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An Interdisciplinary Course on Computer-Aided Drug Discovery to Broaden Student Participation in Original Scientific Research

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Title: An Interdisciplinary Course on Computer-Aided Drug Discovery to Broaden Student Participation in Original Scientific Research
Language: English
Authors: Christopher Stratton, Avery Christensen, Chelsey Jordan, Brian A. Salvatore, Elahe Mahdavian (ORCID 0000-0003-1117-9117)
Source: Biochemistry and Molecular Biology Education. 2024 52(3):276-290.
Availability: Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us
Peer Reviewed: Y
Page Count: 15
Publication Date: 2024
Document Type: Journal Articles
Reports - Descriptive
Descriptors: Educational Technology, Computer Assisted Instruction, Science Instruction, Drug Therapy, COVID-19, Pandemics, Active Learning, Student Research, Research Skills, Interdisciplinary Approach, Chemistry, Biology, Computer Science
Geographic Terms: Louisiana
DOI: 10.1002/bmb.21811
ISSN: 1470-8175
1539-3429
Abstract: We present a new highly interdisciplinary project-based course in computer aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to-face summer research program sponsored by the Louisiana Biomedical Research Network (LBRN). The course integrates guided research and educational experiences for chemistry, biology, and computer science students. We implement research-based methods with publicly available tools in bioinformatics and molecular modeling to identify and prioritize promising antiviral drug candidates for COVID-19. The purpose of this course is three-fold: I. Implement an active learning and inclusive pedagogy that fosters student engagement and research mindset; II. Develop student interdisciplinary research skills that are highly beneficial in a broader scientific context; III. Demonstrate that pedagogical shifts (initially incurred during the COVID-19 pandemic) can furnish longer-term instructional benefits. The course, which has now been successfully taught a total of five times, incorporates four modules, including lectures/discussions, live demos, inquiry-based assignments, and science communication.
Abstractor: As Provided
Entry Date: 2024
Accession Number: EJ1425258
Database: ERIC
FullText Text:
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  Data: An Interdisciplinary Course on Computer-Aided Drug Discovery to Broaden Student Participation in Original Scientific Research
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  Data: <searchLink fieldCode="AR" term="%22Christopher+Stratton%22">Christopher Stratton</searchLink><br /><searchLink fieldCode="AR" term="%22Avery+Christensen%22">Avery Christensen</searchLink><br /><searchLink fieldCode="AR" term="%22Chelsey+Jordan%22">Chelsey Jordan</searchLink><br /><searchLink fieldCode="AR" term="%22Brian+A%2E+Salvatore%22">Brian A. Salvatore</searchLink><br /><searchLink fieldCode="AR" term="%22Elahe+Mahdavian%22">Elahe Mahdavian</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0003-1117-9117">0000-0003-1117-9117</externalLink>)
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  Data: <searchLink fieldCode="SO" term="%22Biochemistry+and+Molecular+Biology+Education%22"><i>Biochemistry and Molecular Biology Education</i></searchLink>. 2024 52(3):276-290.
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  Data: Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us
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  Data: Y
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  Data: 15
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  Data: Journal Articles<br />Reports - Descriptive
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  Data: <searchLink fieldCode="DE" term="%22Educational+Technology%22">Educational Technology</searchLink><br /><searchLink fieldCode="DE" term="%22Computer+Assisted+Instruction%22">Computer Assisted Instruction</searchLink><br /><searchLink fieldCode="DE" term="%22Science+Instruction%22">Science Instruction</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+Therapy%22">Drug Therapy</searchLink><br /><searchLink fieldCode="DE" term="%22COVID-19%22">COVID-19</searchLink><br /><searchLink fieldCode="DE" term="%22Pandemics%22">Pandemics</searchLink><br /><searchLink fieldCode="DE" term="%22Active+Learning%22">Active Learning</searchLink><br /><searchLink fieldCode="DE" term="%22Student+Research%22">Student Research</searchLink><br /><searchLink fieldCode="DE" term="%22Research+Skills%22">Research Skills</searchLink><br /><searchLink fieldCode="DE" term="%22Interdisciplinary+Approach%22">Interdisciplinary Approach</searchLink><br /><searchLink fieldCode="DE" term="%22Chemistry%22">Chemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Biology%22">Biology</searchLink><br /><searchLink fieldCode="DE" term="%22Computer+Science%22">Computer Science</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Louisiana%22">Louisiana</searchLink>
– Name: DOI
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  Data: 10.1002/bmb.21811
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  Data: 1470-8175<br />1539-3429
– Name: Abstract
  Label: Abstract
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  Data: We present a new highly interdisciplinary project-based course in computer aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to-face summer research program sponsored by the Louisiana Biomedical Research Network (LBRN). The course integrates guided research and educational experiences for chemistry, biology, and computer science students. We implement research-based methods with publicly available tools in bioinformatics and molecular modeling to identify and prioritize promising antiviral drug candidates for COVID-19. The purpose of this course is three-fold: I. Implement an active learning and inclusive pedagogy that fosters student engagement and research mindset; II. Develop student interdisciplinary research skills that are highly beneficial in a broader scientific context; III. Demonstrate that pedagogical shifts (initially incurred during the COVID-19 pandemic) can furnish longer-term instructional benefits. The course, which has now been successfully taught a total of five times, incorporates four modules, including lectures/discussions, live demos, inquiry-based assignments, and science communication.
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        Value: 10.1002/bmb.21811
    Languages:
      – Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 15
        StartPage: 276
    Subjects:
      – SubjectFull: Educational Technology
        Type: general
      – SubjectFull: Computer Assisted Instruction
        Type: general
      – SubjectFull: Science Instruction
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      – SubjectFull: Drug Therapy
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      – SubjectFull: Pandemics
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      – SubjectFull: Active Learning
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      – SubjectFull: Student Research
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      – SubjectFull: Research Skills
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      – SubjectFull: Interdisciplinary Approach
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      – SubjectFull: Chemistry
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      – SubjectFull: Biology
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      – SubjectFull: Computer Science
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      – SubjectFull: Louisiana
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    Titles:
      – TitleFull: An Interdisciplinary Course on Computer-Aided Drug Discovery to Broaden Student Participation in Original Scientific Research
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            NameFull: Christopher Stratton
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            NameFull: Chelsey Jordan
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            NameFull: Brian A. Salvatore
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            NameFull: Elahe Mahdavian
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            – TitleFull: Biochemistry and Molecular Biology Education
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