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Validation of the estimation of 192Ir production rates in wires from natural iridium-platinum in research reactors.

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Title: Validation of the estimation of 192Ir production rates in wires from natural iridium-platinum in research reactors.
Authors: Tataje, P.1,2 (AUTHOR) ptataje@ipen.gob.pe, Ticona, B.1 (AUTHOR), Daza, S.1 (AUTHOR), Adauto, Anais3 (AUTHOR)
Source: Journal of Radioanalytical & Nuclear Chemistry. Apr2026, Vol. 335 Issue 4, p2915-2922. 8p.
Subject Terms: *Research reactors, *Iridium, *Radioisotope brachytherapy, *Germanium detectors, *Nuclear activation analysis, *Gamma ray spectroscopy, *Neutron flux
Abstract: Iridium-192 is a crucial radionuclide, extensively used in brachytherapy for cancer treatment. The accurate estimation of the production rate of 192Ir is critical for optimizing the manufacture of brachytherapy sources in nuclear reactors and ensuring their dosimetric quality. A rigorous calculation of this rate makes it possible to define irradiation times, guarantee the activity required at the clinical moment, and reduce variations in production, all of which have a direct impact on therapeutic efficacy. This study evaluates the production rate of 192Ir in wires composed of natural iridium-platinum alloys when irradiated in research reactors. The methodology incorporates the Hϕgdhal convention, taking into account neutron flux distribution, cross-section data, self-shielding factor, and resonance integral estimations. Experimental validation is carried out through neutron activation analysis and gamma spectroscopy using a HPGe detector. The results demonstrate a strong correlation between theoretical calculations and experimental measurements, providing a reliable framework for optimizing 192Ir production. [ABSTRACT FROM AUTHOR]
Database: Energy & Power Source
FullText Text:
  Availability: 0
Header DbId: enr
DbLabel: Energy & Power Source
An: 193284210
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Validation of the estimation of <superscript>192</superscript>Ir production rates in wires from natural iridium-platinum in research reactors.
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  Data: <searchLink fieldCode="AR" term="%22Tataje%2C+P%2E%22">Tataje, P.</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> ptataje@ipen.gob.pe</i><br /><searchLink fieldCode="AR" term="%22Ticona%2C+B%2E%22">Ticona, B.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Daza%2C+S%2E%22">Daza, S.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Adauto%2C+Anais%22">Adauto, Anais</searchLink><relatesTo>3</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Radioanalytical+%26+Nuclear+Chemistry%22">Journal of Radioanalytical & Nuclear Chemistry</searchLink>. Apr2026, Vol. 335 Issue 4, p2915-2922. 8p.
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  Data: *<searchLink fieldCode="DE" term="%22Research+reactors%22">Research reactors</searchLink><br />*<searchLink fieldCode="DE" term="%22Iridium%22">Iridium</searchLink><br />*<searchLink fieldCode="DE" term="%22Radioisotope+brachytherapy%22">Radioisotope brachytherapy</searchLink><br />*<searchLink fieldCode="DE" term="%22Germanium+detectors%22">Germanium detectors</searchLink><br />*<searchLink fieldCode="DE" term="%22Nuclear+activation+analysis%22">Nuclear activation analysis</searchLink><br />*<searchLink fieldCode="DE" term="%22Gamma+ray+spectroscopy%22">Gamma ray spectroscopy</searchLink><br />*<searchLink fieldCode="DE" term="%22Neutron+flux%22">Neutron flux</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Iridium-192 is a crucial radionuclide, extensively used in brachytherapy for cancer treatment. The accurate estimation of the production rate of 192Ir is critical for optimizing the manufacture of brachytherapy sources in nuclear reactors and ensuring their dosimetric quality. A rigorous calculation of this rate makes it possible to define irradiation times, guarantee the activity required at the clinical moment, and reduce variations in production, all of which have a direct impact on therapeutic efficacy. This study evaluates the production rate of 192Ir in wires composed of natural iridium-platinum alloys when irradiated in research reactors. The methodology incorporates the Hϕgdhal convention, taking into account neutron flux distribution, cross-section data, self-shielding factor, and resonance integral estimations. Experimental validation is carried out through neutron activation analysis and gamma spectroscopy using a HPGe detector. The results demonstrate a strong correlation between theoretical calculations and experimental measurements, providing a reliable framework for optimizing 192Ir production. [ABSTRACT FROM AUTHOR]
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=enr&AN=193284210
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10967-026-10783-6
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 2915
    Subjects:
      – SubjectFull: Research reactors
        Type: general
      – SubjectFull: Iridium
        Type: general
      – SubjectFull: Radioisotope brachytherapy
        Type: general
      – SubjectFull: Germanium detectors
        Type: general
      – SubjectFull: Nuclear activation analysis
        Type: general
      – SubjectFull: Gamma ray spectroscopy
        Type: general
      – SubjectFull: Neutron flux
        Type: general
    Titles:
      – TitleFull: Validation of the estimation of 192Ir production rates in wires from natural iridium-platinum in research reactors.
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            NameFull: Tataje, P.
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            NameFull: Ticona, B.
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            NameFull: Daza, S.
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            – D: 01
              M: 04
              Text: Apr2026
              Type: published
              Y: 2026
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              Value: 335
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              Value: 4
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            – TitleFull: Journal of Radioanalytical & Nuclear Chemistry
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