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A Systematic Approach to Explore the Rigor of Applied Behavioral Pharmacology Research

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Title: A Systematic Approach to Explore the Rigor of Applied Behavioral Pharmacology Research
Language: English
Authors: Nazurah Khokhar (ORCID 0000-0002-5482-1491), Alison D. Cox (ORCID 0000-0001-5396-6122), Autumn Kozluk
Source: Review Journal of Autism and Developmental Disorders. 2025 12(2):380-396.
Availability: Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/
Peer Reviewed: Y
Page Count: 17
Publication Date: 2025
Document Type: Journal Articles
Information Analyses
Descriptors: Behavioral Science Research, Pharmacology, Behavior Problems, Intellectual Disability, Developmental Disabilities, Clinical Diagnosis, Intervention, Behavior Modification, Drug Therapy, Scores, Research Methodology, Barriers
DOI: 10.1007/s40489-023-00400-7
ISSN: 2195-7177
2195-7185
Abstract: Applied behavioral pharmacology explores how drugs may influence problem behavior in persons with intellectual and developmental disability (IDD). A comprehensive review was conducted featuring single-case experimental designs in the domain of applied behavioral pharmacology to evaluate and report on study quality. Studies included in the review featured participants with a diagnosis of IDD, with problem behavior as the intervention target, and who were receiving psychotropic medications to address problem behavior. Fifty-five articles met criteria and were scored using a 20-item literature-informed Quality Indicator Checklist. Total checklist scores ranged between 32 and 81% which suggest room for improvement regarding the methodological rigor of research in this domain. Barriers and possible solutions to improving study quality are discussed.
Abstractor: As Provided
Entry Date: 2025
Accession Number: EJ1473364
Database: ERIC
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  Data: A Systematic Approach to Explore the Rigor of Applied Behavioral Pharmacology Research
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  Data: <searchLink fieldCode="AR" term="%22Nazurah+Khokhar%22">Nazurah Khokhar</searchLink> (ORCID <externalLink term="http://orcid.org/0000-0002-5482-1491">0000-0002-5482-1491</externalLink>)<br /><searchLink fieldCode="AR" term="%22Alison+D%2E+Cox%22">Alison D. Cox</searchLink> (ORCID <externalLink term="http://orcid.org/0000-0001-5396-6122">0000-0001-5396-6122</externalLink>)<br /><searchLink fieldCode="AR" term="%22Autumn+Kozluk%22">Autumn Kozluk</searchLink>
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  Data: <searchLink fieldCode="SO" term="%22Review+Journal+of+Autism+and+Developmental+Disorders%22"><i>Review Journal of Autism and Developmental Disorders</i></searchLink>. 2025 12(2):380-396.
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  Data: Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/
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  Data: Applied behavioral pharmacology explores how drugs may influence problem behavior in persons with intellectual and developmental disability (IDD). A comprehensive review was conducted featuring single-case experimental designs in the domain of applied behavioral pharmacology to evaluate and report on study quality. Studies included in the review featured participants with a diagnosis of IDD, with problem behavior as the intervention target, and who were receiving psychotropic medications to address problem behavior. Fifty-five articles met criteria and were scored using a 20-item literature-informed Quality Indicator Checklist. Total checklist scores ranged between 32 and 81% which suggest room for improvement regarding the methodological rigor of research in this domain. Barriers and possible solutions to improving study quality are discussed.
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      – Text: English
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      – SubjectFull: Behavior Problems
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      – SubjectFull: Drug Therapy
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      – SubjectFull: Research Methodology
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      – SubjectFull: Barriers
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      – TitleFull: A Systematic Approach to Explore the Rigor of Applied Behavioral Pharmacology Research
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