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Magnetic Resonance Imaging--Insights into Brain Injury and Outcomes in Premature Infants

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Title: Magnetic Resonance Imaging--Insights into Brain Injury and Outcomes in Premature Infants
Language: English
Authors: Mathur, Amit, Inder, Terrie
Source: Journal of Communication Disorders. Jul-Aug 2009 42(4):248-255.
Availability: Elsevier. 6277 Sea Harbor Drive, Orlando, FL 32887-4800. Tel: 877-839-7126; Tel: 407-345-4020; Fax: 407-363-1354; e-mail: usjcs@elsevier.com; Web site: http://www.elsevier.com
Peer Reviewed: Y
Physical Description: PDF
Page Count: 8
Publication Date: 2009
Document Type: Journal Articles
Reports - Research
Descriptors: Early Intervention, Injuries, Cerebral Palsy, Pregnancy, Premature Infants, Brain, Diagnostic Tests, Neurological Impairments, Mental Disorders
DOI: 10.1016/j.jcomdis.2009.03.007
ISSN: 0021-9924
Abstract: Preterm birth is a major public-health issue because of its increasing incidence combined with the frequent occurrence of subsequent behavioral, neurological, and psychiatric challenges faced by surviving infants. Approximately 10-15% of very preterm children (born less than 30 weeks gestational age) develop cerebral palsy, and 30-60% of them experience cognitive impairments. These adverse outcomes are related to a confluence of abnormal brain development along with white (WM) and gray matter (GM) injury sustained during the neonatal period. It is becoming apparent that the extra-uterine environment during this critical period (24-40 weeks gestation) in brain development has a profound and long lasting impact on the premature infant. Magnetic resonance imaging in the neonatal period and infancy provides a non-invasive, "in vivo" assessment of brain development and extent of brain injury. This not only helps understand the extent and timing of injury but also identifies infants who may benefit from early intervention to minimize the impact of the injury. (Contains 1 figure.)
Abstractor: As Provided
Entry Date: 2009
Accession Number: EJ843022
Database: ERIC
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  Data: Elsevier. 6277 Sea Harbor Drive, Orlando, FL 32887-4800. Tel: 877-839-7126; Tel: 407-345-4020; Fax: 407-363-1354; e-mail: usjcs@elsevier.com; Web site: http://www.elsevier.com
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  Data: Preterm birth is a major public-health issue because of its increasing incidence combined with the frequent occurrence of subsequent behavioral, neurological, and psychiatric challenges faced by surviving infants. Approximately 10-15% of very preterm children (born less than 30 weeks gestational age) develop cerebral palsy, and 30-60% of them experience cognitive impairments. These adverse outcomes are related to a confluence of abnormal brain development along with white (WM) and gray matter (GM) injury sustained during the neonatal period. It is becoming apparent that the extra-uterine environment during this critical period (24-40 weeks gestation) in brain development has a profound and long lasting impact on the premature infant. Magnetic resonance imaging in the neonatal period and infancy provides a non-invasive, "in vivo" assessment of brain development and extent of brain injury. This not only helps understand the extent and timing of injury but also identifies infants who may benefit from early intervention to minimize the impact of the injury. (Contains 1 figure.)
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