Renal function is similar in solitary kidneys from patients with and without diabetes.
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| Title: | Renal function is similar in solitary kidneys from patients with and without diabetes. |
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| Alternate Title: | La función renal es similar en los riñones únicos de los pacientes con y sin diabetes. |
| Authors: | Gluhovschi, Cristina1 gluh@umft.ro, Gluhovschi, Gheorghe2, Gadalean, Florica1,3, Velciov, Silvia1,3, Petrica, Ligia1,3, Timar, Bogdan3,4, Kaycsa, Adriana3,5, Timar, Romulus3,6 |
| Source: | Nefrologia. mar/abr2017, Vol. 37 Issue 2, p195-198. 4p. |
| Subjects: | ORGAN donors, PANDEMICS, SYSTOLIC blood pressure, PROTEINURIA, TRANSPLANTATION of organs, tissues, etc., BLOOD pressure |
| Abstract (English): | Objectives: Due to the shortage of living kidney donors and the current diabetes mellitus (DM) pandemic, studying the association of solitary kidney (SK) with DM is of paramount importance. Our aim was to assess the significance of the association between SK and DM. Materials and methods: Eighty-four patients with SK and DM (group A), with a mean age of 62.46 ± 12.72 years, of whom 36 were males and 48 were females, were enrolled in the study. The control group (group B) comprised 84 SK patients without DM of similar age and duration of existence of a SK. Mean age: 61.58 ± 8.22 years, 23 males and 61 females. Serum creatinine, GFR (CKD-EPI), glycaemia, cholesterol, triglycerides, uric acid, proteinuria/24 h, systolic blood pressure (SBP), diastolic blood pressure (DBP) and BMI were assessed. Results: The group of patients with SK and DM (group A) had a higher BMI (p = 0.0007), higher metabolic abnormalities (higher glycaemia [p < 0.001], triglycerides [p = 0.0004], uric acid [p = 0.019] and proteinuria/24 h [p = 0.006]). The study group also had a higher prevalence of hypertension (p = 0.003) and coronary artery disease (p = 0.031). Conclusions: We found a higher value of proteinuria in the study group, significant metabolic abnormalities, as well as a higher prevalence of hypertension and coronary artery disease. However, no differences with respect to GFR were found, which could have significant implications for transplantation. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Objectivos: Dada la reducción del número de los donantes vivos de riñones y la pandemia de diabetes mellitus (DM), estudiar la asociación del riñón único (RU) con la DM es de la mayor importancia. Nuestro objetivo fue evaluar la significación de la asociación entre el RU y la DM. Material y métodos: Han sido estudiados 84 pacientes con RU y DM (grupo A), con edad media de 62,46 ± 12,72 años; eran 36 hombres y 48 mujeres. El grupo control (grupo B) ha estado compuesto por 84 pacientes con RU sin DM, de la misma edad y del mismo periodo de tiempo que el grupo A; la edad media de estos pacientes fue de 61,58 ± 8,22 años; eran 23 hombres y 61 mujeres. Hemos evaluado la creatinina sérica, el FG (CKD-EPI), la glucemia, el colesterol, los triglicéridos, el acido úrico, la proteinuria de 24 h, la tensión arterial sistólica (TAS), la tensión arterial diastólica (TAD) y el IMC. Resultados: El grupo de los pacientes con RU y DM (el grupo A) tuvo valores mayores del IMC (p = 0,0007), anomalías metabólicas más elevadas (la glucemia [p < 0,001], los triglicéridos [p = 0,0004], el acido úrico [p = 0,019] y una proteinuria/24 h también más elevada [p = 0,006]). El grupo de estudio tuvo también una prevalencia elevada de la TA (p = 0,003) y de la enfermedad arterial coronaria (p = 0,031). Conclusiones: Hemos encontrado un valor más elevado de la proteinuria en el grupo estudiado, anomalías metabólicas importantes y también prevalencia más alta de la TA y de la enfermedad arterial coronaria, pero ninguna diferencia entre los FG, lo que puede tener una implicación importante en el trasplante. [ABSTRACT FROM AUTHOR] |
| Copyright of Nefrologia is the property of Revista Nefrologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 122745100 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Renal function is similar in solitary kidneys from patients with and without diabetes. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: La función renal es similar en los riñones únicos de los pacientes con y sin diabetes. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Gluhovschi%2C+Cristina%22">Gluhovschi, Cristina</searchLink><relatesTo>1</relatesTo><i> gluh@umft.ro</i><br /><searchLink fieldCode="AR" term="%22Gluhovschi%2C+Gheorghe%22">Gluhovschi, Gheorghe</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Gadalean%2C+Florica%22">Gadalean, Florica</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Velciov%2C+Silvia%22">Velciov, Silvia</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Petrica%2C+Ligia%22">Petrica, Ligia</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Timar%2C+Bogdan%22">Timar, Bogdan</searchLink><relatesTo>3,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Kaycsa%2C+Adriana%22">Kaycsa, Adriana</searchLink><relatesTo>3,5</relatesTo><br /><searchLink fieldCode="AR" term="%22Timar%2C+Romulus%22">Timar, Romulus</searchLink><relatesTo>3,6</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Nefrologia%22">Nefrologia</searchLink>. mar/abr2017, Vol. 37 Issue 2, p195-198. 