Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-γ/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection

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Title: Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-γ/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection
Authors: Cummings, James F.1 james.cummings@us.army.mil, Spring, Michele D.1, Schwenk, Robert J.1, Ockenhouse, Christian F.1, Kester, Kent E.1, Polhemus, Mark E.1, Walsh, Douglas S.1 dwalsh@wrp-ksm.org, Yoon, In-Kyu1 InkyuYoon@afrims.org, Prosperi, Christine1, Juompan, Laure Y.1, Lanar, David E.1, Krzych, Urszula1, Hall, B. Ted1, Ware, Lisa A.1, Stewart, V. Ann1 astewart@wrp-ksm.org, Williams, Jack1, Dowler, Megan1, Nielsen, Robin K.1, Hillier, Collette J.1 Chillier@arana.com, Giersing, Birgitte K.2 giersingb@ebsi.com
Source: Vaccine. Jul2010, Vol. 28 Issue 31, p5135-5144. 10p.
Database: Environment Complete
Description
ISSN:0264410X
DOI:10.1016/j.vaccine.2009.08.046