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Structure-based optimization and binding assays for discovery of tau PET radiotracers: synthesis and in vivo evaluation of [11C]Z-3272.

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Title: Structure-based optimization and binding assays for discovery of tau PET radiotracers: synthesis and in vivo evaluation of [11C]Z-3272.
Authors: d'Orchymont, Faustine1 (AUTHOR), Tong, Junchao1 (AUTHOR), Kaplan, Anat Levit2 (AUTHOR), Shoichet, Brian2 (AUTHOR), Mathis, Chester A.3 (AUTHOR), Stehouwer, Jeffrey S.3 (AUTHOR), Vasdev, Neil1,4 (AUTHOR) neil.vasdev@utoronto.ca
Source: Canadian Journal of Chemistry. 2026, Vol. 104 Issue 4, p349-355. 7p.
Database: Environment Complete
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DbLabel: Environment Complete
An: 192672806
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Structure-based optimization and binding assays for discovery of tau PET radiotracers: synthesis and in vivo evaluation of [<superscript>11</superscript>C]Z-3272.
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  Data: <searchLink fieldCode="JN" term="%22Canadian+Journal+of+Chemistry%22">Canadian Journal of Chemistry</searchLink>. 2026, Vol. 104 Issue 4, p349-355. 7p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=eih&AN=192672806
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1139/cjc-2025-0058
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      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 349
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      – TitleFull: Structure-based optimization and binding assays for discovery of tau PET radiotracers: synthesis and in vivo evaluation of [11C]Z-3272.
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            NameFull: d'Orchymont, Faustine
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            NameFull: Tong, Junchao
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            NameFull: Kaplan, Anat Levit
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            NameFull: Shoichet, Brian
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            NameFull: Mathis, Chester A.
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            NameFull: Stehouwer, Jeffrey S.
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            NameFull: Vasdev, Neil
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            – D: 01
              M: 04
              Text: 2026
              Type: published
              Y: 2026
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              Value: 104
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            – TitleFull: Canadian Journal of Chemistry
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