TUMORES CARCINOIDES PULMONARES TRATADOS QUIRÚRGICAMENTE VALOR PRONÓSTICO DE LA 7a ESTADIFICACIÓN TNM.

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Title: TUMORES CARCINOIDES PULMONARES TRATADOS QUIRÚRGICAMENTE VALOR PRONÓSTICO DE LA 7a ESTADIFICACIÓN TNM.
Alternate Title: Surgically treated bronchopulmonary carcinoid tumours. Prognostic value of TNM staging 7a edition.
Authors: PATANÉ, ANA K.1,2 cirugiapulmon@gmail.com, POLERI, CLAUDIA1, MARTÍN, CLAUDIO1,2, PUPARELI, CARMEN1,2, ROSALES, ADOLFO1,2, RIVERO, HÉCTOR1, ROJAS, OSCAR1, ROSENBERG, MOISÉS1,2
Source: Medicina (Buenos Aires). 2014, Vol. 74 Issue 6, p437-442. 6p. 3 Charts, 3 Graphs.
Abstract (English): We analyzed 43 women (61%) and 28 men (39%) surgically treated for carcinoid tumors from Jan/1975 to Dec/2011. Median age: 38 years (13-67). Typical carcinoid (TC) appeared in 63 (89%) patients, 8 (11%) suffered from atypical carcinoid (AC). Median follow-up: 4 years (1-24). TC stages were: IA = 33 (52%), IB = 10 (16%), IIA = 2 (3%), IIB = 2 (3%), IIIA = 12 (19%) and IIIB = 2 (3%); AC stages were: IA = 1 (12.5%), IIB = 1 (12.5%), IIIA = 2 (25%) and IIIB = 4 (50%). TNM classification did not show significant differences on 5-years survival period by stage (p = 0.689), even according to histological type (TC: p = 0.547; AC: p = 0.592). The disease-free survival rate was significantly lower (TC: 3 years vs. AC: 2 years, p = 0.000) and relapses were more frequent in AC (AC: 50% vs. TC: 2%, p = 0.000). The 7th TNM staging was not influential in estimating survival from carcinoid tumours in our population. The histological subtype was a better prognostic factor. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Con el objetivo de evaluar el valor pronóstico de la 7a estadificación TNM se analizaron 43 mujeres (61%) y 28 hombres (39%) con diagnóstico de tumor carcinoide tratados quirúrgicamente desde enero/1975 hasta diciembre/2011. Mediana de edad: 38 años (13-67). Presentaron carcinoide típico (CT) 63 (89%) pacientes y 8 (11%) carcinoide atípico (CA). Mediana de seguimiento: 4 años (1 - 24 años). Los estadios correspondientes a CT fueron: IA = 33 (52%), IB = 10 (16%), IIA = 2 (3%), IIB = 2 (3%), IIIA = 12 (19%) y IIIB = 2 (3%); para los CA fueron: IA = 1 (12.5%), IIB = 1 (12.5%), IIIA = 2 (25%) y IIIB = 4 (50%). No hubo diferencia estadísticamente significativa en la supervivencia global a cinco años en el análisis estratificando por estadios (p = 0.689), ni analizando separadamente cada tipo histológico (CT p = 0.547; CA p = 0.592). El intervalo libre de enfermedad fue significativamente menor (CT: 3 años vs CA: 2 años, p = 0.000) y las recaídas más frecuentes en el grupo de carcinoides atípicos (CA: 50% vs CT: 2%, p = 0.000). Los pacientes con CT presentaron buena evolución aun en estadios avanzados, mientras que los que tuvieron CA presentaron menor tiempo de supervivencia e intervalo libre de enfermedad, y mayor frecuencia de recurrencia. El subtipo histológico resultó un factor significativo de pronóstico, mientras que la 7a estadificación TNM no contribuyó en predecir la supervivencia en los tumores carcinoides. [ABSTRACT FROM AUTHOR]
Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: TUMORES CARCINOIDES PULMONARES TRATADOS QUIRÚRGICAMENTE VALOR PRONÓSTICO DE LA 7<superscript>a</superscript> ESTADIFICACIÓN TNM.
