ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility. - Kohnken, Rebecca; Fossey, Stacey; Buck, Wayne R; Segreti, Jason; Treadway, Jessica; Green, Jonathon; Koshman, Yevgeniya E; Zafiratos, Mark; Mittelstadt, Scott; Blomme, Eric; Foley, Charles M (Toxicological Sciences, 2025)