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Modeling and optimization of bioethanol production yield from corn starch using response surface methodology.

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Title: Modeling and optimization of bioethanol production yield from corn starch using response surface methodology.
Authors: Alalyani, Salim Rashid Salim1 (AUTHOR), Lakkimsetty, Nageswara Rao1 (AUTHOR) nageswararao@nu.edu.om, Shaik, Feroz2 (AUTHOR), Varghese, M J1 (AUTHOR)
Source: Environment, Development & Sustainability. Sep2025, Vol. 27 Issue 9, p22731-22748. 18p.
Subject Terms: *Cornstarch, *Ethanol as fuel, *Biomass energy, *Mathematical optimization, *Chemical yield, *Renewable natural resources, *Response surfaces (Statistics), *Sustainability
Abstract: The demand for alternate fuels/biofuels is increasing rapidly to counter the adverse economic and environmental impacts created by conventional fossil fuels. The production of biofuels from various natural raw materials is gaining importance due to sustainability from renewable resources. Ethanol is widely used biofuel, manufactured from natural raw materials. In this work, bioethanol was produced from corn starch. Various factors that influence the production of bioethanol such as substrate loading, temperature, pH, reaction time, enzyme titer were studied. The maximum bioethanol yield (97.3%) was achieved at the substrate loading = 40% w/v, temperature = 55 °C, reaction time = 5 h, pH = 6, enzyme titer = 25 IU/mL. A central composite design (CCD) using response surface methodology (RSM) was employed to optimize the influencing factors for the bioethanol production yield. Optimization of these factors was able to achieve 98.3% of bioethanol yield at the process conditions of substrate loading = 30.4 w/v, temperature = 55.8 °C, reaction time = 5.2 h, pH = 5.2, and enzyme titer = 29.2 IU/mL. The experimental optimum values were in good agreement with predicted values from RSM. [ABSTRACT FROM AUTHOR]
Database: Energy & Power Source
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Header DbId: enr
DbLabel: Energy & Power Source
An: 188151260
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  Label: Title
  Group: Ti
  Data: Modeling and optimization of bioethanol production yield from corn starch using response surface methodology.
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  Data: <searchLink fieldCode="AR" term="%22Alalyani%2C+Salim+Rashid+Salim%22">Alalyani, Salim Rashid Salim</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lakkimsetty%2C+Nageswara+Rao%22">Lakkimsetty, Nageswara Rao</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> nageswararao@nu.edu.om</i><br /><searchLink fieldCode="AR" term="%22Shaik%2C+Feroz%22">Shaik, Feroz</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Varghese%2C+M+J%22">Varghese, M J</searchLink><relatesTo>1</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Environment%2C+Development+%26+Sustainability%22">Environment, Development & Sustainability</searchLink>. Sep2025, Vol. 27 Issue 9, p22731-22748. 18p.
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  Group: Su
  Data: *<searchLink fieldCode="DE" term="%22Cornstarch%22">Cornstarch</searchLink><br />*<searchLink fieldCode="DE" term="%22Ethanol+as+fuel%22">Ethanol as fuel</searchLink><br />*<searchLink fieldCode="DE" term="%22Biomass+energy%22">Biomass energy</searchLink><br />*<searchLink fieldCode="DE" term="%22Mathematical+optimization%22">Mathematical optimization</searchLink><br />*<searchLink fieldCode="DE" term="%22Chemical+yield%22">Chemical yield</searchLink><br />*<searchLink fieldCode="DE" term="%22Renewable+natural+resources%22">Renewable natural resources</searchLink><br />*<searchLink fieldCode="DE" term="%22Response+surfaces+%28Statistics%29%22">Response surfaces (Statistics)</searchLink><br />*<searchLink fieldCode="DE" term="%22Sustainability%22">Sustainability</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The demand for alternate fuels/biofuels is increasing rapidly to counter the adverse economic and environmental impacts created by conventional fossil fuels. The production of biofuels from various natural raw materials is gaining importance due to sustainability from renewable resources. Ethanol is widely used biofuel, manufactured from natural raw materials. In this work, bioethanol was produced from corn starch. Various factors that influence the production of bioethanol such as substrate loading, temperature, pH, reaction time, enzyme titer were studied. The maximum bioethanol yield (97.3%) was achieved at the substrate loading = 40% w/v, temperature = 55 °C, reaction time = 5 h, pH = 6, enzyme titer = 25 IU/mL. A central composite design (CCD) using response surface methodology (RSM) was employed to optimize the influencing factors for the bioethanol production yield. Optimization of these factors was able to achieve 98.3% of bioethanol yield at the process conditions of substrate loading = 30.4 w/v, temperature = 55.8 °C, reaction time = 5.2 h, pH = 5.2, and enzyme titer = 29.2 IU/mL. The experimental optimum values were in good agreement with predicted values from RSM. [ABSTRACT FROM AUTHOR]
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10668-023-02990-y
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 18
        StartPage: 22731
    Subjects:
      – SubjectFull: Cornstarch
        Type: general
      – SubjectFull: Ethanol as fuel
        Type: general
      – SubjectFull: Biomass energy
        Type: general
      – SubjectFull: Mathematical optimization
        Type: general
      – SubjectFull: Chemical yield
        Type: general
      – SubjectFull: Renewable natural resources
        Type: general
      – SubjectFull: Response surfaces (Statistics)
        Type: general
      – SubjectFull: Sustainability
        Type: general
    Titles:
      – TitleFull: Modeling and optimization of bioethanol production yield from corn starch using response surface methodology.
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Alalyani, Salim Rashid Salim
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            NameFull: Lakkimsetty, Nageswara Rao
      – PersonEntity:
          Name:
            NameFull: Shaik, Feroz
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            NameFull: Varghese, M J
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            – D: 01
              M: 09
              Text: Sep2025
              Type: published
              Y: 2025
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              Value: 1387585X
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              Value: 27
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Environment, Development & Sustainability
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