Programa de optimización del uso de antimicrobianos (PROA). Experiencia en un hospital secundario.

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Title: Programa de optimización del uso de antimicrobianos (PROA). Experiencia en un hospital secundario.
Alternate Title: A program for optimizing the use of antimicrobials (PROA): experience in a regional hospital.
Authors: Ugalde-Espiñeira, Jon1 j.ugalde.espineira@osakidetza.eus, Bilbao-Aguirregomezcorta, Jaione2, Sanjuan-López, Ainhoa Zuriñe1, Floristán-Imízcoz, Carmen2, Elorduy-Otazua, Luis3, Viciola-García, Margarita4
Source: Revista Española de Quimioterapia. ago2016, Vol. 29 Issue 4, p183-189. 7p.
Abstract (English): Introduction. Programs for optimizing the use of antibiotics (PROA) or antimicrobial stewardship programs are multidisciplinary programs developed in response to the increase of antibiotic resistant bacteria, the objective of which are to improve clinical results, to minimize adverse events and to reduce costs associated with the use of antimicrobials. The implementation of a PROA program in a 128-bed general hospital and the results obtained at 6 months are here reported. Methods. An intervention quasi-experimental study with historical control group was designed with the objective of assessing the impact of a PROA program with a non-restrictive intervention model to help prescription, with a direct and bidirectional intervention. The basis of the program is an optimization audit of the use of antimicrobials with not imposed personalized recommendations and the use of information technologies applied to this setting. The impact on the pharmaceutical consumption and costs, cost per process, mean hospital stay, percentage of readmissions to the hospital are described. Results. A total of 307 audits were performed. In 65.8% of cases, treatment was discontinued between the 7th and the 10th day. The main reasons of treatment discontinuation were completeness of treatment (43.6%) and lack of indication (14.7%). The reduction of pharmaceutical expenditure was 8.59% (P = 0.049) and 5.61% of the consumption in DDD/100 stays (P=0.180). The costs by processes in general surgery showed a 3.14% decrease (p=0.000). Conclusion. The results obtained support the efficiency of these programs in small size hospitals with limited resources. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción. Los programas de optimización del uso de antimicrobianos (PROA) son programas multidisciplinares que surgen ante el aumento de los microorganismos resistentes a los antimicrobianos, con el objetivo de mejorar los resultados clínicos, minimizar efectos adversos y reducir el gasto derivado de su uso. Se describe la implantación de este programa en un hospital general de 128 camas y sus resultados tras 6 meses. Material y métodos. Estudio prospectivo de intervención cuasi-experimental con grupo de control histórico con el objetivo de evaluar el impacto de un programa PROA consistente en un modelo de intervención no restrictivo, de ayuda a la prescripción con intervención directa y bidireccional. La base es una auditoría de optimización del uso de antimicrobianos con recomendaciones personalizadas no impositivas y el uso de tecnologías de información aplicadas a este entorno. Describimos el impacto en el consumo y gasto farmacéutico, coste por proceso, estancia media y porcentaje de reingresos. Resultados. Se han realizado 307 auditorías. En el 65,8% de los tratamientos se suspendieron entre el séptimo y décimo día. Los principales motivos de interrupción son tratamiento completado (43,6%) y ausencia de indicación (14,7%). La reducción del gasto farmacéutico fue del 8,59% (P=0,049) y del 5,61% del consumo en DDD/100 estancias (P=0,180). Los costes por proceso en cirugía general se han reducido un 3,14% (p=0,000). Conclusión. Los resultados obtenidos avalan la eficiencia de estos programas en hospitales de pequeño tamaño con recursos limitados. [ABSTRACT FROM AUTHOR]
Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Programa de optimización del uso de antimicrobianos (PROA). Experiencia en un hospital secundario.
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  Data: A program for optimizing the use of antimicrobials (PROA): experience in a regional hospital.
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  Data: <searchLink fieldCode="AR" term="%22Ugalde-Espiñeira%2C+Jon%22">Ugalde-Espiñeira, Jon</searchLink><relatesTo>1</relatesTo><i> j.ugalde.espineira@osakidetza.eus</i><br /><searchLink fieldCode="AR" term="%22Bilbao-Aguirregomezcorta%2C+Jaione%22">Bilbao-Aguirregomezcorta, Jaione</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Sanjuan-López%2C+Ainhoa+Zuriñe%22">Sanjuan-López, Ainhoa Zuriñe</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Floristán-Imízcoz%2C+Carmen%22">Floristán-Imízcoz, Carmen</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Elorduy-Otazua%2C+Luis%22">Elorduy-Otazua, Luis</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Viciola-García%2C+Margarita%22">Viciola-García, Margarita</searchLink><relatesTo>4</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Revista+Española+de+Quimioterapia%22">Revista Española de Quimioterapia</searchLink>. ago2016, Vol. 29 Issue 4, p183-189. 7p.
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Introduction. Programs for optimizing the use of antibiotics (PROA) or antimicrobial stewardship programs are multidisciplinary programs developed in response to the increase of antibiotic resistant bacteria, the objective of which are to improve clinical results, to minimize adverse events and to reduce costs associated with the use of antimicrobials. The implementation of a PROA program in a 128-bed general hospital and the results obtained at 6 months are here reported. Methods. An intervention quasi-experimental study with historical control group was designed with the objective of assessing the impact of a PROA program with a non-restrictive intervention model to help prescription, with a direct and bidirectional intervention. The basis of the program is an optimization audit of the use of antimicrobials with not imposed personalized recommendations and the use of information technologies applied to this setting. The impact on the pharmaceutical consumption and costs, cost per process, mean hospital stay, percentage of readmissions to the hospital are described. Results. A total of 307 audits were performed. In 65.8% of cases, treatment was discontinued between the 7th and the 10th day. The main reasons of treatment discontinuation were completeness of treatment (43.6%) and lack of indication (14.7%). The reduction of pharmaceutical expenditure was 8.59% (P = 0.049) and 5.61% of the consumption in DDD/100 stays (P=0.180). The costs by processes in general surgery showed a 3.14% decrease (p=0.000). Conclusion. The results obtained support the efficiency of these programs in small size hospitals with limited resources. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Introducción. Los programas de optimización del uso de antimicrobianos (PROA) son programas multidisciplinares que surgen ante el aumento de los microorganismos resistentes a los antimicrobianos, con el objetivo de mejorar los resultados clínicos, minimizar efectos adversos y reducir el gasto derivado de su uso. Se describe la implantación de este programa en un hospital general de 128 camas y sus resultados tras 6 meses. Material y métodos. Estudio prospectivo de intervención cuasi-experimental con grupo de control histórico con el objetivo de evaluar el impacto de un programa PROA consistente en un modelo de intervención no restrictivo, de ayuda a la prescripción con intervención directa y bidireccional. La base es una auditoría de optimización del uso de antimicrobianos con recomendaciones personalizadas no impositivas y el uso de tecnologías de información aplicadas a este entorno. Describimos el impacto en el consumo y gasto farmacéutico, coste por proceso, estancia media y porcentaje de reingresos. Resultados. Se han realizado 307 auditorías. En el 65,8% de los tratamientos se suspendieron entre el séptimo y décimo día. Los principales motivos de interrupción son tratamiento completado (43,6%) y ausencia de indicación (14,7%). La reducción del gasto farmacéutico fue del 8,59% (P=0,049) y del 5,61% del consumo en DDD/100 estancias (P=0,180). Los costes por proceso en cirugía general se han reducido un 3,14% (p=0,000). Conclusión. Los resultados obtenidos avalan la eficiencia de estos programas en hospitales de pequeño tamaño con recursos limitados. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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