia, and linear mixed-effects models were applied to examine the relationships between social frailty and changes in overall and domain-specific cognitive function. Results: Compared with the socially robust group, the socially frail group showed an increased risk of incident dementia in Model 1 and Model 3 (HR = 2.42, 95% CI: 1.50–3.89, P < 0.001; HR = 1.52, 95% CI: 0.92–2.53, P = 0.102, respectively). Among the dimensions, only the social behavior dimension remained significantly positively associated with dementia risk (HR = 1.38, 95% CI: 1.11–1.73, P = 0.004). Regarding cognitive function changes, social frailty was significantly associated with decline in overall cognitive function (β = −0.12, 95% CI: −0.18 to −0.06, P < 0.001), primarily reflected in memory decline (β = −0.14, 95% CI: −0.21 to −0.08, P < 0.001), whereas no significant associations were observed for orientation or executive function. Conclusion: Social frailty is associated with a higher risk of incident dementia and faster cognitive decline, highlighting its potential as an early and modifiable risk marker for cognitive aging. [ABSTRACT FROM AUTHOR]
Copyright of Inquiry (00469580) is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Education Research Complete
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: ehh
DbLabel: Education Research Complete
An: 195272843
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Association of Social Frailty With Incident Dementia and Cognitive Decline in Middle-Aged and Older Adults: A Prospective Cohort Study.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Chen%2C+Qian%22&quot;&gt;Chen, Qian&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tang%2C+Nian%22&quot;&gt;Tang, Nian&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt; (AUTHOR)&lt;i&gt; T1218011@cqrk.edu.cn&lt;/i&gt;
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Inquiry+%2800469580%29%22&quot;&gt;Inquiry (00469580)&lt;/searchLink&gt;. 7/11/2026, Vol. 63, p1-12. 12p.
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: *&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Longitudinal+method%22&quot;&gt;Longitudinal method&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Frail+elderly%22&quot;&gt;Frail elderly&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cognition+disorders%22&quot;&gt;Cognition disorders&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Dementia%22&quot;&gt;Dementia&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Confidence+intervals%22&quot;&gt;Confidence intervals&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Proportional+hazards+models%22&quot;&gt;Proportional hazards models&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Old+age%22&quot;&gt;Old age&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Introduction: Social frailty is a multidimensional construct encompassing social behaviors, social resources, and the fulfillment of basic social needs, and is increasingly recognized as an important factor influencing cognitive function. This study aimed to evaluate the association between social frailty and incident dementia as well as changes in cognitive function among middle-aged and older adults, providing novel evidence through a longitudinal cohort applying a multidimensional social frailty framework. Methods: Data were derived from the China Health and Retirement Longitudinal Study (CHARLS). Social frailty was defined across four dimensions: general resources, social behavior, social resources, and basic social needs. Cognitive function was assessed using tests of memory, orientation, and executive function. Cox proportional hazards models were used to analyze the association between social frailty and incident dementia, and linear mixed-effects models were applied to examine the relationships between social frailty and changes in overall and domain-specific cognitive function. Results: Compared with the socially robust group, the socially frail group showed an increased risk of incident dementia in Model 1 and Model 3 (HR = 2.42, 95% CI: 1.50–3.89, P &lt; 0.001; HR = 1.52, 95% CI: 0.92–2.53, P = 0.102, respectively). Among the dimensions, only the social behavior dimension remained significantly positively associated with dementia risk (HR = 1.38, 95% CI: 1.11–1.73, P = 0.004). Regarding cognitive function changes, social frailty was significantly associated with decline in overall cognitive function (β = −0.12, 95% CI: −0.18 to −0.06, P &lt; 0.001), primarily reflected in memory decline (β = −0.14, 95% CI: −0.21 to −0.08, P &lt; 0.001), whereas no significant associations were observed for orientation or executive function. Conclusion: Social frailty is associated with a higher risk of incident dementia and faster cognitive decline, highlighting its potential as an early and modifiable risk marker for cognitive aging. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of Inquiry (00469580) is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=ehh&AN=195272843
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1177/00469580261468818
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 1
    Subjects:
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Frail elderly
        Type: general
      – SubjectFull: Cognition disorders
        Type: general
      – SubjectFull: Dementia
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Proportional hazards models
        Type: general
      – SubjectFull: Old age
        Type: general
    Titles:
      – TitleFull: Association of Social Frailty With Incident Dementia and Cognitive Decline in Middle-Aged and Older Adults: A Prospective Cohort Study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Chen, Qian
      – PersonEntity:
          Name:
            NameFull: Tang, Nian
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 11
              M: 07
              Text: 7/11/2026
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 00469580
          Numbering:
            – Type: volume
              Value: 63
          Titles:
            – TitleFull: Inquiry (00469580)
              Type: main
ResultId 1