The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals. - Henderson, C. J.; McLaren, A. W.; MacLeod, A. K.; Lin, D.; Cameron, A. R.; Chatham, L. R.; Moggs, J.; Inesta-Vaquera, F.; Thomson, John P.; Meehan, Richard R.; Chakravarty, P.; Schwarz, M.; et al. (Archives of Toxicology, 2025)