Brief Assessment of Parents' Attitudes Toward Testing Minor Children for Hereditary Breast/Ovarian Cancer Genes: Development and Validation of the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS).
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| Title: | Brief Assessment of Parents' Attitudes Toward Testing Minor Children for Hereditary Breast/Ovarian Cancer Genes: Development and Validation of the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS). |
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| Authors: | Peshkin, Beth N., DeMarco, Tiffani A., Garber, Judy E., Valdimarsdottir, Heiddis B., Patenaude, Andrea E., Schneider, Katherine A., Schwartz, Marc D., Tercyak, Kenneth P. |
| Source: | Journal of Pediatric Psychology. Jul2009, Vol. 34 Issue 6, p627-638. 12p. |
| Subject Terms: | *Testing, *Parent attitudes, Genetic research, Genetic counseling, Genetic testing, Minors, Breast cancer diagnosis, Ovarian cancer |
| Abstract: | Objective Predictive genetic testing for hereditary breast/ovarian cancer risk (BRCA1/2 testing) is not recommended for minor children due to its lack of immediate medical benefit and potential psychological risk. Yet, tested mothers are often interested in learning about their children's cancer risks via pediatric BRCA1/2 testing, raising a host of bioethical concerns. However, no reliable or valid tool exists to formally gauge parents' interest in such testing. The aim of this study was to develop and evaluate a new measure for use in genetic research and consultation, known as the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS). Methods After pretest genetic counseling and provision of a blood sample for BRCA1/2 testing, the P-TAS was administered to 187 mothers of children between 8and 21-years-old. The measure was also given to 96 of the mothers' nontested co-parents. Analyses of the factor structure and psychometric properties of the measure were performed in mothers and confirmed in their co-parents. Results The two factors of the P-TAS, labeled Attitudes and Beliefs (Factor 1) and Decision Making and Communication (Factor 2), accounted for 62.9% of the variance and were reliable (Cronbach's coefficient αs = .70 and .90, respectively); the structure and properties were largely confirmed among co-parents. Validity was indicated through its convergence with related constructs. Conclusions This new tool may be integrated into genetic counseling research to better assess parents' attitudes and interests in pediatric BRCA1/2 testing. Such information may help guide ongoing discussions about the appropriateness of testing in adolescent or young adult children. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Pediatric Psychology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Education Research Complete |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: ehh DbLabel: Education Research Complete An: 43569997 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Brief Assessment of Parents' Attitudes Toward Testing Minor Children for Hereditary Breast/Ovarian Cancer Genes: Development and Validation of the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Peshkin%2C+Beth+N%2E%22">Peshkin, Beth N.</searchLink><br /><searchLink fieldCode="AR" term="%22DeMarco%2C+Tiffani+A%2E%22">DeMarco, Tiffani A.</searchLink><br /><searchLink fieldCode="AR" term="%22Garber%2C+Judy+E%2E%22">Garber, Judy E.</searchLink><br /><searchLink fieldCode="AR" term="%22Valdimarsdottir%2C+Heiddis+B%2E%22">Valdimarsdottir, Heiddis B.</searchLink><br /><searchLink fieldCode="AR" term="%22Patenaude%2C+Andrea+E%2E%22">Patenaude, Andrea E.</searchLink><br /><searchLink fieldCode="AR" term="%22Schneider%2C+Katherine+A%2E%22">Schneider, Katherine A.</searchLink><br /><searchLink fieldCode="AR" term="%22Schwartz%2C+Marc+D%2E%22">Schwartz, Marc D.</searchLink><br /><searchLink fieldCode="AR" term="%22Tercyak%2C+Kenneth+P%2E%22">Tercyak, Kenneth P.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Pediatric+Psychology%22">Journal of Pediatric Psychology</searchLink>. Jul2009, Vol. 34 Issue 6, p627-638. 12p. – Name: Subject Label: Subject Terms Group: Su Data: *<searchLink fieldCode="DE" term="%22Testing%22">Testing</searchLink><br />*<searchLink fieldCode="DE" term="%22Parent+attitudes%22">Parent attitudes</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+research%22">Genetic research</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+counseling%22">Genetic counseling</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+testing%22">Genetic testing</searchLink><br /><searchLink fieldCode="DE" term="%22Minors%22">Minors</searchLink><br /><searchLink fieldCode="DE" term="%22Breast+cancer+diagnosis%22">Breast cancer diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Ovarian+cancer%22">Ovarian cancer</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objective Predictive genetic testing for hereditary breast/ovarian cancer risk (BRCA1/2 testing) is not recommended for minor children due to its lack of immediate medical benefit and potential psychological risk. Yet, tested mothers are often interested in learning about their children's cancer risks via pediatric BRCA1/2 testing, raising a host of bioethical concerns. However, no reliable or valid tool exists to formally gauge parents' interest in such testing. The aim of this study was to develop and evaluate a new measure for use in genetic research and consultation, known as the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS). Methods After pretest genetic counseling and provision of a blood sample for BRCA1/2 testing, the P-TAS was administered to 187 mothers of children between 8and 21-years-old. The measure was also given to 96 of the mothers' nontested co-parents. Analyses of the factor structure and psychometric properties of the measure were performed in mothers and confirmed in their co-parents. Results The two factors of the P-TAS, labeled Attitudes and Beliefs (Factor 1) and Decision Making and Communication (Factor 2), accounted for 62.9% of the variance and were reliable (Cronbach's coefficient αs = .70 and .90, respectively); the structure and properties were largely confirmed among co-parents. Validity was indicated through its convergence with related constructs. Conclusions This new tool may be integrated into genetic counseling research to better assess parents' attitudes and interests in pediatric BRCA1/2 testing. Such information may help guide ongoing discussions about the appropriateness of testing in adolescent or young adult children. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Pediatric Psychology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/jpepsy/jsn033 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 627 Subjects: – SubjectFull: Testing Type: general – SubjectFull: Parent attitudes Type: general – SubjectFull: Genetic research Type: general – SubjectFull: Genetic counseling Type: general – SubjectFull: Genetic testing Type: general – SubjectFull: Minors Type: general – SubjectFull: Breast cancer diagnosis Type: general – SubjectFull: Ovarian cancer Type: general Titles: – TitleFull: Brief Assessment of Parents' Attitudes Toward Testing Minor Children for Hereditary Breast/Ovarian Cancer Genes: Development and Validation of the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Peshkin, Beth N. – PersonEntity: Name: NameFull: DeMarco, Tiffani A. – PersonEntity: Name: NameFull: Garber, Judy E. – PersonEntity: Name: NameFull: Valdimarsdottir, Heiddis B. – PersonEntity: Name: NameFull: Patenaude, Andrea E. – PersonEntity: Name: NameFull: Schneider, Katherine A. – PersonEntity: Name: NameFull: Schwartz, Marc D. – PersonEntity: Name: NameFull: Tercyak, Kenneth P. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: Jul2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 01468693 Numbering: – Type: volume Value: 34 – Type: issue Value: 6 Titles: – TitleFull: Journal of Pediatric Psychology Type: main |
| ResultId | 1 |
