Cervical spine involvement as initial manifestation of rheumatoid arthritis: a case report.

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Title: Cervical spine involvement as initial manifestation of rheumatoid arthritis: a case report.
Authors: Silva, Inês1, Araújo, Filipe1,2, Sepriano, Alexandre1,3, Nero, Patrícia1,4, Marques, Luís5, Reizinho, Carla5, Branco, Jaime C.1,4
Source: Acta Reumatológica Portuguesa. Jan-Mar2015, Vol. 40 Issue 1, p68-71. 4p.
Subjects: CERVICAL vertebrae diseases, RHEUMATOID arthritis diagnosis, SYNOVITIS, JOINT pain, MAGNETIC resonance imaging, ETIOLOGY of diseases, THERAPEUTICS
Abstract: Rheumatoid arthritis' synovitis affects mostly small hand and feet joints, although it may compromise any joint with a synovial lining. Cervical involvement occurs usually in longstanding disease in over half of these patients. We report the case of a 35-year old male patient who was referred to our outpatient clinic for a 2-year severe and disabling inflammatory neck pain, with incomplete response to intramuscular non-steroidal anti-inflammatory drugs and unremarkable cervical imaging studies. He also mentioned self-limited episodes of symmetric polyarthralgia involving hands, wrists, elbows, knees and feet, which started after his cervical complaints. On laboratorial workup, positive rheumatoid factor and anti-citrullinated peptide antibody and negative HLA-B27 were found. Cervical spine magnetic resonance imaging revealed atlantoaxial subluxation and odontoid process inflammatory pannus and erosions. Rheumatoid arthritis with cervical spine involvement as initial manifestation of disease was the definite diagnosis. The patient was started on methotrexate and prednisone and he was referred to neurosurgery outpatient clinic for cervical spine fixation. [ABSTRACT FROM AUTHOR]
Copyright of Acta Reumatológica Portuguesa is the property of Sociedade Portuguesa de Reumatologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Cervical spine involvement as initial manifestation of rheumatoid arthritis: a case report.
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  Data: <searchLink fieldCode="AR" term="%22Silva%2C+Inês%22">Silva, Inês</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Araújo%2C+Filipe%22">Araújo, Filipe</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Sepriano%2C+Alexandre%22">Sepriano, Alexandre</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Nero%2C+Patrícia%22">Nero, Patrícia</searchLink><relatesTo>1,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Marques%2C+Luís%22">Marques, Luís</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Reizinho%2C+Carla%22">Reizinho, Carla</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Branco%2C+Jaime+C%2E%22">Branco, Jaime C.</searchLink><relatesTo>1,4</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Acta+Reumatológica+Portuguesa%22">Acta Reumatológica Portuguesa</searchLink>. Jan-Mar2015, Vol. 40 Issue 1, p68-71. 4p.
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  Data: <searchLink fieldCode="DE" term="%22CERVICAL+vertebrae+diseases%22">CERVICAL vertebrae diseases</searchLink><br /><searchLink fieldCode="DE" term="%22RHEUMATOID+arthritis+diagnosis%22">RHEUMATOID arthritis diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22SYNOVITIS%22">SYNOVITIS</searchLink><br /><searchLink fieldCode="DE" term="%22JOINT+pain%22">JOINT pain</searchLink><br /><searchLink fieldCode="DE" term="%22MAGNETIC+resonance+imaging%22">MAGNETIC resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22ETIOLOGY+of+diseases%22">ETIOLOGY of diseases</searchLink><br /><searchLink fieldCode="DE" term="%22THERAPEUTICS%22">THERAPEUTICS</searchLink>
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  Label: Abstract
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  Data: Rheumatoid arthritis' synovitis affects mostly small hand and feet joints, although it may compromise any joint with a synovial lining. Cervical involvement occurs usually in longstanding disease in over half of these patients. We report the case of a 35-year old male patient who was referred to our outpatient clinic for a 2-year severe and disabling inflammatory neck pain, with incomplete response to intramuscular non-steroidal anti-inflammatory drugs and unremarkable cervical imaging studies. He also mentioned self-limited episodes of symmetric polyarthralgia involving hands, wrists, elbows, knees and feet, which started after his cervical complaints. On laboratorial workup, positive rheumatoid factor and anti-citrullinated peptide antibody and negative HLA-B27 were found. Cervical spine magnetic resonance imaging revealed atlantoaxial subluxation and odontoid process inflammatory pannus and erosions. Rheumatoid arthritis with cervical spine involvement as initial manifestation of disease was the definite diagnosis. The patient was started on methotrexate and prednisone and he was referred to neurosurgery outpatient clinic for cervical spine fixation. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Reumatológica Portuguesa is the property of Sociedade Portuguesa de Reumatologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Code: eng
        Text: English
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        StartPage: 68
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      – SubjectFull: CERVICAL vertebrae diseases
        Type: general
      – SubjectFull: RHEUMATOID arthritis diagnosis
        Type: general
      – SubjectFull: SYNOVITIS
        Type: general
      – SubjectFull: JOINT pain
        Type: general
      – SubjectFull: MAGNETIC resonance imaging
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      – SubjectFull: ETIOLOGY of diseases
        Type: general
      – SubjectFull: THERAPEUTICS
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      – TitleFull: Cervical spine involvement as initial manifestation of rheumatoid arthritis: a case report.
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            NameFull: Silva, Inês
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              M: 01
              Text: Jan-Mar2015
              Type: published
              Y: 2015
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