Pénfigo vulgar: dificultad en el diagnóstico de un tipo de dermatosis vulvar poco frecuente. Reporte de un caso.
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| Title: | Pénfigo vulgar: dificultad en el diagnóstico de un tipo de dermatosis vulvar poco frecuente. Reporte de un caso. |
|---|---|
| Alternate Title: | Vulgar pemphigus: Difficulty in diagnosis of a infrequent vulvar dermatoses. A case report. |
| Authors: | José-Gutiérrez, Y.1 yjosegu@hotmail.com, Borque-Ibañez, A.1, Baquedano-Mainar, L.1, Del Agua-Arias, C.2, Ruiz-Conde, M. A.3 |
| Source: | Ginecología y Obstetricia de México. ago2017, Vol. 85 Issue 8, p541-546. 6p. |
| Subjects: | SKIN diseases, SKIN disease treatment, DISEASE progression, HISTOLOGY, WALDENSTROM'S macroglobulinemia, PATIENTS |
| Abstract (English): | BACKGROUND: The skin diseases of the vulva are a frequent reason for consultation with both gynecologists and dermatologists. The clinical symptoms are usually vague as pruritus or stinging and patients usually consult later. OBJECTIVE: To document a case of vulgaris vulvar pemphigus, and review the incidence, clinical presentation, diagnostic strategies and treatment. CLINCAL CASE: An 86-year-old patient who came to medical service for ulcerated and burning vulvar lesions of two months of progression. A biopsy was obtained for the histological study, which resulted in acantholysis and suprabasal intraepidermal vesicle, without evidence of dyskeratosis or necrosis. We prescribe topical and oral corticosteroids during a month. Posteriorly, a control study was performed of the most recent lesion that evidenced lymphoplasmacytic inflammatory infiltrate with eosinophilic isolates, without epithelial permeation. Direct immunofluorescence test reported intercellular deposits, IgG throughout the thickness of the epidermis, and C3 in the suprabasal stratum, thus confirming the diagnosis of pemphigus vulgaris. CONCLUSIONS: For correct diagnosis it is essential the clinicpathological correlation, because many of these diseases manifest themselves almost identically. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | ANTECEDENTES: las alteraciones cutáneas de la vulva suponen un motivo frecuente de consulta a ginecólogos y dermatólogos. Los síntomas suelen ser imprecisos, con prurito y ardor, por lo que las pacientes tardan en acudir a consultar al médico. OBJETIVO: exponer un caso poco frecuente de pénfigo vulgar vulvar; además, revisar la incidencia, manifestaciones clínicas, diagnóstico y estrategias de tratamiento. CASO CLÍNICO: paciente de 86 años de edad que acudió a consulta por la aparición de lesiones vulvares ulceradas y ardorosas de dos meses de evolución. Se obtuvo una biopsia para el estudio histológico, cuyo resultado fue acantólisis y formación de una vesícula intraepidérmica suprabasal, sin evidencia de disqueratosis o necrosis. Se prescribieron corticoesteroides por vía tópica y oral durante un mes. Después de ese lapso se realizó un estudio de control, esta vez de una lesión más reciente, que evidenció infiltrado inflamatorio linfoplasmocitario con aislados eosinófilos, sin permeación del epitelio. La inmunofluorescencia directa reportó depósitos intercelulares de IgG en todo el espesor de la epidermis y de C3 en los estratos suprabasales, con lo que se confirmó el diagnóstico de pénfigo vulgar. CONCLUSIONES: para establecer el diagnóstico de las dermatosis vulvares poco frecuentes es importante efectuar una correcta correlación clínico-patológica, pues la mayor parte de estas enfermedades se manifiestan casi de forma idéntica. [ABSTRACT FROM AUTHOR] |
| Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
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| Header | DbId: lth DbLabel: MedicLatina An: 124761160 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Pénfigo vulgar: dificultad en el diagnóstico de un tipo de dermatosis vulvar poco frecuente. Reporte de un caso. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Vulgar pemphigus: Difficulty in diagnosis of a infrequent vulvar dermatoses. A case report. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22José-Gutiérrez%2C+Y%2E%22">José-Gutiérrez, Y.</searchLink><relatesTo>1</relatesTo><i> yjosegu@hotmail.com</i><br /><searchLink fieldCode="AR" term="%22Borque-Ibañez%2C+A%2E%22">Borque-Ibañez, A.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Baquedano-Mainar%2C+L%2E%22">Baquedano-Mainar, L.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Del+Agua-Arias%2C+C%2E%22">Del Agua-Arias, C.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Ruiz-Conde%2C+M%2E+A%2E%22">Ruiz-Conde, M. A.