Copper-doped titanium dioxide nanoparticles decorated on 2D-hexagonal boron nitride nanosheets for susceptible electrochemical detection of an anti-cancer drug in environmental and biological samples.
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| Title: | Copper-doped titanium dioxide nanoparticles decorated on 2D-hexagonal boron nitride nanosheets for susceptible electrochemical detection of an anti-cancer drug in environmental and biological samples. |
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| Authors: | Prajapati, Jyoti1 (AUTHOR) prajapatijyoti96@gmail.com, Gautam, Ravindra Kumar1 (AUTHOR) ravindragautam1987@gmail.com, Tiwari, Ida1 (AUTHOR) idatiwari@bhu.ac.in |
| Source: | Environmental Science & Pollution Research. Feb2026, Vol. 33 Issue 6, p2017-2031. 15p. |
| Subject Terms: | *Chlorambucil, *Titanium dioxide nanoparticles, *Antineoplastic agents, *Electrochemical sensors, *Voltammetry technique, *Two-dimensional materials (Nanotechnology), *Electrodes |
| Abstract: | Chlorambucil (CML) cures chronic lymphatic leukemia (white blood cell cancer). A high dose of CML can cause several side effects like bone marrow suppression, anemia, peripheral neuropathy, and infertility in the human body. In this research, we have synthesized a nanocomposite based on copper-doped titanium dioxide (CuTiO2) adorned with 2D hexagonal boron nitride (CuTiO2@BN) for the efficient electrochemical detection of CML. A series of characterization techniques FT-IR, XRD, Raman spectroscopy, SEM, TEM, EDAX XPS, and electrochemical characterization were used to analyze the CuTiO2@BN nanocomposite structural and morphological compositions. The sensing performance of the CuTiO2@BN modified GCE for CML detection has been assessed using voltammetry methods. The chronoamperometry technique analyzed the kinetics of the electrochemical oxidation of CML at CuTiO2@BN/GCE. The CuTiO2@BN-based glassy carbon electrode (GCE) has a synergetic electro-catalytic effect on CML oxidation due to its many active sites, enhanced surface area, fast charge transfer, and numerous defects. For the detection of CML, the suggested electrochemical sensor exhibits excellent selectivity, low limit of detection (LOD) as found 5.0 nM, wide linear ranges (0.02–8000 µM), and quick reaction times. [ABSTRACT FROM AUTHOR] |
| Database: | Energy & Power Source |
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| Header | DbId: enr DbLabel: Energy & Power Source An: 192089297 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Copper-doped titanium dioxide nanoparticles decorated on 2D-hexagonal boron nitride nanosheets for susceptible electrochemical detection of an anti-cancer drug in environmental and biological samples. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Prajapati%2C+Jyoti%22">Prajapati, Jyoti</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> prajapatijyoti96@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Gautam%2C+Ravindra+Kumar%22">Gautam, Ravindra Kumar</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> ravindragautam1987@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Tiwari%2C+Ida%22">Tiwari, Ida</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> idatiwari@bhu.ac.in</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Environmental+Science+%26+Pollution+Research%22">Environmental Science & Pollution Research</searchLink>. Feb2026, Vol. 33 Issue 6, p2017-2031. 15p. – Name: Subject Label: Subject Terms Group: Su Data: *<searchLink fieldCode="DE" term="%22Chlorambucil%22">Chlorambucil</searchLink><br />*<searchLink fieldCode="DE" term="%22Titanium+dioxide+nanoparticles%22">Titanium dioxide nanoparticles</searchLink><br />*<searchLink fieldCode="DE" term="%22Antineoplastic+agents%22">Antineoplastic agents</searchLink><br />*<searchLink fieldCode="DE" term="%22Electrochemical+sensors%22">Electrochemical sensors</searchLink><br />*<searchLink fieldCode="DE" term="%22Voltammetry+technique%22">Voltammetry technique</searchLink><br />*<searchLink fieldCode="DE" term="%22Two-dimensional+materials+%28Nanotechnology%29%22">Two-dimensional materials (Nanotechnology)</searchLink><br />*<searchLink fieldCode="DE" term="%22Electrodes%22">Electrodes</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Chlorambucil (CML) cures chronic lymphatic leukemia (white blood cell cancer). A high dose of CML can cause several side effects like bone marrow suppression, anemia, peripheral neuropathy, and infertility in the human body. In this research, we have synthesized a nanocomposite based on copper-doped titanium dioxide (CuTiO2) adorned with 2D hexagonal boron nitride (CuTiO2@BN) for the efficient electrochemical detection of CML. A series of characterization techniques FT-IR, XRD, Raman spectroscopy, SEM, TEM, EDAX XPS, and electrochemical characterization were used to analyze the CuTiO2@BN nanocomposite structural and morphological compositions. The sensing performance of the CuTiO2@BN modified GCE for CML detection has been assessed using voltammetry methods. The chronoamperometry technique analyzed the kinetics of the electrochemical oxidation of CML at CuTiO2@BN/GCE. The CuTiO2@BN-based glassy carbon electrode (GCE) has a synergetic electro-catalytic effect on CML oxidation due to its many active sites, enhanced surface area, fast charge transfer, and numerous defects. For the detection of CML, the suggested electrochemical sensor exhibits excellent selectivity, low limit of detection (LOD) as found 5.0 nM, wide linear ranges (0.02–8000 µM), and quick reaction times. [ABSTRACT FROM AUTHOR] |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=enr&AN=192089297 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s11356-024-33642-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 15 StartPage: 2017 Subjects: – SubjectFull: Chlorambucil Type: general – SubjectFull: Titanium dioxide nanoparticles Type: general – SubjectFull: Antineoplastic agents Type: general – SubjectFull: Electrochemical sensors Type: general – SubjectFull: Voltammetry technique Type: general – SubjectFull: Two-dimensional materials (Nanotechnology) Type: general – SubjectFull: Electrodes Type: general Titles: – TitleFull: Copper-doped titanium dioxide nanoparticles decorated on 2D-hexagonal boron nitride nanosheets for susceptible electrochemical detection of an anti-cancer drug in environmental and biological samples. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Prajapati, Jyoti – PersonEntity: Name: NameFull: Gautam, Ravindra Kumar – PersonEntity: Name: NameFull: Tiwari, Ida IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 02 Text: Feb2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 09441344 Numbering: – Type: volume Value: 33 – Type: issue Value: 6 Titles: – TitleFull: Environmental Science & Pollution Research Type: main |
| ResultId | 1 |
