Maternal Exposure to Occupational Asthmagens during Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development
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| Title: | Maternal Exposure to Occupational Asthmagens during Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development |
|---|---|
| Language: | English |
| Authors: | Singer, Alison B., Windham, Gayle C., Croen, Lisa A., Daniels, Julie L., Lee, Brian K., Qian, Yinge, Schendel, Diana E., Fallin, M. Daniele, Burstyn, Igor |
| Source: | Journal of Autism and Developmental Disorders. Nov 2016 46(11):3458-3468. |
| Availability: | Springer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: service-ny@springer.com; Web site: http://www.springerlink.com |
| Peer Reviewed: | Y |
| Page Count: | 11 |
| Publication Date: | 2016 |
| Sponsoring Agency: | National Institute of Environmental Health Sciences (NIEHS) (NIH) Centers for Disease Control and Prevention (DHHS/PHS) |
| Contract Number: | T32ES007018 U10DD000180 U10DD000181 U10DD000182 U10DD000183 U10DD000184 U10DD000498 |
| Document Type: | Journal Articles Reports - Research |
| Descriptors: | Autism, Pervasive Developmental Disorders, Mothers, Prenatal Influences, Diseases, At Risk Persons, Hazardous Materials, Work Environment, Young Children, Developmental Disabilities, Cognitive Ability, Motor Development, Observation, Diagnostic Tests, Interviews, Coding, Statistical Analysis, Individual Characteristics, Correlation, Regression (Statistics) |
| Geographic Terms: | California, Colorado, Georgia, Maryland, North Carolina, Pennsylvania |
| Assessment and Survey Identifiers: | Mullen Scales of Early Learning, Autism Diagnostic Observation Schedule |
| DOI: | 10.1007/s10803-016-2882-6 |
| ISSN: | 0162-3257 |
| Abstract: | Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96-2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD. |
| Abstractor: | As Provided |
| Number of References: | 51 |
| Entry Date: | 2016 |
| Accession Number: | EJ1117523 |
| Database: | ERIC |
| Abstract: | Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96-2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD. |
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| ISSN: | 0162-3257 |
| DOI: | 10.1007/s10803-016-2882-6 |