4p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22ORGAN+donors%22">ORGAN donors</searchLink><br /><searchLink fieldCode="DE" term="%22PANDEMICS%22">PANDEMICS</searchLink><br /><searchLink fieldCode="DE" term="%22SYSTOLIC+blood+pressure%22">SYSTOLIC blood pressure</searchLink><br /><searchLink fieldCode="DE" term="%22PROTEINURIA%22">PROTEINURIA</searchLink><br /><searchLink fieldCode="DE" term="%22TRANSPLANTATION+of+organs%2C+tissues%2C+etc%2E%22">TRANSPLANTATION of organs, tissues, etc.</searchLink><br /><searchLink fieldCode="DE" term="%22BLOOD+pressure%22">BLOOD pressure</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Objectives: Due to the shortage of living kidney donors and the current diabetes mellitus (DM) pandemic, studying the association of solitary kidney (SK) with DM is of paramount importance. Our aim was to assess the significance of the association between SK and DM. Materials and methods: Eighty-four patients with SK and DM (group A), with a mean age of 62.46 ± 12.72 years, of whom 36 were males and 48 were females, were enrolled in the study. The control group (group B) comprised 84 SK patients without DM of similar age and duration of existence of a SK. Mean age: 61.58 ± 8.22 years, 23 males and 61 females. Serum creatinine, GFR (CKD-EPI), glycaemia, cholesterol, triglycerides, uric acid, proteinuria/24 h, systolic blood pressure (SBP), diastolic blood pressure (DBP) and BMI were assessed. Results: The group of patients with SK and DM (group A) had a higher BMI (p = 0.0007), higher metabolic abnormalities (higher glycaemia [p < 0.001], triglycerides [p = 0.0004], uric acid [p = 0.019] and proteinuria/24 h [p = 0.006]). The study group also had a higher prevalence of hypertension (p = 0.003) and coronary artery disease (p = 0.031). Conclusions: We found a higher value of proteinuria in the study group, significant metabolic abnormalities, as well as a higher prevalence of hypertension and coronary artery disease. However, no differences with respect to GFR were found, which could have significant implications for transplantation. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Objectivos: Dada la reducción del número de los donantes vivos de riñones y la pandemia de diabetes mellitus (DM), estudiar la asociación del riñón único (RU) con la DM es de la mayor importancia. Nuestro objetivo fue evaluar la significación de la asociación entre el RU y la DM. Material y métodos: Han sido estudiados 84 pacientes con RU y DM (grupo A), con edad media de 62,46 ± 12,72 años; eran 36 hombres y 48 mujeres. El grupo control (grupo B) ha estado compuesto por 84 pacientes con RU sin DM, de la misma edad y del mismo periodo de tiempo que el grupo A; la edad media de estos pacientes fue de 61,58 ± 8,22 años; eran 23 hombres y 61 mujeres. Hemos evaluado la creatinina sérica, el FG (CKD-EPI), la glucemia, el colesterol, los triglicéridos, el acido úrico, la proteinuria de 24 h, la tensión arterial sistólica (TAS), la tensión arterial diastólica (TAD) y el IMC. Resultados: El grupo de los pacientes con RU y DM (el grupo A) tuvo valores mayores del IMC (p = 0,0007), anomalías metabólicas más elevadas (la glucemia [p < 0,001], los triglicéridos [p = 0,0004], el acido úrico [p = 0,019] y una proteinuria/24 h también más elevada [p = 0,006]). El grupo de estudio tuvo también una prevalencia elevada de la TA (p = 0,003) y de la enfermedad arterial coronaria (p = 0,031). Conclusiones: Hemos encontrado un valor más elevado de la proteinuria en el grupo estudiado, anomalías metabólicas importantes y también prevalencia más alta de la TA y de la enfermedad arterial coronaria, pero ninguna diferencia entre los FG, lo que puede tener una implicación importante en el trasplante. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Nefrologia is the property of Revista Nefrologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.nefro.2016.09.019 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 4 StartPage: 195 Subjects: – SubjectFull: ORGAN donors Type: general – SubjectFull: PANDEMICS Type: general – SubjectFull: SYSTOLIC blood pressure Type: general – SubjectFull: PROTEINURIA Type: general – SubjectFull: TRANSPLANTATION of organs, tissues, etc. Type: general – SubjectFull: BLOOD pressure Type: general Titles: – TitleFull: Renal function is similar in solitary kidneys from patients with and without diabetes. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gluhovschi, Cristina – PersonEntity: Name: NameFull: Gluhovschi, Gheorghe – PersonEntity: Name: NameFull: Gadalean, Florica – PersonEntity: Name: NameFull: Velciov, Silvia – PersonEntity: Name: NameFull: Petrica, Ligia – PersonEntity: Name: NameFull: Timar, Bogdan – PersonEntity: Name: NameFull: Kaycsa, Adriana – PersonEntity: Name: NameFull: Timar, Romulus IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: mar/abr2017 Type: published Y: 2017 Identifiers: – Type: issn-print Value: 02116995 Numbering: – Type: volume Value: 37 – Type: issue Value: 2 Titles: – TitleFull: Nefrologia Type: main |
| ResultId | 1 |
