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Síndrome DRESS: presentación de un caso clínico.

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Title: Síndrome DRESS: presentación de un caso clínico.
Alternate Title: DRESS Syndrome: A Clinical Case Report.
Síndrome DRESS: apresentação de um caso clínico.
Authors: García Sánchez, Marly1 marly_garcia86@hotmail.com, Valencia Maturana, Julio1
Source: Medicina UPB. ene-jun2016, Vol. 35 Issue 1, p47-51. 5p.
Abstract (English): Drug reaction with eosinophilia and systemic symptoms (DRESS) is a potentially fatal cutaneous reaction to drugs, which has an unclear pathogenesis. It is commonly associated with fever, lymphadenopathy, visceral involvement, and hematologic disorders including eosinophilia. Herein, we present the case of a 22-year-old man who had been receiving antibiotics and analgesics for a respiratory infection, and developed an exanthem that spread throughout most of the body, fever, altered liver, and kidney tests. The skin biopsy was consistent with a drug reaction. The patient notably improved after discontinuation of the offending drugs and corticosteroid treatment. Prompt diagnosis through clinical and laboratory criteria is crucial given the multisystemic and potentially fatal nature of this disease. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): La reacción a medicamentos con eosinofilia y síntomas sistémicos (Dress) es una toxicodermia con alto riesgo de letalidad y cuya patogénesis es poco clara, que se asocia con fiebre, linfadenopatías, afección visceral y alteraciones hematológicas que generalmente incluyen eosinofilia. Se presenta el caso clínico de un hombre de 22 años, quien, tras la ingesta de antibióticos y analgésicos por infección respiratoria, presenta exantema generalizado, fiebre, alteración de pruebas hepáticas y renales. La biopsia de piel confirma reacción medicamentosa y se evidencia mejoría notoria tras la suspensión de los medicamentos sospechosos y la administración de corticoides. Es de vital importancia realizar un diagnóstico temprano mediante criterios clínicos y de laboratorio por parte del personal médico, por el carácter multisistémico y letalidad potencial de esta patología. [ABSTRACT FROM AUTHOR]
Abstract (Portuguese): A reação a medicamentos com eosinofilia e sintomas sistémicos (Dress) é uma toxicodermia com alto risco de letalidade e cuja patogénese é pouco clara, que se associa com febre, linfadenopatia, afecção visceral e alterações hematológicas que geralmente incluem eosinofilia. Se apresenta o caso clínico de um homem de 22 anos, quem, após a ingestão de antibióticos e analgésicos por infecção respiratória, apresenta exantema generalizado, febre, alteração de provas hepáticas e renais. A biopsia de pele confirma reação medicamentosa e se evidencia melhoria notória após a suspensão dos medicamentos suspeitosos e a administração de corticoides. É de vital importância realizar um diagnóstico precoce mediante critérios clínicos e de laboratório por parte do pessoal médico, pelo carácter multissistêmico e letalidade potencial desta patologia. [ABSTRACT FROM AUTHOR]
Copyright of Medicina UPB is the property of Universidad Pontificia Bolivariana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
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  Data: Síndrome DRESS: presentación de un caso clínico.
– Name: TitleAlt
  Label: Alternate Title
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  Data: DRESS Syndrome: A Clinical Case Report.<br />Síndrome DRESS: apresentação de um caso clínico.
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  Group: Au
  Data: <searchLink fieldCode="AR" term="%22García+Sánchez%2C+Marly%22">García Sánchez, Marly</searchLink><relatesTo>1</relatesTo><i> marly_garcia86@hotmail.com</i><br /><searchLink fieldCode="AR" term="%22Valencia+Maturana%2C+Julio%22">Valencia Maturana, Julio</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Medicina+UPB%22">Medicina UPB</searchLink>. ene-jun2016, Vol. 35 Issue 1, p47-51. 5p.
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a potentially fatal cutaneous reaction to drugs, which has an unclear pathogenesis. It is commonly associated with fever, lymphadenopathy, visceral involvement, and hematologic disorders including eosinophilia. Herein, we present the case of a 22-year-old man who had been receiving antibiotics and analgesics for a respiratory infection, and developed an exanthem that spread throughout most of the body, fever, altered liver, and kidney tests. The skin biopsy was consistent with a drug reaction. The patient notably improved after discontinuation of the offending drugs and corticosteroid treatment. Prompt diagnosis through clinical and laboratory criteria is crucial given the multisystemic and potentially fatal nature of this disease. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: La reacción a medicamentos con eosinofilia y síntomas sistémicos (Dress) es una toxicodermia con alto riesgo de letalidad y cuya patogénesis es poco clara, que se asocia con fiebre, linfadenopatías, afección visceral y alteraciones hematológicas que generalmente incluyen eosinofilia. Se presenta el caso clínico de un hombre de 22 años, quien, tras la ingesta de antibióticos y analgésicos por infección respiratoria, presenta exantema generalizado, fiebre, alteración de pruebas hepáticas y renales. La biopsia de piel confirma reacción medicamentosa y se evidencia mejoría notoria tras la suspensión de los medicamentos sospechosos y la administración de corticoides. Es de vital importancia realizar un diagnóstico temprano mediante criterios clínicos y de laboratorio por parte del personal médico, por el carácter multisistémico y letalidad potencial de esta patología. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Portuguese)
  Group: Ab
  Data: A reação a medicamentos com eosinofilia e sintomas sistémicos (Dress) é uma toxicodermia com alto risco de letalidade e cuja patogénese é pouco clara, que se associa com febre, linfadenopatia, afecção visceral e alterações hematológicas que geralmente incluem eosinofilia. Se apresenta o caso clínico de um homem de 22 anos, quem, após a ingestão de antibióticos e analgésicos por infecção respiratória, apresenta exantema generalizado, febre, alteração de provas hepáticas e renais. A biopsia de pele confirma reação medicamentosa e se evidencia melhoria notória após a suspensão dos medicamentos suspeitosos e a administração de corticoides. É de vital importância realizar um diagnóstico precoce mediante critérios clínicos e de laboratório por parte do pessoal médico, pelo carácter multissistêmico e letalidade potencial desta patologia. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Medicina UPB is the property of Universidad Pontificia Bolivariana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.18566/medupb.v35n1.a07
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        Text: Spanish
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            NameFull: García Sánchez, Marly
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            NameFull: Valencia Maturana, Julio
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              Text: ene-jun2016
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              Y: 2016
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