Validation of the Autism Spectrum Screening Questionnaire, Mandarin Chinese Version (CH-ASSQ) in Beijing, China

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Bibliographic Details
Title: Validation of the Autism Spectrum Screening Questionnaire, Mandarin Chinese Version (CH-ASSQ) in Beijing, China
Language: English
Authors: Guo, Yan-Qing, Tang, Yilang, Rice, Catherine, Lee, Li-Ching, Wang, Yu-Feng, Cubells, Joseph F.
Source: Autism: The International Journal of Research and Practice. Nov 2011 15(6):713-727.
Availability: SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: http://sagepub.com
Peer Reviewed: Y
Page Count: 15
Publication Date: 2011
Document Type: Journal Articles
Reports - Research
Descriptors: Attention Deficit Hyperactivity Disorder, Schizophrenia, Autism, Foreign Countries, Mandarin Chinese, Screening Tests, Pervasive Developmental Disorders, Mental Disorders, Comparative Analysis, Parents, Scores, Urban Schools, Questionnaires, Cutting Scores, Translation
Geographic Terms: China (Beijing)
DOI: 10.1177/1362361310396383
ISSN: 1362-3613
Abstract: Background: This study screened children in Beijing, China, in order to establish the validity of a Mandarin Chinese translation of the ASSQ. Methods: We recruited children diagnosed with autism spectrum disorders (ASDs), attention deficit/hyperactivity disorder (ADHD), childhood-onset schizophrenia (COS) (DSM-IV diagnoses made independently by two senior psychiatrists) and unaffected children attending a public school in Beijing. Their parents were asked to complete the CH-ASSQ. Results: Data from the parents of 94 children with ASD (mean age: 81 plus or minus 47 months), 45 with ADHD (106 plus or minus 27 months), 26 with COS (166 plus or minus 36 months), and 120 unaffected control (72 plus or minus 16 months) were collected. The total scores of ASSQ in children with ASD, ADHD, COS, and unaffected controls were 25.3 plus or minus 9.2, 10.4 plus or minus 7.1, 12.2 plus or minus 10.6, and 5.2 plus or minus 6.6 respectively. Total ASSQ scores of children with ASD were significantly higher than in any other group (all p less than 0.0001). ROC analysis of ASD versus unaffected control subjects showed the area under curve was 0.957, with a cutoff of 12 having the maximum sensitivity (0.957) and specificity (0.825). Conclusions: Our pilot data suggest that CH-ASSQ successfully differentiates clinically diagnosed ASD patients from unaffected controls, as well as from patients with ADHD and COS. The instrument might therefore be useful for screening for ASD in urban Mandarin Chinese-speaking populations. (Contains 1 figure and 3 tables.)
Abstractor: As Provided
Number of References: 48
Entry Date: 2012
Accession Number: EJ953857
Database: ERIC
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Abstract:Background: This study screened children in Beijing, China, in order to establish the validity of a Mandarin Chinese translation of the ASSQ. Methods: We recruited children diagnosed with autism spectrum disorders (ASDs), attention deficit/hyperactivity disorder (ADHD), childhood-onset schizophrenia (COS) (DSM-IV diagnoses made independently by two senior psychiatrists) and unaffected children attending a public school in Beijing. Their parents were asked to complete the CH-ASSQ. Results: Data from the parents of 94 children with ASD (mean age: 81 plus or minus 47 months), 45 with ADHD (106 plus or minus 27 months), 26 with COS (166 plus or minus 36 months), and 120 unaffected control (72 plus or minus 16 months) were collected. The total scores of ASSQ in children with ASD, ADHD, COS, and unaffected controls were 25.3 plus or minus 9.2, 10.4 plus or minus 7.1, 12.2 plus or minus 10.6, and 5.2 plus or minus 6.6 respectively. Total ASSQ scores of children with ASD were significantly higher than in any other group (all p less than 0.0001). ROC analysis of ASD versus unaffected control subjects showed the area under curve was 0.957, with a cutoff of 12 having the maximum sensitivity (0.957) and specificity (0.825). Conclusions: Our pilot data suggest that CH-ASSQ successfully differentiates clinically diagnosed ASD patients from unaffected controls, as well as from patients with ADHD and COS. The instrument might therefore be useful for screening for ASD in urban Mandarin Chinese-speaking populations. (Contains 1 figure and 3 tables.)
ISSN:1362-3613
DOI:10.1177/1362361310396383