Metformin and thymoquinone co‐treatment enhance 5‐fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells.

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Title: Metformin and thymoquinone co‐treatment enhance 5‐fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells.
Authors: Farrash, Wesam F.1 (AUTHOR), Aslam, Akhmed1 (AUTHOR), Almaimani, Riyad2 (AUTHOR), Minshawi, Faisal1 (AUTHOR), Almasmoum, Hussain1 (AUTHOR), Alsaegh, Aiman1 (AUTHOR), Iqbal, Mohammad S.1 (AUTHOR), Tabassum, Aisha1 (AUTHOR), Elzubier, Mohamed E.2 (AUTHOR), El‐Readi, Mahmoud Z.2,3 (AUTHOR), Mahbub, Amani A.1 (AUTHOR), Idris, Shakir1 (AUTHOR), Refaat, Bassem1 (AUTHOR) barefaat@uqu.edu.sa
Source: Biofactors. Jul2023, Vol. 49 Issue 4, p831-848. 18p.
Database: Environment Complete
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  Data: Metformin and thymoquinone co‐treatment enhance 5‐fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells.
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  Data: <searchLink fieldCode="JN" term="%22Biofactors%22">Biofactors</searchLink>. Jul2023, Vol. 49 Issue 4, p831-848. 18p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=eih&AN=170725150
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      – Type: doi
        Value: 10.1002/biof.1947
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      – Code: eng
        Text: English
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        PageCount: 18
        StartPage: 831
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      – TitleFull: Metformin and thymoquinone co‐treatment enhance 5‐fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells.
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            – D: 01
              M: 07
              Text: Jul2023
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              Y: 2023
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