Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds.

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Title: Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds.
Authors: Carstens, Kelly E.1 (AUTHOR), Gronskaya, Elena2 (AUTHOR), Jäckel, David2 (AUTHOR), Bertoli, Jessica3 (AUTHOR), Cuevas, Kelvin Ramirez3 (AUTHOR), Dorier, Julien4,5 (AUTHOR), Wang, Shan3 (AUTHOR), Lopez-Rodriguez, David3,6,7 (AUTHOR), Shafer, Timothy J.1 (AUTHOR), Zurich, Marie-Gabrielle3,6 (AUTHOR), Pamies, David3,6,8 (AUTHOR) David.pamies@unil.ch
Source: Archives of Toxicology. Jul2025, Vol. 99 Issue 7, p2917-2935. 19p.
Database: Environment Complete
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ISSN:03405761
DOI:10.1007/s00204-025-04043-x