Changing Research Orientations in Paget's Disease of Bone: A Bibliometric Analysis.
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| Title: | Changing Research Orientations in Paget's Disease of Bone: A Bibliometric Analysis. |
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| Authors: | Ha, Lei1 (AUTHOR), Zhu, Jinghui1 (AUTHOR), Wu, Jianhuang1 (AUTHOR) wujianhuang11@csu.edu.cn |
| Source: | Inquiry (00469580). 7/20/2026, Vol. 63, p1-12. 12p. |
| Subject Terms: | *Citation analysis, *Bibliometrics, *Inter-observer reliability, Research funding, Descriptive statistics, Thematic analysis, Medical research, Statistics, Conceptual structures, Osteitis deformans, Data analysis software |
| Abstract: | Introduction: Paget's disease of bone (PDB) has long been studied as a condition characterized by disordered bone remodeling. In recent decades, research has increasingly incorporated molecular, genetic, and systemic perspectives, reflecting a broader understanding of the disease. Despite this apparent expansion, changes in the overall research orientation of the PDB field have not been systematically assessed at the field level. Methods: A bibliometric analysis was performed using PDB-related publications indexed in the Web of Science Core Collection between 1999 and 2025. Publication trends, keyword-based thematic mapping, temporal patterns, and citation indicators were analyzed to examine shifts in research focus. Studies were categorized into three research orientations. These included bone-centered studies, molecular and genetic studies, and systemic and neurological studies. The evolution of these orientations over time was evaluated using descriptive metrics. Results: A total of 963 articles published between 1999 and 2025 were included. The Systemic Orientation Index showed a sustained upward trajectory, indicating a gradual shift of PDB research beyond a predominantly bone-centered framework. In time-adjusted citation analysis, systemic and neurological studies showed the highest mean citations per year at 2.63, compared with 1.46 for both bone-centered and molecular and genetic studies. Conclusions: The findings demonstrate a progressive broadening of PDB research beyond a predominantly skeletal framework. While bone-centered studies continue to form the foundation of the field, molecular, genetic, and systemic approaches are playing an important role in shaping contemporary research on PDB. [ABSTRACT FROM AUTHOR] |
| Copyright of Inquiry (00469580) is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Education Research Complete |
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| Abstract: | Introduction: Paget's disease of bone (PDB) has long been studied as a condition characterized by disordered bone remodeling. In recent decades, research has increasingly incorporated molecular, genetic, and systemic perspectives, reflecting a broader understanding of the disease. Despite this apparent expansion, changes in the overall research orientation of the PDB field have not been systematically assessed at the field level. Methods: A bibliometric analysis was performed using PDB-related publications indexed in the Web of Science Core Collection between 1999 and 2025. Publication trends, keyword-based thematic mapping, temporal patterns, and citation indicators were analyzed to examine shifts in research focus. Studies were categorized into three research orientations. These included bone-centered studies, molecular and genetic studies, and systemic and neurological studies. The evolution of these orientations over time was evaluated using descriptive metrics. Results: A total of 963 articles published between 1999 and 2025 were included. The Systemic Orientation Index showed a sustained upward trajectory, indicating a gradual shift of PDB research beyond a predominantly bone-centered framework. In time-adjusted citation analysis, systemic and neurological studies showed the highest mean citations per year at 2.63, compared with 1.46 for both bone-centered and molecular and genetic studies. Conclusions: The findings demonstrate a progressive broadening of PDB research beyond a predominantly skeletal framework. While bone-centered studies continue to form the foundation of the field, molecular, genetic, and systemic approaches are playing an important role in shaping contemporary research on PDB. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 00469580 |
| DOI: | 10.1177/00469580261469861 |
