Substance Use in Military Personnel: Associations with Combat Exposure, Moral Injury, Posttraumatic Stress Disorder and Pain

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Title: Substance Use in Military Personnel: Associations with Combat Exposure, Moral Injury, Posttraumatic Stress Disorder and Pain
Language: English
Authors: Michelle L. Kelley (ORCID 0000-0003-3643-0419), Jeffrey M. Gabelmann (ORCID 0000-0002-3376-8134), Megan Strowger (ORCID 0000-0002-8476-5099), John Hearton (ORCID 0009-0002-8918-9550), Folly Folivi (ORCID 0000-0003-1419-980X), Adrian J. Bravo (ORCID 0000-0002-4630-6449), Jinjoo Noh, Kristin Kuskye, William Haber, Adam P. McGuire (ORCID 0000-0002-4512-1207)
Source: Journal of Drug Education. 2026 55(1):3-20.
Availability: SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: https://sagepub.com
Peer Reviewed: Y
Page Count: 18
Publication Date: 2026
Document Type: Journal Articles
Reports - Research
Descriptors: Substance Abuse, Posttraumatic Stress Disorder, Pain, Military Personnel, Psychological Patterns
DOI: 10.1177/00472379251394435
ISSN: 0047-2379
1541-4159
Abstract: Background: Prior research suggests that military personnel endorse higher rates of prescription drug misuse, cannabis, and heavy alcohol use than civilians. Factors related to substance use may differ for military personnel compared to civilians. In the present study, we examined whether combat exposure, moral injury, posttraumatic stress disorder (PTSD), and pain were associated with military personnel's self-reports of misuse of prescription opiates, prescription sedatives, both prescription opiates and sedatives, cannabis use, and hazardous alcohol consumption. Method: Participants were a community sample of 238 U.S. military personnel who had deployed one or more times (71.0% males; M =33.3 years; SD =3.2). Results: In our sample, rates of past week misuse were as follows: 21.0% prescription opiates, 25.6% prescription sedatives, 16.4% both prescription opiates and sedative medications. With respect to cannabis use and alcohol consumption, 14.7% reported past-week cannabis use and 46.2% participants reported hazardous alcohol consumption above suggested clinical cut-offs. In multivariable multinomial logistic regression analyses, combat exposure and moral injury were uniquely associated with a greater likelihood of misusing prescription opiates, sedatives, and both opiates and sedatives versus no misuse. Higher PTSD symptoms scores were uniquely associated with past week cannabis use versus no use. Further, greater combat exposure was uniquely associated with a greater likelihood of engaging in hazardous alcohol use. Conclusions: These results suggest that distinct psychosocial factors may differentially impact substance use among military personnel. Findings indicate the importance of assessing combat exposure, moral injury, PTSD, and pain to better understand substance use and treatment of military personnel.
Abstractor: As Provided
Entry Date: 2026
Accession Number: EJ1496388
Database: ERIC
FullText Text:
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  Data: Substance Use in Military Personnel: Associations with Combat Exposure, Moral Injury, Posttraumatic Stress Disorder and Pain
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  Data: English
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  Data: <searchLink fieldCode="AR" term="%22Michelle+L%2E+Kelley%22">Michelle L. Kelley</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0003-3643-0419">0000-0003-3643-0419</externalLink>)<br /><searchLink fieldCode="AR" term="%22Jeffrey+M%2E+Gabelmann%22">Jeffrey M. Gabelmann</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0002-3376-8134">0000-0002-3376-8134</externalLink>)<br /><searchLink fieldCode="AR" term="%22Megan+Strowger%22">Megan Strowger</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0002-8476-5099">0000-0002-8476-5099</externalLink>)<br /><searchLink fieldCode="AR" term="%22John+Hearton%22">John Hearton</searchLink> (ORCID <externalLink term="https://orcid.org/0009-0002-8918-9550">0009-0002-8918-9550</externalLink>)<br /><searchLink fieldCode="AR" term="%22Folly+Folivi%22">Folly Folivi</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0003-1419-980X">0000-0003-1419-980X</externalLink>)<br /><searchLink fieldCode="AR" term="%22Adrian+J%2E+Bravo%22">Adrian J. Bravo</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0002-4630-6449">0000-0002-4630-6449</externalLink>)<br /><searchLink fieldCode="AR" term="%22Jinjoo+Noh%22">Jinjoo Noh</searchLink><br /><searchLink fieldCode="AR" term="%22Kristin+Kuskye%22">Kristin Kuskye</searchLink><br /><searchLink fieldCode="AR" term="%22William+Haber%22">William Haber</searchLink><br /><searchLink fieldCode="AR" term="%22Adam+P%2E+McGuire%22">Adam P. McGuire</searchLink> (ORCID <externalLink term="https://orcid.org/0000-0002-4512-1207">0000-0002-4512-1207</externalLink>)
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  Data: <searchLink fieldCode="SO" term="%22Journal+of+Drug+Education%22"><i>Journal of Drug Education</i></searchLink>. 2026 55(1):3-20.
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  Data: SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: https://sagepub.com
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  Data: Y
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  Data: 18
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  Data: 2026
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  Data: Journal Articles<br />Reports - Research
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  Data: <searchLink fieldCode="DE" term="%22Substance+Abuse%22">Substance Abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Posttraumatic+Stress+Disorder%22">Posttraumatic Stress Disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Pain%22">Pain</searchLink><br /><searchLink fieldCode="DE" term="%22Military+Personnel%22">Military Personnel</searchLink><br /><searchLink fieldCode="DE" term="%22Psychological+Patterns%22">Psychological Patterns</searchLink>
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  Data: 10.1177/00472379251394435
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  Data: 0047-2379<br />1541-4159
– Name: Abstract
  Label: Abstract
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  Data: Background: Prior research suggests that military personnel endorse higher rates of prescription drug misuse, cannabis, and heavy alcohol use than civilians. Factors related to substance use may differ for military personnel compared to civilians. In the present study, we examined whether combat exposure, moral injury, posttraumatic stress disorder (PTSD), and pain were associated with military personnel's self-reports of misuse of prescription opiates, prescription sedatives, both prescription opiates and sedatives, cannabis use, and hazardous alcohol consumption. Method: Participants were a community sample of 238 U.S. military personnel who had deployed one or more times (71.0% males; M =33.3 years; SD =3.2). Results: In our sample, rates of past week misuse were as follows: 21.0% prescription opiates, 25.6% prescription sedatives, 16.4% both prescription opiates and sedative medications. With respect to cannabis use and alcohol consumption, 14.7% reported past-week cannabis use and 46.2% participants reported hazardous alcohol consumption above suggested clinical cut-offs. In multivariable multinomial logistic regression analyses, combat exposure and moral injury were uniquely associated with a greater likelihood of misusing prescription opiates, sedatives, and both opiates and sedatives versus no misuse. Higher PTSD symptoms scores were uniquely associated with past week cannabis use versus no use. Further, greater combat exposure was uniquely associated with a greater likelihood of engaging in hazardous alcohol use. Conclusions: These results suggest that distinct psychosocial factors may differentially impact substance use among military personnel. Findings indicate the importance of assessing combat exposure, moral injury, PTSD, and pain to better understand substance use and treatment of military personnel.
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  Data: 2026
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