View in EDS

Updating Dimedone--The Humble Hero of the Organic Laboratory

Saved in:
Bibliographic Details
Title: Updating Dimedone--The Humble Hero of the Organic Laboratory
Language: English
Authors: Alexander J. Wright, Dave Colclough, Hazel Harris, Stefano C. G. Biagini (ORCID 0000-0002-4713-5127)
Source: Journal of Chemical Education. 2023 100(8):3025-3028.
Availability: Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Peer Reviewed: Y
Page Count: 4
Publication Date: 2023
Document Type: Journal Articles
Reports - Descriptive
Education Level: Higher Education
Postsecondary Education
Descriptors: Science Instruction, Science Laboratories, Organic Chemistry, Undergraduate Study, College Science, Spectroscopy, Hands on Science, Science Experiments, Laboratory Experiments
ISSN: 0021-9584
1938-1328
Abstract: In this paper, we present a concise and technique-heavy route to the synthesis of dimedone for a second-year organic chemistry curriculum. Our preparation of dimedone guides students through a Michael addition followed by a Dieckmann cyclization, basic ester hydrolysis, and thermal decarboxylation, while allowing time for mechanistic discussion and analysis of the product. The wide variety of techniques covered led this to be a pedagogically diverse experiment. This task is thoroughly tested and suitable for a 6 hour laboratory class (with a 1 hour lunch break) or two 3 hour stand-alone sessions.
Abstractor: As Provided
Entry Date: 2024
Accession Number: EJ1444500
Database: ERIC
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://eric.ed.gov/contentdelivery/servlet/ERICServlet?accno=EJ1444500
    Name: ERIC Full Text
    Category: fullText
    Text: Full Text from ERIC
Header DbId: eric
DbLabel: ERIC
An: EJ1444500
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Updating Dimedone--The Humble Hero of the Organic Laboratory
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Alexander+J%2E+Wright%22">Alexander J. Wright</searchLink><br /><searchLink fieldCode="AR" term="%22Dave+Colclough%22">Dave Colclough</searchLink><br /><searchLink fieldCode="AR" term="%22Hazel+Harris%22">Hazel Harris</searchLink><br /><searchLink fieldCode="AR" term="%22Stefano+C%2E+G%2E+Biagini%22">Stefano C. G. Biagini</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0002-4713-5127">0000-0002-4713-5127</externalLink>)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="SO" term="%22Journal+of+Chemical+Education%22"><i>Journal of Chemical Education</i></searchLink>. 2023 100(8):3025-3028.
– Name: Avail
  Label: Availability
  Group: Avail
  Data: Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
– Name: PeerReviewed
  Label: Peer Reviewed
  Group: SrcInfo
  Data: Y
– Name: Pages
  Label: Page Count
  Group: Src
  Data: 4
– Name: DatePubCY
  Label: Publication Date
  Group: Date
  Data: 2023
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: Journal Articles<br />Reports - Descriptive
– Name: Audience
  Label: Education Level
  Group: Audnce
  Data: <searchLink fieldCode="EL" term="%22Higher+Education%22">Higher Education</searchLink><br /><searchLink fieldCode="EL" term="%22Postsecondary+Education%22">Postsecondary Education</searchLink>
– Name: Subject
  Label: Descriptors
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Science+Instruction%22">Science Instruction</searchLink><br /><searchLink fieldCode="DE" term="%22Science+Laboratories%22">Science Laboratories</searchLink><br /><searchLink fieldCode="DE" term="%22Organic+Chemistry%22">Organic Chemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Undergraduate+Study%22">Undergraduate Study</searchLink><br /><searchLink fieldCode="DE" term="%22College+Science%22">College Science</searchLink><br /><searchLink fieldCode="DE" term="%22Spectroscopy%22">Spectroscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Hands+on+Science%22">Hands on Science</searchLink><br /><searchLink fieldCode="DE" term="%22Science+Experiments%22">Science Experiments</searchLink><br /><searchLink fieldCode="DE" term="%22Laboratory+Experiments%22">Laboratory Experiments</searchLink>
– Name: ISSN
  Label: ISSN
  Group: ISSN
  Data: 0021-9584<br />1938-1328
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: In this paper, we present a concise and technique-heavy route to the synthesis of dimedone for a second-year organic chemistry curriculum. Our preparation of dimedone guides students through a Michael addition followed by a Dieckmann cyclization, basic ester hydrolysis, and thermal decarboxylation, while allowing time for mechanistic discussion and analysis of the product. The wide variety of techniques covered led this to be a pedagogically diverse experiment. This task is thoroughly tested and suitable for a 6 hour laboratory class (with a 1 hour lunch break) or two 3 hour stand-alone sessions.
– Name: AbstractInfo
  Label: Abstractor
  Group: Ab
  Data: As Provided
– Name: DateEntry
  Label: Entry Date
  Group: Date
  Data: 2024
– Name: AN
  Label: Accession Number
  Group: ID
  Data: EJ1444500
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=eric&AN=EJ1444500
RecordInfo BibRecord:
  BibEntity:
    Languages:
      – Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 4
        StartPage: 3025
    Subjects:
      – SubjectFull: Science Instruction
        Type: general
      – SubjectFull: Science Laboratories
        Type: general
      – SubjectFull: Organic Chemistry
        Type: general
      – SubjectFull: Undergraduate Study
        Type: general
      – SubjectFull: College Science
        Type: general
      – SubjectFull: Spectroscopy
        Type: general
      – SubjectFull: Hands on Science
        Type: general
      – SubjectFull: Science Experiments
        Type: general
      – SubjectFull: Laboratory Experiments
        Type: general
    Titles:
      – TitleFull: Updating Dimedone--The Humble Hero of the Organic Laboratory
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Alexander J. Wright
      – PersonEntity:
          Name:
            NameFull: Dave Colclough
      – PersonEntity:
          Name:
            NameFull: Hazel Harris
      – PersonEntity:
          Name:
            NameFull: Stefano C. G. Biagini
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 08
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 0021-9584
            – Type: issn-electronic
              Value: 1938-1328
          Numbering:
            – Type: volume
              Value: 100
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Journal of Chemical Education
              Type: main
ResultId 1