</searchLink><relatesTo>3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Ginecología+y+Obstetricia+de+México%22">Ginecología y Obstetricia de México</searchLink>. ago2017, Vol. 85 Issue 8, p541-546. 6p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22SKIN+diseases%22">SKIN diseases</searchLink><br /><searchLink fieldCode="DE" term="%22SKIN+disease+treatment%22">SKIN disease treatment</searchLink><br /><searchLink fieldCode="DE" term="%22DISEASE+progression%22">DISEASE progression</searchLink><br /><searchLink fieldCode="DE" term="%22HISTOLOGY%22">HISTOLOGY</searchLink><br /><searchLink fieldCode="DE" term="%22WALDENSTROM'S+macroglobulinemia%22">WALDENSTROM'S macroglobulinemia</searchLink><br /><searchLink fieldCode="DE" term="%22PATIENTS%22">PATIENTS</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: BACKGROUND: The skin diseases of the vulva are a frequent reason for consultation with both gynecologists and dermatologists. The clinical symptoms are usually vague as pruritus or stinging and patients usually consult later. OBJECTIVE: To document a case of vulgaris vulvar pemphigus, and review the incidence, clinical presentation, diagnostic strategies and treatment. CLINCAL CASE: An 86-year-old patient who came to medical service for ulcerated and burning vulvar lesions of two months of progression. A biopsy was obtained for the histological study, which resulted in acantholysis and suprabasal intraepidermal vesicle, without evidence of dyskeratosis or necrosis. We prescribe topical and oral corticosteroids during a month. Posteriorly, a control study was performed of the most recent lesion that evidenced lymphoplasmacytic inflammatory infiltrate with eosinophilic isolates, without epithelial permeation. Direct immunofluorescence test reported intercellular deposits, IgG throughout the thickness of the epidermis, and C3 in the suprabasal stratum, thus confirming the diagnosis of pemphigus vulgaris. CONCLUSIONS: For correct diagnosis it is essential the clinicpathological correlation, because many of these diseases manifest themselves almost identically. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: ANTECEDENTES: las alteraciones cutáneas de la vulva suponen un motivo frecuente de consulta a ginecólogos y dermatólogos. Los síntomas suelen ser imprecisos, con prurito y ardor, por lo que las pacientes tardan en acudir a consultar al médico. OBJETIVO: exponer un caso poco frecuente de pénfigo vulgar vulvar; además, revisar la incidencia, manifestaciones clínicas, diagnóstico y estrategias de tratamiento. CASO CLÍNICO: paciente de 86 años de edad que acudió a consulta por la aparición de lesiones vulvares ulceradas y ardorosas de dos meses de evolución. Se obtuvo una biopsia para el estudio histológico, cuyo resultado fue acantólisis y formación de una vesícula intraepidérmica suprabasal, sin evidencia de disqueratosis o necrosis. Se prescribieron corticoesteroides por vía tópica y oral durante un mes. Después de ese lapso se realizó un estudio de control, esta vez de una lesión más reciente, que evidenció infiltrado inflamatorio linfoplasmocitario con aislados eosinófilos, sin permeación del epitelio. La inmunofluorescencia directa reportó depósitos intercelulares de IgG en todo el espesor de la epidermis y de C3 en los estratos suprabasales, con lo que se confirmó el diagnóstico de pénfigo vulgar. CONCLUSIONES: para establecer el diagnóstico de las dermatosis vulvares poco frecuentes es importante efectuar una correcta correlación clínico-patológica, pues la mayor parte de estas enfermedades se manifiestan casi de forma idéntica. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 6 StartPage: 541 Subjects: – SubjectFull: SKIN diseases Type: general – SubjectFull: SKIN disease treatment Type: general – SubjectFull: DISEASE progression Type: general – SubjectFull: HISTOLOGY Type: general – SubjectFull: WALDENSTROM'S macroglobulinemia Type: general – SubjectFull: PATIENTS Type: general Titles: – TitleFull: Pénfigo vulgar: dificultad en el diagnóstico de un tipo de dermatosis vulvar poco frecuente. Reporte de un caso. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: José-Gutiérrez, Y. – PersonEntity: Name: NameFull: Borque-Ibañez, A. – PersonEntity: Name: NameFull: Baquedano-Mainar, L. – PersonEntity: Name: NameFull: Del Agua-Arias, C. – PersonEntity: Name: NameFull: Ruiz-Conde, M. A. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: ago2017 Type: published Y: 2017 Identifiers: – Type: issn-print Value: 03009041 Numbering: – Type: volume Value: 85 – Type: issue Value: 8 Titles: – TitleFull: Ginecología y Obstetricia de México Type: main |
| ResultId | 1 |
