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The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals.

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Title: The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals.
Authors: Henderson, C. J.1,2 (AUTHOR), McLaren, A. W.1,2 (AUTHOR), MacLeod, A. K.3 (AUTHOR), Lin, D.3 (AUTHOR), Cameron, A. R.2,4 (AUTHOR), Chatham, L. R.2,5 (AUTHOR), Moggs, J.2,6 (AUTHOR), Inesta-Vaquera, F.1 (AUTHOR), Thomson, John P.2,7 (AUTHOR), Meehan, Richard R.2,8 (AUTHOR), Chakravarty, P.9 (AUTHOR), Schwarz, M.2,10 (AUTHOR), Wolf, C. Roland1,2 (AUTHOR) c.r.wolf@dundee.ac.uk
Source: Archives of Toxicology. May2025, Vol. 99 Issue 5, p2197-2210. 14p.
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  Data: The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals.
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  Data: <searchLink fieldCode="JN" term="%22Archives+of+Toxicology%22">Archives of Toxicology</searchLink>. May2025, Vol. 99 Issue 5, p2197-2210. 14p.
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        Value: 10.1007/s00204-025-03982-9
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        Text: English
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              Text: May2025
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              Y: 2025
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