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  Data: Surgically treated bronchopulmonary carcinoid tumours. Prognostic value of TNM staging 7a edition.
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  Data: <searchLink fieldCode="AR" term="%22PATANÉ%2C+ANA+K%2E%22">PATANÉ, ANA K.</searchLink><relatesTo>1,2</relatesTo><i> cirugiapulmon@gmail.com</i><br /><searchLink fieldCode="AR" term="%22POLERI%2C+CLAUDIA%22">POLERI, CLAUDIA</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22MARTÍN%2C+CLAUDIO%22">MARTÍN, CLAUDIO</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22PUPARELI%2C+CARMEN%22">PUPARELI, CARMEN</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22ROSALES%2C+ADOLFO%22">ROSALES, ADOLFO</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22RIVERO%2C+HÉCTOR%22">RIVERO, HÉCTOR</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22ROJAS%2C+OSCAR%22">ROJAS, OSCAR</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22ROSENBERG%2C+MOISÉS%22">ROSENBERG, MOISÉS</searchLink><relatesTo>1,2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Medicina+%28Buenos+Aires%29%22">Medicina (Buenos Aires)</searchLink>. 2014, Vol. 74 Issue 6, p437-442. 6p. 3 Charts, 3 Graphs.
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: We analyzed 43 women (61%) and 28 men (39%) surgically treated for carcinoid tumors from Jan/1975 to Dec/2011. Median age: 38 years (13-67). Typical carcinoid (TC) appeared in 63 (89%) patients, 8 (11%) suffered from atypical carcinoid (AC). Median follow-up: 4 years (1-24). TC stages were: IA = 33 (52%), IB = 10 (16%), IIA = 2 (3%), IIB = 2 (3%), IIIA = 12 (19%) and IIIB = 2 (3%); AC stages were: IA = 1 (12.5%), IIB = 1 (12.5%), IIIA = 2 (25%) and IIIB = 4 (50%). TNM classification did not show significant differences on 5-years survival period by stage (p = 0.689), even according to histological type (TC: p = 0.547; AC: p = 0.592). The disease-free survival rate was significantly lower (TC: 3 years vs. AC: 2 years, p = 0.000) and relapses were more frequent in AC (AC: 50% vs. TC: 2%, p = 0.000). The 7th TNM staging was not influential in estimating survival from carcinoid tumours in our population. The histological subtype was a better prognostic factor. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Con el objetivo de evaluar el valor pronóstico de la 7a estadificación TNM se analizaron 43 mujeres (61%) y 28 hombres (39%) con diagnóstico de tumor carcinoide tratados quirúrgicamente desde enero/1975 hasta diciembre/2011. Mediana de edad: 38 años (13-67). Presentaron carcinoide típico (CT) 63 (89%) pacientes y 8 (11%) carcinoide atípico (CA). Mediana de seguimiento: 4 años (1 - 24 años). Los estadios correspondientes a CT fueron: IA = 33 (52%), IB = 10 (16%), IIA = 2 (3%), IIB = 2 (3%), IIIA = 12 (19%) y IIIB = 2 (3%); para los CA fueron: IA = 1 (12.5%), IIB = 1 (12.5%), IIIA = 2 (25%) y IIIB = 4 (50%). No hubo diferencia estadísticamente significativa en la supervivencia global a cinco años en el análisis estratificando por estadios (p = 0.689), ni analizando separadamente cada tipo histológico (CT p = 0.547; CA p = 0.592). El intervalo libre de enfermedad fue significativamente menor (CT: 3 años vs CA: 2 años, p = 0.000) y las recaídas más frecuentes en el grupo de carcinoides atípicos (CA: 50% vs CT: 2%, p = 0.000). Los pacientes con CT presentaron buena evolución aun en estadios avanzados, mientras que los que tuvieron CA presentaron menor tiempo de supervivencia e intervalo libre de enfermedad, y mayor frecuencia de recurrencia. El subtipo histológico resultó un factor significativo de pronóstico, mientras que la 7a estadificación TNM no contribuyó en predecir la supervivencia en los tumores carcinoides. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Text: Spanish
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